Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain

ClinicalTrials.gov ID: NCT00366431

Public ClinicalTrials.gov record NCT00366431. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 22, 2026, 11:15 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction in Subjects With Chronic Non-Malignant Pain

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary purpose of the protocol is to evaluate the safety, efficacy, and tolerability of MOA-728 in subjects with Opioid-Induced Bowel Dysfunction (OIBD) with associated chronic non-malignant pain.

Study identification

NCT ID: NCT00366431
Recruitment status: Completed
Study type: Interventional
Phase: Phase 2
Lead sponsor: Bausch Health Americas, Inc.; Industry
Enrollment: 420 participants

Conditions and interventions

Conditions

Constipation

Interventions

MOA-728 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Aug 2006 (Type not available)
Primary completion: Not listed
Completion: Mar 2007 (Actual)
Last update posted: Nov 25, 2019

2006 – 2007

United States locations

U.S. sites: 67
U.S. states: 26
U.S. cities: 56

Facility	City	State	ZIP	Site status
Not listed	Birmingham	Alabama	35215	—
Not listed	Birmingham	Alabama	35244	—
Not listed	Mobile	Alabama	36608	—
Not listed	Phoenix	Arizona	85029	—
Not listed	Tucson	Arizona	85710	—
Not listed	Tucson	Arizona	85712	—
Not listed	Tucson	Arizona	85741	—
Not listed	Hot Springs	Arkansas	71913	—
Not listed	Anaheim	California	92801	—
Not listed	Anaheim	California	92805	—
Not listed	Bakersfield	California	93311	—
Not listed	Foothill Ranch	California	92610	—
Not listed	Garden Grove	California	92843	—
Not listed	Los Gatos	California	95032	—
Not listed	Orange	California	92869	—
Not listed	Sacramento	California	95831	—
Not listed	San Diego	California	92108	—
Not listed	San Diego	California	92120	—
Not listed	San Diego	California	92121	—
Not listed	Trumbull	Connecticut	06611	—
Not listed	Hollywood	Florida	33021	—
Not listed	Jacksonville	Florida	32216	—
Not listed	Jupiter	Florida	33458	—
Not listed	Largo	Florida	33770	—
Not listed	Miami	Florida	33173	—
Not listed	Miami	Florida	33180	—
Not listed	Ocala	Florida	34471	—
Not listed	Ormond Beach	Florida	32174	—
Not listed	Saint Cloud	Florida	34769	—
Not listed	Tampa	Florida	33607	—
Not listed	West Palm Beach	Florida	33401	—
Not listed	Dawsonville	Georgia	30534	—
Not listed	Marietta	Georgia	30060	—
Not listed	Marietta	Georgia	30066	—
Not listed	Bloomington	Illinois	61701	—
Not listed	Chicago	Illinois	60610	—
Not listed	Indianapolis	Indiana	46250	—
Not listed	Elkridge	Maryland	21075	—
Not listed	Boston	Massachusetts	02115	—
Not listed	Brockton	Massachusetts	02301	—
Not listed	Saginaw	Michigan	48602	—
Not listed	Traverse City	Michigan	49684	—
Not listed	Picayune	Mississippi	39466	—
Not listed	Independence	Missouri	64055	—
Not listed	Missoula	Montana	59808	—
Not listed	Omaha	Nebraska	68114	—
Not listed	Reno	Nevada	89502	—
Not listed	Haddon Heights	New Jersey	08035	—
Not listed	Albuquerque	New Mexico	87102	—
Not listed	Great Neck	New York	11023	—
Not listed	Lake Success	New York	11042	—
Not listed	Charlotte	North Carolina	28210	—
Not listed	Winston-Salem	North Carolina	27103	—
Not listed	Cincinnati	Ohio	45219	—
Not listed	Cincinnati	Ohio	45224	—
Not listed	Dayton	Ohio	45439	—
Not listed	Clinton	Oklahoma	73601	—
Not listed	Chattanooga	Tennessee	37404	—
Not listed	Beaumont	Texas	77701	—
Not listed	Colleyville	Texas	76034	—
Not listed	San Antonio	Texas	78205	—
Not listed	San Antonio	Texas	78209	—
Not listed	San Antonio	Texas	78238	—
Not listed	Alexandria	Virginia	22304	—
Not listed	Christiansburg	Virginia	24073	—
Not listed	Norfolk	Virginia	23502	—
Not listed	Richmond	Virginia	23229	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT00366431, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Nov 25, 2019 · Synced Oct 22, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00366431 live on ClinicalTrials.gov.

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