ClinicalTrials.gov record
Efficacy, Safety, and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations
ClinicalTrials.gov ID: NCT00368108
Public ClinicalTrials.gov record NCT00368108. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study of the Efficacy, Safety, and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations
Study identification
- NCT ID
- NCT00368108
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Eisai Inc.
- Industry
- Enrollment
- 752 participants
Conditions and interventions
Conditions
Interventions
- 2 mg perampanel Drug
- 4 mg perampanel Drug
- placebo comparator Drug
Drug
Eligibility (public fields only)
- Age range
- 30 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2006
- Primary completion
- Dec 31, 2007
- Completion
- Dec 31, 2007
- Last update posted
- May 19, 2013
2006 – 2008
United States locations
- U.S. sites
- 99
- U.S. states
- 36
- U.S. cities
- 85
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| North Alabama Neuroscience Research Associates | Huntsville | Alabama | 35801 | — |
| Pivotal Research Centers | Peoria | Arizona | 85381 | — |
| Mayo Clinic Arizona | Scottsdale | Arizona | 85259 | — |
| Northwest NeuroSpecialists, PLLC | Tucson | Arizona | 85741-3537 | — |
| Clinical Trials Inc. | Little Rock | Arkansas | 72205 | — |
| UAMS Department of Neurology | Little Rock | Arkansas | 72205 | — |
| The Parkinson's and Movement Disorder Institute | Fountain Valley | California | 92708 | — |
| Margolin Brain Institute | Fresno | California | 93720 | — |
| University of California Medical Center - Irvine | Irvine | California | 92697 | — |
| Coastal Neurological Group | La Jolla | California | 92037 | — |
| Scripps Clinic | La Jolla | California | 92037 | — |
| University of California at San Diego - Department of Neurology | La Jolla | California | 92161 | — |
| Loma Linda University | Loma Linda | California | 92354 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| Pacific Neuroscience Medical Group, Inc. | Oxnard | California | 93030 | — |
| University of California San Francisco Medical Center | San Francisco | California | 94143-1969 | — |
| The Parkinson's Institute | Sunnyvale | California | 94089 | — |
| Mile High Research Center | Denver | Colorado | 80218 | — |
| University Of Colorado | Denver | Colorado | 80262 | — |
| Colorado Neurology | Englewood | Colorado | 80113 | — |
| Associated Neurologists, PC - Danbury | Danbury | Connecticut | 06810 | — |
| Hartford Hospital | Hartford | Connecticut | 06106 | — |
| Molecular Neuroimaging, LLC | New Haven | Connecticut | 06511 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007-2197 | — |
| Parkinson's Disease and Movement Disorder Center of Boca Raton | Boca Raton | Florida | 33486 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| Sunrise Clinical Research | Hollywood | Florida | 33021 | — |
| University of Florida - Department of Neurology | Jacksonville | Florida | 32209 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Miami Research Associates | Miami | Florida | 33173 | — |
| Palm Beach Neurological Center | Palm Beach Gardens | Florida | 33418 | — |
| Gil, Ramon A. | Port Charlotte | Florida | 33952 | — |
| Suncoast Neuroscience Associates, Inc. | St. Petersburg | Florida | 33701 | — |
| University Of South Florida Movement Disorders Clinic | Tampa | Florida | 33606 | — |
| Cleveland Clinic Florida - Weston | Weston | Florida | 33331 | — |
| Emory University | Atlanta | Georgia | 30329 | — |
| Medical College of Georgia | Augusta | Georgia | 30912 | — |
| Dekalb Neurology Associates, LLC/DNA Research | Decatur | Georgia | 30033 | — |
| Northwestern University Medical School | Chicago | Illinois | 60611 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Fort Wayne Neurological Center | Fort Wayne | Indiana | 46805 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University Of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas | Kansas City | Kansas | 66160 | — |
| University Of Kentucky | Lexington | Kentucky | 40536-0284 | — |
| Kentucky Neuroscience Research | Louisville | Kentucky | 40202 | — |
| LSUHSC-Shreveport | Shreveport | Louisiana | 71103 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Parkinson's and Movement Disorders Center of Maryland | Elkridge | Maryland | 21075 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| Harvard Vanguard Medical Associates | Boston | Massachusetts | 02215 | — |
| Quest Research Institute | Bingham Farms | Michigan | 48025 | — |
| The Clinical Neurosciences Center | Southfield | Michigan | 48034 | — |
| Northern Michigan Neurology | Traverse City | Michigan | 49684 | — |
| Struthers Parkinson's Center | Golden Valley | Minnesota | 55427 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Creighton University - Department of Neurology | Omaha | Nebraska | 68131 | — |
| University of Nevada School of Medicine | Las Vegas | Nevada | 89102 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| University of Medicine and Dentistry of New Jersey | New Brunswick | New Jersey | 08901 | — |
| Albany Medical College | Albany | New York | 12205 | — |
| Parkinson's Disease and Movement Disorder Center of Long Island | Commack | New York | 11725 | — |
| New York University Medical Center | Forest Hills | New York | 11375 | — |
| North Shore Medical Center | Manhasset | New York | 11030 | — |
| The Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Columbia University | New York | New York | 10032 | — |
| University of Rochester - Neurology Clinic | Rochester | New York | 14618 | — |
| Asheville Neurology Specialists. PA | Asheville | North Carolina | 28806 | — |
| Asheville Neurology Specialists | Asheville | North Carolina | 28806 | — |
| Duke University | Durham | North Carolina | 27705 | — |
| Raleigh Neurology Associates, P.A. | Raleigh | North Carolina | 27607-6520 | — |
| Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| Neurology Specialists, Inc. | Dayton | Ohio | 45408 | — |
| The University of Toledo College of Medicine | Toledo | Ohio | 43614 | — |
| University of Oklahoma - Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Crozer Medical Center | Upland | Pennsylvania | 19013 | — |
| Lankenau Hospital | Wynnewood | Pennsylvania | 19096-3425 | — |
| Semmes Murphey Neurology and Spine Institute | Memphis | Tennessee | 38103 | — |
| Radiant Research - Dallas North | Dallas | Texas | 75231 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Agape' Medical Center, Inc. | Lubbock | Texas | 79410 | — |
| Bhupesh Dihenia, MD, PA | Lubbock | Texas | 79410 | — |
| Neurology Associates | San Antonio | Texas | 78258 | — |
| Fletcher Allen Health Care | Burlington | Vermont | 05401 | — |
| Hunter Holmes McGuire | Richmond | Virginia | 23249 | — |
| Neurology and Neurosurgery Associates of Tacoma, PLLC | Tacoma | Washington | 98405 | — |
| Capitol Neurology | Charleston | West Virginia | 25301 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Wisconsin Institute for Neurologic and Sleep Disorders | Milwaukee | Wisconsin | 53233 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00368108, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 19, 2013 · Synced May 15, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00368108 live on ClinicalTrials.gov.