Bevacizumab, Radiation Therapy, and Cisplatin in Treating Patients With Previously Untreated Locally Advanced Cervical Cancer
Public ClinicalTrials.gov record NCT00369122. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE II STUDY OF BEVACIZUMAB IN COMBINATION WITH DEFINITIVE RADIOTHERAPY AND CISPLATIN CHEMOTHERAPY IN UNTREATED PATIENTS WITH LOCALLY ADVANCED CERVICAL CARCINOMA
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase II trial is studying how well giving bevacizumab together with radiation therapy and cisplatin works in treating patients with previously untreated locally advanced cervical cancer. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of cervical cancer by blocking blood flow to the tumor. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving bevacizumab together with radiation therapy and cisplatin may kill more tumor cells.
Study identification
- NCT ID
- NCT00369122
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 60 participants
Conditions and interventions
Conditions
Interventions
- Bevacizumab Biological
- Cisplatin Drug
- External Beam Radiation Therapy Radiation
- Internal Radiation Therapy Radiation
Biological · Drug · Radiation
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 11, 2006 (Actual)
- Primary completion
- Jun 4, 2010 (Actual)
- Completion
- Dec 15, 2016 (Actual)
- Last update posted
- Mar 20, 2018
2006 – 2016
United States locations
- U.S. sites
- 103
- U.S. states
- 24
- U.S. cities
- 76
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | 91505 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| University of Colorado | Denver | Colorado | 80217-3364 | — |
| Baptist MD Anderson Cancer Center | Jacksonville | Florida | 32207 | — |
| Integrated Community Oncology Network-Southside Cancer Center | Jacksonville | Florida | 32207 | — |
| University of Florida Health Science Center - Jacksonville | Jacksonville | Florida | 32209 | — |
| Baptist Medical Center South | Jacksonville | Florida | 32258 | — |
| Integrated Community Oncology Network-Florida Cancer Center Beaches | Jacksonville Beach | Florida | 32250 | — |
| 21st Century Oncology-Orange Park | Orange Park | Florida | 32073 | — |
| UF Cancer Center at Orlando Health | Orlando | Florida | 32806 | — |
| 21st Century Oncology-Palatka | Palatka | Florida | 32177 | — |
| Bay Medical Center | Panama City | Florida | 32401 | — |
| Integrated Community Oncology Network-Flager Cancer Center | Saint Augustine | Florida | 32086 | — |
| Grady Health System | Atlanta | Georgia | 30303 | — |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Northwest Community Hospital | Arlington Heights | Illinois | 60005 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| John H Stroger Jr Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Franciscan St. James Health-Olympia Fields Campus | Olympia Fields | Illinois | 60461 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61603 | — |
| Saint Vincent Anderson Regional Hospital/Cancer Center | Anderson | Indiana | 46016 | — |
| Franciscan Saint Francis Health-Beech Grove | Beech Grove | Indiana | 46107 | — |
| Saint Vincent Hospital and Health Care Center | Indianapolis | Indiana | 46260 | — |
| Reid Health | Richmond | Indiana | 47374 | — |
| Providence Medical Center | Kansas City | Kansas | 66112 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| Radiation Oncology Practice Corporation Southwest | Overland Park | Kansas | 66210 | — |
| Saint Luke's South Hospital | Overland Park | Kansas | 66213 | — |
| Shawnee Mission Medical Center-KCCC | Shawnee Mission | Kansas | 66204 | — |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | — |
| Norton Suburban Hospital and Medical Campus | Louisville | Kentucky | 40207 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | — |
| Borgess Medical Center | Kalamazoo | Michigan | 49001 | — |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Cape Radiation Oncology | Cape Girardeau | Missouri | 63703 | — |
| Centerpoint Medical Center LLC | Independence | Missouri | 64057 | — |
| Truman Medical Center | Kansas City | Missouri | 64108 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Radiation Oncology Practice Corporation South | Kansas City | Missouri | 64114 | — |
| Saint Joseph Health Center | Kansas City | Missouri | 64114 | — |
| North Kansas City Hospital | Kansas City | Missouri | 64116 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Radiation Oncology Practice Corporation - North | Kansas City | Missouri | 64154 | — |
| Saint Luke's East - Lee's Summit | Lee's Summit | Missouri | 64086 | — |
| Liberty Radiation Oncology Center | Liberty | Missouri | 64068 | — |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | — |
| CHI Health Good Samaritan | Kearney | Nebraska | 68847 | — |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| Saint Barnabas Medical Center | Livingston | New Jersey | 07039 | — |
| Monmouth Medical Center | Long Branch | New Jersey | 07740 | — |
| Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital | New Brunswick | New Jersey | 08903 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| New York-Presbyterian/Brooklyn Methodist Hospital | Brooklyn | New York | 11215 | — |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Highland Hospital | Rochester | New York | 14620 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Summa Akron City Hospital/Cooper Cancer Center | Akron | Ohio | 44304 | — |
| Summa Barberton Hospital | Barberton | Ohio | 44203 | — |
| Grandview Hospital | Dayton | Ohio | 45405 | — |
| Good Samaritan Hospital - Dayton | Dayton | Ohio | 45406 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| Samaritan North Health Center | Dayton | Ohio | 45415 | — |
| Veteran Affairs Medical Center | Dayton | Ohio | 45428 | — |
| Blanchard Valley Hospital | Findlay | Ohio | 45840 | — |
| Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | 45005-1066 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| Cancer Care Center, Incorporated | Salem | Ohio | 44460 | — |
| Upper Valley Medical Center | Troy | Ohio | 45373 | — |
| Clinton Memorial Hospital | Wilmington | Ohio | 45177 | — |
| Cancer Treatment Center | Wooster | Ohio | 44691 | — |
| Wright-Patterson Medical Center | Wright-Patterson Air Force Base | Ohio | 45433-5529 | — |
| Greene Memorial Hospital | Xenia | Ohio | 45385 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301 | — |
| Einstein Medical Center Philadelphia | Philadelphia | Pennsylvania | 19141 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| Main Line Health NCORP | Wynnewood | Pennsylvania | 19096 | — |
| Wellmont Holston Valley Hospital and Medical Center | Kingsport | Tennessee | 37660 | — |
| M D Anderson Cancer Center | Houston | Texas | 77030 | — |
| American Fork Hospital / Huntsman Intermountain Cancer Center | American Fork | Utah | 84003 | — |
| Sandra L Maxwell Cancer Center | Cedar City | Utah | 84720 | — |
| Logan Regional Hospital | Logan | Utah | 84321 | — |
| Cottonwood Hospital Medical Center | Murray | Utah | 84107 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| McKay-Dee Hospital Center | Ogden | Utah | 84403 | — |
| Utah Valley Regional Medical Center | Provo | Utah | 84604 | — |
| Intermountain Health Care | Salt Lake City | Utah | 84103 | — |
| Utah Cancer Specialists-Salt Lake City | Salt Lake City | Utah | 84106 | — |
| Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | 84112 | — |
| LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Dixie Medical Center Regional Cancer Center | St. George | Utah | 84770 | — |
| Southwest VA Regional Cancer Center | Norton | Virginia | 24273 | — |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima | Washington | 98902 | — |
| Gundersen Lutheran Medical Center | La Crosse | Wisconsin | 54601 | — |
| Froedtert and the Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00369122, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 20, 2018 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00369122 live on ClinicalTrials.gov.