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Completed Phase 3 Interventional

Clevidipine in the Treatment of Patients With Severe Hypertension (VELOCITY)

ClinicalTrials.gov ID: NCT00369837

Public ClinicalTrials.gov record NCT00369837. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 12, 2026, 4:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Evaluation of the Effect of Ultrashort-Acting Clevidipine in the Treatment of Patients With Severe Hypertension (VELOCITY)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study was to determine the safety of clevidipine for treating severely elevated blood pressure, defined as systolic (SBP) \>180 mmHg and/or diastolic blood pressure (DBP) \>115 mmHg assessed on 2 successive occasions 15 minutes apart at baseline, in patients with or without major organ injury, particularly with respect to controlled dose adjustment to desired effect and prolonged continuous infusion. Enrollment of patients into the study was to continue until the target goal of 100 patients with at least 18 hours of continuous clevidipine treatment, including a minimum of 50 patients with acute or chronic end-organ injury, was met.

Study identification

NCT ID
NCT00369837
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
The Medicines Company
Industry
Enrollment
131 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2006
Primary completion
Dec 31, 2006
Completion
Jan 31, 2007
Last update posted
May 21, 2014

2006 – 2007

United States locations

U.S. sites
14
U.S. states
10
U.S. cities
13
Facility City State ZIP Site status
Jackson Hospital Montgomery Alabama 36106
VA Medical Center W. LA Los Angeles California 90073
The George Washington University Medical Center Washington D.C. District of Columbia 20037
Louisiana State University Medical Center/Charity Hospital New Orleans Louisiana 70118
Critical Care Research Center at Louisiana State University Health Sciences Center Shreveport Louisiana 71103
Good Samaritan Hospital Baltimore Maryland 21239
Duke University Medical Center Durham North Carolina 27710
Metrohealth Medical Center Cleveland Ohio 44109
The Cleveland Clinic Cleveland Ohio 44195
The Toledo Hospital Toledo Ohio 43606
Providence Heart & Vascular Institute, d/b/a Providence St. Vincent Medical Center Portland Oregon 97225
Hamot Shock Trauma Erie Pennsylvania 16550
Pennsylvania Hospital Philadelphia Pennsylvania 19107
The University of Texas Health Science Center Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00369837, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 21, 2014 · Synced Sep 12, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00369837 live on ClinicalTrials.gov.

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