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Completed Phase 3 Interventional

Ramipril and Hydrochlorothiazide Alone and in Combination for the Treatment of Essential Hypertension

ClinicalTrials.gov ID: NCT00355589

Public ClinicalTrials.gov record NCT00355589. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:35 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Multicenter, Parallel Study Evaluating the Efficacy and Safety of a Combination of Ramipril Plus Hydrochlorothiazide Versus the Component Monotherapies in Subjects With Essential Hypertension

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine if there is greater blood pressure reduction using ramipril or hydrochlorothiazide alone or ramipril and hydrochlorothiazide together.

Study identification

NCT ID
NCT00355589
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
Not listed

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 2006 (Type not available)
Primary completion
Mar 2007 (Actual)
Completion
Mar 2007 (Actual)
Last update posted
Oct 10, 2012

2006 – 2007

United States locations

U.S. sites
60
U.S. states
21
U.S. cities
54
Facility City State ZIP Site status
Cahaba Research Inc. Birmingham Alabama 35242 —
Clinical Research Associates Huntsville Alabama 35801 —
Pulmonary Associates Glendale Arizona 85306 —
Impact Clinical Trials Beverly Hills California 90211 —
Lovelace Scientific Resources, Inc. Beverly Hills California 90211 —
Associated Pharmaceutical Research Center, Inc. Buena Park California 90620 —
Marin Endocrine Care and Research Greenbrae California 94904 —
Memorial Research Medical Clinic Long Beach California 90806 —
The Intermed Group; Samaritan Medical Tower Los Angeles California 90017 —
National Research Institute Los Angeles California 90057 —
Clinical Trials Research Roseville California 95661 —
Bayview Research Group Studio City California 91604 —
Viking Clinical Research Temecula California 92591 —
University of Connecticut Health Center Farmington Connecticut 06030 —
Clinical Research of West Florida, Inc. Clearwater Florida 33765 —
Clinical Research of South Florida Coral Gables Florida 33134 —
University Clinical Research Deland, Inc. DeLand Florida 32720 —
South Florida Clinical Research Center Hollywood Florida 33023 —
Innovative Research of West Florida Largo Florida 33770 —
International Research Associates, LLC Miami Florida 33156 —
Lifespan Research Foundation Miami Florida 33186 —
Sun Coast Clinical Research New Port Richey Florida 34652 —
Renstar Medical Research Ocala Florida 34471 —
Suncoast Clinical Research, Inc. Palm Harbor Florida 34684 —
University Clinical Research, Inc. Pembroke Pines Florida 33024 —
Lovelace Scientific Resources Sarasota Florida 34233 —
Metabolic Research Institute, Inc. West Palm Beach Florida 33401 —
Executive Health and Research Associates, Inc. Atlanta Georgia 30342 —
Cedar Crosse Research Center Chicago Illinois 60607 —
James R. Herron, MD, Ltd. Chicago Illinois 60610 —
Clinical Investigation Specialists, Inc. Gurnee Illinois 60031 —
Midwest Institute for Clinical Research Indianapolis Indiana 46260 —
Michigan Institute of Medicine Livonia Michigan 48152 —
Medical Research Associates Traverse City Michigan 49684 —
Twin Cities Clinical Research Brooklyn Center Minnesota 55430 —
Advanced Biomedical Research of America Las Vegas Nevada 89123 —
Partners in Primary Care Voorhees Township New Jersey 08043 —
Cumberland Research Assocites, LLC Fayetteville North Carolina 28304 —
Unifour Medical Research Associates Hickory North Carolina 28601 —
Triangle Medical Research Associates Raleigh North Carolina 27609 —
The Lipid Center Statesville North Carolina 28677 —
Lyndhurst Gynecologic Associates, PA Winston-Salem North Carolina 27103 —
Piedmont Medical Research Associates Winston-Salem North Carolina 27103 —
Sterling Research Group, Inc. Cincinnati Ohio 45219 —
Smith Clinical Research Marion Ohio 43302 —
Radiant Research - Mogadore Mogadore Ohio 44260 —
Lion Research Norman Oklahoma 73069 —
Medford Medical Clinic Research Dept. Medford Oregon 97504 —
Philadelphia Health Associates Philadelphia Pennsylvania 19146 —
Medical Research South Charleston South Carolina 29407 —
SC Clinical Research Center, LLC Columbia South Carolina 29201 —
Radiant Research - Greer Greer South Carolina 29651 —
MetaClin Research, Inc. Austin Texas 78704 —
Punzi Medical Center Carrollton Texas 75006 —
Research Across America Dallas Texas 75234 —
Radiant Research - San Antonio San Antonio Texas 78229 —
WellMed Medical Management San Antonio Texas 78229 —
Clinical Research Associates of Tidewater Norfolk Virginia 23507 —
The Chase Wellness Center, Inc Virginia Beach Virginia 23455 —
Radiant Research - Tacoma Lakewood Washington 98499 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00355589, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 10, 2012 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00355589 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →