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Completed Phase 3 Interventional Results available

Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Cancer

ClinicalTrials.gov ID: NCT00363129

Public ClinicalTrials.gov record NCT00363129. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

The Use of Vitamin E for Prevention of Chemotherapy Induced Peripheral Neuropathy: A Phase III Double-Blind Placebo Controlled Study

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Vitamin E may prevent peripheral neuropathy caused by chemotherapy in patients with cancer. It is not yet known whether vitamin E is more effective than a placebo in preventing peripheral neuropathy caused by chemotherapy in patients receiving chemotherapy for cancer. PURPOSE: This randomized phase III trial is studying vitamin E to see how well it works compared with placebo in preventing peripheral neuropathy caused by chemotherapy in patients receiving chemotherapy for cancer.

Study identification

NCT ID
NCT00363129
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Enrollment
207 participants

Conditions and interventions

Interventions

Dietary Supplement · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 2006 (Type not available)
Primary completion
Dec 2010 (Actual)
Completion
Aug 2014 (Actual)
Last update posted
Jul 6, 2016

2006 – 2014

United States locations

U.S. sites
69
U.S. states
8
U.S. cities
49
Facility City State ZIP Site status
St. Joseph Medical Center Bloomington Illinois 61701 —
Graham Hospital Canton Illinois 61520 —
Memorial Hospital Carthage Illinois 62321 —
Eureka Community Hospital Eureka Illinois 61530 —
Galesburg Clinic, PC Galesburg Illinois 61401 —
Galesburg Cottage Hospital Galesburg Illinois 61401 —
Mason District Hospital Havana Illinois 62644 —
Hopedale Medical Complex Hopedale Illinois 61747 —
Joliet Oncology-Hematology Associates, Limited - West Joliet Illinois 60435 —
Kewanee Hospital Kewanee Illinois 61443 —
BroMenn Regional Medical Center Normal Illinois 61761 —
Community Cancer Center Normal Illinois 61761 —
Community Hospital of Ottawa Ottawa Illinois 61350 —
Oncology Hematology Associates of Central Illinois, PC - Ottawa Ottawa Illinois 61350 —
CCOP - Illinois Oncology Research Association Peoria Illinois 61615 —
Oncology Hematology Associates of Central Illinois, PC - Peoria Peoria Illinois 61615 —
Perry Memorial Hospital Princeton Illinois 61356 —
Carle Cancer Center at Carle Foundation Hospital Urbana Illinois 61801 —
CCOP - Carle Cancer Center Urbana Illinois 61801 —
Saint Anthony Memorial Health Centers Michigan City Indiana 46360 —
McCreery Cancer Center at Ottumwa Regional Ottumwa Iowa 52501 —
Siouxland Hematology-Oncology Associates, LLP Sioux City Iowa 51101 —
St. Luke's Regional Medical Center Sioux City Iowa 51104 —
Saint Joseph Mercy Cancer Center Ann Arbor Michigan 48106-0995 —
CCOP - Michigan Cancer Research Consortium Ann Arbor Michigan 48106 —
Oakwood Cancer Center at Oakwood Hospital and Medical Center Dearborn Michigan 48123-2500 —
Genesys Hurley Cancer Institute Flint Michigan 48503 —
Van Elslander Cancer Center at St. John Hospital and Medical Center Grosse Pointe Woods Michigan 48236 —
Foote Memorial Hospital Jackson Michigan 49201 —
Sparrow Regional Cancer Center Lansing Michigan 48912-1811 —
Seton Cancer Institute at Saint Mary's - Saginaw Saginaw Michigan 48601 —
St. John Macomb Hospital Warren Michigan 48093 —
Fairview Ridges Hospital Burnsville Minnesota 55337 —
Mercy and Unity Cancer Center at Mercy Hospital Coon Rapids Minnesota 55433 —
Fairview Southdale Hospital Edina Minnesota 55435 —
Mercy and Unity Cancer Center at Unity Hospital Fridley Minnesota 55432 —
Hutchinson Area Health Care Hutchinson Minnesota 55350 —
Meeker County Memorial Hospital Lichfield Minnesota 55355 —
Immanuel St. Joseph's Mankato Minnesota 56002 —
HealthEast Cancer Care at St. John's Hospital Maplewood Minnesota 55109 —
Minnesota Oncology Hematology, PA - Maplewood Maplewood Minnesota 55109 —
Virginia Piper Cancer Institute at Abbott - Northwestern Hospital Minneapolis Minnesota 55407 —
Hennepin County Medical Center - Minneapolis Minneapolis Minnesota 55415 —
CCOP - Metro-Minnesota Saint Louis Park Minnesota 55416 —
HealthEast Cancer Care at St. Joseph's Hospital Saint Paul Minnesota 55102 —
United Hospital Saint Paul Minnesota 55102 —
St. Francis Cancer Center at St. Francis Medical Center Shakopee Minnesota 55379 —
HealthEast Cancer Care at Woodwinds Health Campus Woodbury Minnesota 55125 —
Minnesota Oncology Hematology, PA - Woodbury Woodbury Minnesota 55125 —
Bismarck Cancer Center Bismarck North Dakota 58501 —
Medcenter One Hospital Cancer Care Center Bismarck North Dakota 58501 —
Mid Dakota Clinic, PC Bismarck North Dakota 58501 —
Adena Regional Medical Center Chillicothe Ohio 45601 —
Riverside Methodist Hospital Cancer Care Columbus Ohio 43214-3998 —
CCOP - Columbus Columbus Ohio 43215 —
Grant Riverside Cancer Services Columbus Ohio 43215 —
Mount Carmel Health - West Hospital Columbus Ohio 43222 —
Doctors Hospital at Ohio Health Columbus Ohio 43228 —
Grady Memorial Hospital Delaware Ohio 43015 —
Fairfield Medical Center Lancaster Ohio 43130 —
Strecker Cancer Center at Marietta Memorial Hospital Marietta Ohio 45750 —
Licking Memorial Cancer Care Program at Licking Memorial Hospital Newark Ohio 43055 —
Mercy Medical Center Springfield Ohio 45504 —
Community Hospital of Springfield and Clark County Springfield Ohio 45505 —
Mount Carmel St. Ann's Cancer Center Westerville Ohio 43081 —
Genesis - Good Samaritan Hospital Zanesville Ohio 43701 —
Avera Cancer Institute Sioux Falls South Dakota 57105 —
Medical X-Ray Center, PC Sioux Falls South Dakota 57105 —
Sanford Cancer Center at Sanford USD Medical Center Sioux Falls South Dakota 57117-5039 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00363129, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 6, 2016 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00363129 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →