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Completed Phase 3 Interventional

Ramipril and Hydrochlorothiazide Alone and in Combination for the Treatment of Essential Hypertension

ClinicalTrials.gov ID: NCT00355589

Public ClinicalTrials.gov record NCT00355589. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:25 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Multicenter, Parallel Study Evaluating the Efficacy and Safety of a Combination of Ramipril Plus Hydrochlorothiazide Versus the Component Monotherapies in Subjects With Essential Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine if there is greater blood pressure reduction using ramipril or hydrochlorothiazide alone or ramipril and hydrochlorothiazide together.

Study identification

NCT ID
NCT00355589
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
Not listed

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 2006
Primary completion
Feb 28, 2007
Completion
Feb 28, 2007
Last update posted
Oct 9, 2012

2006 – 2007

United States locations

U.S. sites
60
U.S. states
21
U.S. cities
54
Facility City State ZIP Site status
Cahaba Research Inc. Birmingham Alabama 35242
Clinical Research Associates Huntsville Alabama 35801
Pulmonary Associates Glendale Arizona 85306
Impact Clinical Trials Beverly Hills California 90211
Lovelace Scientific Resources, Inc. Beverly Hills California 90211
Associated Pharmaceutical Research Center, Inc. Buena Park California 90620
Marin Endocrine Care and Research Greenbrae California 94904
Memorial Research Medical Clinic Long Beach California 90806
The Intermed Group; Samaritan Medical Tower Los Angeles California 90017
National Research Institute Los Angeles California 90057
Clinical Trials Research Roseville California 95661
Bayview Research Group Studio City California 91604
Viking Clinical Research Temecula California 92591
University of Connecticut Health Center Farmington Connecticut 06030
Clinical Research of West Florida, Inc. Clearwater Florida 33765
Clinical Research of South Florida Coral Gables Florida 33134
University Clinical Research Deland, Inc. DeLand Florida 32720
South Florida Clinical Research Center Hollywood Florida 33023
Innovative Research of West Florida Largo Florida 33770
International Research Associates, LLC Miami Florida 33156
Lifespan Research Foundation Miami Florida 33186
Sun Coast Clinical Research New Port Richey Florida 34652
Renstar Medical Research Ocala Florida 34471
Suncoast Clinical Research, Inc. Palm Harbor Florida 34684
University Clinical Research, Inc. Pembroke Pines Florida 33024
Lovelace Scientific Resources Sarasota Florida 34233
Metabolic Research Institute, Inc. West Palm Beach Florida 33401
Executive Health and Research Associates, Inc. Atlanta Georgia 30342
Cedar Crosse Research Center Chicago Illinois 60607
James R. Herron, MD, Ltd. Chicago Illinois 60610
Clinical Investigation Specialists, Inc. Gurnee Illinois 60031
Midwest Institute for Clinical Research Indianapolis Indiana 46260
Michigan Institute of Medicine Livonia Michigan 48152
Medical Research Associates Traverse City Michigan 49684
Twin Cities Clinical Research Brooklyn Center Minnesota 55430
Advanced Biomedical Research of America Las Vegas Nevada 89123
Partners in Primary Care Voorhees Township New Jersey 08043
Cumberland Research Assocites, LLC Fayetteville North Carolina 28304
Unifour Medical Research Associates Hickory North Carolina 28601
Triangle Medical Research Associates Raleigh North Carolina 27609
The Lipid Center Statesville North Carolina 28677
Lyndhurst Gynecologic Associates, PA Winston-Salem North Carolina 27103
Piedmont Medical Research Associates Winston-Salem North Carolina 27103
Sterling Research Group, Inc. Cincinnati Ohio 45219
Smith Clinical Research Marion Ohio 43302
Radiant Research - Mogadore Mogadore Ohio 44260
Lion Research Norman Oklahoma 73069
Medford Medical Clinic Research Dept. Medford Oregon 97504
Philadelphia Health Associates Philadelphia Pennsylvania 19146
Medical Research South Charleston South Carolina 29407
SC Clinical Research Center, LLC Columbia South Carolina 29201
Radiant Research - Greer Greer South Carolina 29651
MetaClin Research, Inc. Austin Texas 78704
Punzi Medical Center Carrollton Texas 75006
Research Across America Dallas Texas 75234
Radiant Research - San Antonio San Antonio Texas 78229
WellMed Medical Management San Antonio Texas 78229
Clinical Research Associates of Tidewater Norfolk Virginia 23507
The Chase Wellness Center, Inc Virginia Beach Virginia 23455
Radiant Research - Tacoma Lakewood Washington 98499

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00355589, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 9, 2012 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00355589 live on ClinicalTrials.gov.

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