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Terminated Phase 2 Interventional Results available

Minocycline for the Treatment of Decreased Mental Function in HIV-Infected Adults

ClinicalTrials.gov ID: NCT00361257

Public ClinicalTrials.gov record NCT00361257. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 24, 2026, 4:52 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II, Randomized, Placebo-Controlled, Double-Blind Study of Minocycline in the Treatment of HIV-Associated Cognitive Impairment

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine the effectiveness of minocycline, an antibiotic, in lessening the decreased mental function sometimes caused by anti-HIV drugs.

Study identification

NCT ID
NCT00361257
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Enrollment
107 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2007
Primary completion
Dec 31, 2009
Completion
Dec 31, 2009
Last update posted
Feb 4, 2016

2007 – 2010

United States locations

U.S. sites
16
U.S. states
14
U.S. cities
16
Facility City State ZIP Site status
UCLA-David Geffen School of Medicine Los Angeles California 90035 —
University of California San Diego California 92103 —
University of Colorado Health Science Center Denver Colorado 80262-3706 —
The Ponce de Leon Ctr. CRS Atlanta Georgia 30308 —
Northwestern University CRS Chicago Illinois 60611 —
Johns Hopkins School of Medicine Baltimore Maryland 21287-8106 —
Massachusetts General Hospital, Division of Infectious Diseases Boston Massachusetts 02114 —
Henry Ford Hosp. CRS Detroit Michigan 48202 —
Washington University St Louis Missouri 63108-2138 —
NYU Med Ctr, Dept of Medicine New York New York 10016 —
1101 University of Rochester Medical Center, Division of Infectious Diseases Rochester New York 14642 —
University of North Carolina, AIDS Clinical Trials Unit Chapel Hill North Carolina 27514 —
The Research and Education Group - Portland CRS Portland Oregon 97209 —
University of Pennsylvania, ACTU Philadelphia Pennsylvania 19104 —
Virginia Commonwealth Univ. Medical Ctr. CRS Richmond Virginia 23219 —
Univ of Washington, Harborview Medical Ctr Seattle Washington 98104 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00361257, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 4, 2016 · Synced Sep 24, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00361257 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →