Intravenous And Oral Casopitant (GW679769) For The Prevention Of Chemotherapy Induced Nausea And Vomiting
Public ClinicalTrials.gov record NCT00366834. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicenter, Randomized, Double-Blind, Active Controlled, Parallel Group Study of the Safety and Efficacy of the Intravenous and Oral Formulations of the Neurokinin-1 Receptor Antagonist Casopitant (GW679769) in Combination With Ondansetron and Dexamethasone for the Prevention of Nausea
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase III trial designed to demonstrate that casopitant (GW679769) plus dexamethasone and ondansetron is more effective in the prevention of vomiting than dexamethasone and ondansetron alone following the administration of moderately emetogenic chemotherapy.
Study identification
- NCT ID
- NCT00366834
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,840 participants
Conditions and interventions
Interventions
- Casopitant (GW679769) oral tablets Drug
- Casopitant (GW679769) intravenous Drug
- Dexamethasone intravenous Drug
- Ondansetron oral tablets Drug
- placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2006 (Type not available)
- Primary completion
- Oct 2007 (Actual)
- Completion
- Oct 2009 (Actual)
- Last update posted
- Sep 10, 2012
2006 – 2009
United States locations
- U.S. sites
- 86
- U.S. states
- 33
- U.S. cities
- 81
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Birmingham | Alabama | 35209 | — |
| GSK Investigational Site | Birmingham | Alabama | 35233 | — |
| GSK Investigational Site | Glendale | Arizona | 85304 | — |
| GSK Investigational Site | Fayetteville | Arkansas | 72703 | — |
| GSK Investigational Site | Hot Springs | Arkansas | 71913 | — |
| GSK Investigational Site | Jonesboro | Arkansas | 72401 | — |
| GSK Investigational Site | Concord | California | 94520 | — |
| GSK Investigational Site | Fountain Valley | California | 92708 | — |
| GSK Investigational Site | Fresno | California | 93710 | — |
| GSK Investigational Site | Greenbrae | California | 94904-2007 | — |
| GSK Investigational Site | La Verne | California | 91750 | — |
| GSK Investigational Site | Los Angeles | California | 90057 | — |
| GSK Investigational Site | Orange | California | 92868 | — |
| GSK Investigational Site | Poway | California | 92064 | — |
| GSK Investigational Site | San Diego | California | 92121 | — |
| GSK Investigational Site | Soquel | California | 95073 | — |
| GSK Investigational Site | Norwich | Connecticut | 06360 | — |
| GSK Investigational Site | Washington D.C. | District of Columbia | 20010 | — |
| GSK Investigational Site | Boynton Beach | Florida | 33435 | — |
| GSK Investigational Site | Brooksville | Florida | 34613 | — |
| GSK Investigational Site | Fort Lauderdale | Florida | 33316 | — |
| GSK Investigational Site | Fort Lauderdale | Florida | 33328 | — |
| GSK Investigational Site | Inverness | Florida | 34452 | — |
| GSK Investigational Site | Miami | Florida | 33179 | — |
| GSK Investigational Site | New Port Richey | Florida | 34652 | — |
| GSK Investigational Site | Tamarac | Florida | 33321 | — |
| GSK Investigational Site | Tampa | Florida | 33614 | — |
| GSK Investigational Site | West Palm Beach | Florida | 33401 | — |
| GSK Investigational Site | Augusta | Georgia | 30912 | — |
| GSK Investigational Site | Columbus | Georgia | 31904 | — |
| GSK Investigational Site | Lawrenceville | Georgia | 30045 | — |
| GSK Investigational Site | Centralia | Illinois | 62801 | — |
| GSK Investigational Site | Galesburg | Illinois | 61401 | — |
| GSK Investigational Site | Skokie | Illinois | 60076 | — |
| GSK Investigational Site | Evansville | Indiana | 47713 | — |
| GSK Investigational Site | Muncie | Indiana | 47303 | — |
| GSK Investigational Site | Terre Haute | Indiana | 47804 | — |
| GSK Investigational Site | Mason City | Iowa | 50401 | — |
| GSK Investigational Site | Hazard | Kentucky | 41701 | — |
| GSK Investigational Site | Lexington | Kentucky | 40503 | — |
| GSK Investigational Site | Alexandria | Louisiana | 71301 | — |
| GSK Investigational Site | Baton Rouge | Louisiana | 70809 | — |
| GSK Investigational Site | Metairie | Louisiana | 70006 | — |
| GSK Investigational Site | Baltimore | Maryland | 21229-5299 | — |
| GSK Investigational Site | Baltimore | Maryland | 21237 | — |
| GSK Investigational Site | Pittsfield | Massachusetts | 01201 | — |
| GSK Investigational Site | Worcester | Massachusetts | 01608 | — |
| GSK Investigational Site | Clinton Township | Michigan | 48038 | — |
| GSK Investigational Site | Free Soil | Michigan | 49411 | — |
| GSK Investigational Site | Saint Joseph | Michigan | 49085 | — |
| GSK Investigational Site | Troy | Michigan | 48085 | — |
| GSK Investigational Site | Hattiesburg | Mississippi | 39401 | — |
| GSK Investigational Site | Tupelo | Mississippi | 38801 | — |
| GSK Investigational Site | Jefferson City | Missouri | 65109 | — |
| GSK Investigational Site | Rolla | Missouri | 65401 | — |
| GSK Investigational Site | St Louis | Missouri | 63141 | — |
| GSK Investigational Site | Billings | Montana | 59101 | — |
| GSK Investigational Site | Great Falls | Montana | 59405 | — |
| GSK Investigational Site | Denville | New Jersey | 07834 | — |
| GSK Investigational Site | Newark | New Jersey | 07112 | — |
| GSK Investigational Site | Somerville | New Jersey | 08876 | — |
| GSK Investigational Site | Sparta | New Jersey | 07871 | — |
| GSK Investigational Site | Albuquerque | New Mexico | 87109 | — |
| GSK Investigational Site | Buffalo | New York | 14215 | — |
| GSK Investigational Site | Durham | North Carolina | 27710 | — |
| GSK Investigational Site | Winston-Salem | North Carolina | 27103 | — |
| GSK Investigational Site | Bismarck | North Dakota | 58501 | — |
| GSK Investigational Site | Akron | Ohio | 44304 | — |
| GSK Investigational Site | Bethlehem | Pennsylvania | 18015 | — |
| GSK Investigational Site | Hershey | Pennsylvania | 17033 | — |
| GSK Investigational Site | Sayre | Pennsylvania | 18840 | — |
| GSK Investigational Site | Mt. Pleasant | South Carolina | 29464 | — |
| GSK Investigational Site | Sumter | South Carolina | 29150 | — |
| GSK Investigational Site | Corpus Christi | Texas | 78412 | — |
| GSK Investigational Site | Corpus Christi | Texas | 78463-3069 | — |
| GSK Investigational Site | Dallas | Texas | 75237 | — |
| GSK Investigational Site | Richardson | Texas | 75080 | — |
| GSK Investigational Site | Logan | Utah | 84341 | — |
| GSK Investigational Site | Ogden | Utah | 84403 | — |
| GSK Investigational Site | Burlington | Vermont | 05401 | — |
| GSK Investigational Site | Everett | Washington | 98201 | — |
| GSK Investigational Site | Spokane | Washington | 99204 | — |
| GSK Investigational Site | Tacoma | Washington | 98405 | — |
| GSK Investigational Site | Huntington | West Virginia | 25701 | — |
| GSK Investigational Site | Huntington | West Virginia | 25705 | — |
| GSK Investigational Site | Madison | Wisconsin | 53717 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 137 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00366834, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 10, 2012 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00366834 live on ClinicalTrials.gov.