Study of Apixaban for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery
Public ClinicalTrials.gov record NCT00371683. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-Blind Active-Controlled (Enoxaparin), Parallel-Group, Multi-Center Study to Evaluate the Safety and Efficacy of Oral Apixaban in Subjects Undergoing Elective Total Knee Replacement Surgery
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to learn if apixaban can prevent blood clots in the leg (deep vein Thrombosis \[DVT\]) and lung (pulmonary embolism \[PE\]) that sometimes occur after knee replacement surgery and to learn how apixaban compares to enoxaparin (Lovenox®) for preventing these clots. The safety of apixaban will also be studied.
Study identification
- NCT ID
- NCT00371683
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 3,608 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2006 (Type not available)
- Primary completion
- May 2008 (Actual)
- Completion
- May 2008 (Actual)
- Last update posted
- Dec 30, 2015
2006 – 2008
United States locations
- U.S. sites
- 25
- U.S. states
- 11
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Capstone Clinical Trials, Inc | Birmingham | Alabama | 35205 | — |
| Capstone Clinical Trials, Inc | Birmingham | Alabama | 35209 | — |
| West Alabama Research, Inc. | Tuscaloosa | Alabama | 35406 | — |
| Martin Bowen Hefley Orthopedics | Little Rock | Arkansas | 72205 | — |
| Colorado Orthopedic Consultants, Pc | Aurora | Colorado | 80012 | — |
| Colorado Joint Replacement | Denver | Colorado | 80210 | — |
| Jdpmedical Research | Denver | Colorado | 80230 | — |
| Orhtopaedic Physicians Of Colorado, P.C. | Englewood | Colorado | 80113 | — |
| Orthopedics Assocs Of Hartford | Hartford | Connecticut | 06106 | — |
| Anthony S. Unger, Md | Washington D.C. | District of Columbia | 20006 | — |
| Bay Pines Va Medical Center | Bay Pines | Florida | 33744 | — |
| Pab Clinical Research | Brandon | Florida | 33511 | — |
| Jacksonville Center For Clinical Research | Jacksonville | Florida | 32216 | — |
| Mark W. Hollmann, Md | Orange City | Florida | 32763 | — |
| Jewett Orthopaedic Clinic | Winter Park | Florida | 32789 | — |
| Atlanta Knee And Sports Medicine | Decatur | Georgia | 30033 | — |
| Americana Orthopedics | Boise | Idaho | 83702 | — |
| Intermountain Orthopaedics | Boise | Idaho | 83702 | — |
| Bluegrass Orthopaedics/Bmr | Lexington | Kentucky | 40509 | — |
| Charleston Orthopaedic Assocs. | Charleston | South Carolina | 29414 | — |
| Kelsey Seybold Clinic | Houston | Texas | 77025 | — |
| Bone & Joint Clinic Of Houston | Houston | Texas | 77030 | — |
| Gill Orthopedic Center | Lubbock | Texas | 79410 | — |
| Robert R. King, Md | Lubbock | Texas | 79410 | — |
| Unlimited Research | San Antonio | Texas | 78217 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 82 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00371683, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 30, 2015 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00371683 live on ClinicalTrials.gov.