ClinicalTrials.gov record
Tykerb Evaluation After Chemotherapy (TEACH): Lapatinib Versus Placebo In Women With Early-Stage Breast Cancer
ClinicalTrials.gov ID: NCT00374322
Public ClinicalTrials.gov record NCT00374322. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Multicenter, Placebo-controlled Study of Adjuvant Lapatinib (GW572016) in Women With Early-Stage ErbB2 Overexpressing Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study was designed to evaluate and compare the safety and efficacy of an oral dual tyrosine kinase inhibitor, lapatinib, versus placebo in women with early-stage ErbB2-overexpressing breast cancer who have completed their primary neoadjuvant or adjuvant chemotherapy and have no clinical or radiographic evidence of disease.
Study identification
- NCT ID
- NCT00374322
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 3,166 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2006 (Type not available)
- Primary completion
- Sep 2011 (Actual)
- Completion
- Jul 2013 (Actual)
- Last update posted
- Aug 18, 2014
2006 – 2013
United States locations
- U.S. sites
- 103
- U.S. states
- 33
- U.S. cities
- 94
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Tuscaloosa | Alabama | 35406 | — |
| GSK Investigational Site | Phoenix | Arizona | 85012 | — |
| GSK Investigational Site | Sedona | Arizona | 86336 | — |
| GSK Investigational Site | Tucson | Arizona | 85715 | — |
| GSK Investigational Site | Fayetteville | Arkansas | 72703 | — |
| GSK Investigational Site | Jonesboro | Arkansas | 72401 | — |
| GSK Investigational Site | Little Rock | Arkansas | 72205 | — |
| GSK Investigational Site | Anaheim | California | 92801 | — |
| GSK Investigational Site | Bakersfield | California | 93309 | — |
| GSK Investigational Site | Gilroy | California | 95020 | — |
| GSK Investigational Site | La Jolla | California | 92037 | — |
| GSK Investigational Site | La Verne | California | 91750 | — |
| GSK Investigational Site | Palm Springs | California | 92262 | — |
| GSK Investigational Site | Rancho Mirage | California | 92270 | — |
| GSK Investigational Site | Denver | Colorado | 80220 | — |
| GSK Investigational Site | Fairfield | Connecticut | 06824 | — |
| GSK Investigational Site | Norwalk | Connecticut | 06856 | — |
| GSK Investigational Site | Torrington | Connecticut | 06790 | — |
| GSK Investigational Site | Washington D.C. | District of Columbia | 20007 | — |
| GSK Investigational Site | Washington D.C. | District of Columbia | 20010 | — |
| GSK Investigational Site | Boca Raton | Florida | 33428 | — |
| GSK Investigational Site | Boynton Beach | Florida | 33437 | — |
| GSK Investigational Site | Gainesville | Florida | 32605 | — |
| GSK Investigational Site | New Port Richey | Florida | 34655 | — |
| GSK Investigational Site | Ocala | Florida | 34474 | — |
| GSK Investigational Site | Orlando | Florida | 32806 | — |
| GSK Investigational Site | Plantation | Florida | 33324 | — |
| GSK Investigational Site | Port Saint Lucie | Florida | 34952 | — |
| GSK Investigational Site | Augusta | Georgia | 30901 | — |
| GSK Investigational Site | Marietta | Georgia | 30060 | — |
| GSK Investigational Site | Chicago | Illinois | 60611-2906 | — |
| GSK Investigational Site | Chicago | Illinois | 60611 | — |
| GSK Investigational Site | Joliet | Illinois | 60435 | — |
| GSK Investigational Site | Park Ridge | Illinois | 60068 | — |
| GSK Investigational Site | Indianapolis | Indiana | 46219 | — |
| GSK Investigational Site | Ames | Iowa | 50010 | — |
| GSK Investigational Site | Sioux City | Iowa | 51101-1733 | — |
| GSK Investigational Site | Wichita | Kansas | 67214 | — |
| GSK Investigational Site | Louisville | Kentucky | 40245 | — |
| GSK Investigational Site | Marrero | Louisiana | 70072 | — |
| GSK Investigational Site | Scarborough | Maine | 4074 | — |
| GSK Investigational Site | Bethesda | Maryland | 20817 | — |
| GSK Investigational Site | Boston | Massachusetts | 02114 | — |
| GSK Investigational Site | Danvers | Massachusetts | 01923 | — |
| GSK Investigational Site | Newton | Massachusetts | 02462 | — |
| GSK Investigational Site | Kalamazoo | Michigan | 49048 | — |
| GSK Investigational Site | Duluth | Minnesota | 55805 | — |
| GSK Investigational Site | Edina | Minnesota | 55435 | — |
| GSK Investigational Site | Minneapolis | Minnesota | 55404 | — |
| GSK Investigational Site | Robbinsdale | Minnesota | 55422 | — |
| GSK Investigational Site | Columbia | Missouri | 65201 | — |
| GSK Investigational Site | Kansas City | Missouri | 64118 | — |
| GSK Investigational Site | Saint Joseph | Missouri | 64507 | — |
| GSK Investigational Site | St Louis | Missouri | 63109 | — |
| GSK Investigational Site | St Louis | Missouri | 63141 | — |
| GSK Investigational Site | Hooksett | New Hampshire | 03106 | — |
| GSK Investigational Site | Cherry Hill | New Jersey | 08003 | — |
| GSK Investigational Site | Morristown | New Jersey | 07962 | — |
| GSK Investigational Site | Paramus | New Jersey | 07652 | — |
| GSK Investigational Site | Sparta | New Jersey | 07871 | — |
| GSK Investigational Site | Albany | New York | 12206 | — |
| GSK Investigational Site | East Setauket | New York | 11733 | — |
| GSK Investigational Site | Mount Kisco | New York | 10590 | — |
| GSK Investigational Site | New York | New York | 10003 | — |
| GSK Investigational Site | New York | New York | 10016 | — |
| GSK Investigational Site | Rochester | New York | 14623 | — |
| GSK Investigational Site | Charleston | North Carolina | 29406 | — |
| GSK Investigational Site | Gastonia | North Carolina | 28054 | — |
| GSK Investigational Site | Greensboro | North Carolina | 27403 | — |
| GSK Investigational Site | Hickory | North Carolina | 28602 | — |
| GSK Investigational Site | Cleveland | Ohio | 44106 | — |
| GSK Investigational Site | Cleveland | Ohio | 44195 | — |
| GSK Investigational Site | Columbus | Ohio | 43215 | — |
| GSK Investigational Site | Middletown | Ohio | 45042 | — |
| GSK Investigational Site | Drexel Hill | Pennsylvania | 19026 | — |
| GSK Investigational Site | Philadelphia | Pennsylvania | 19107 | — |
| GSK Investigational Site | Charleston | South Carolina | 29414 | — |
| GSK Investigational Site | Chattanooga | Tennessee | 37403 | — |
| GSK Investigational Site | Germantown | Tennessee | 38138 | — |
| GSK Investigational Site | Memphis | Tennessee | 38120 | — |
| GSK Investigational Site | Austin | Texas | 78705 | — |
| GSK Investigational Site | Austin | Texas | 78759 | — |
| GSK Investigational Site | Bedford | Texas | 76022 | — |
| GSK Investigational Site | Dallas | Texas | 75230 | — |
| GSK Investigational Site | Dallas | Texas | 75231 | — |
| GSK Investigational Site | Dallas | Texas | 75246 | — |
| GSK Investigational Site | Duncanville | Texas | 75137 | — |
| GSK Investigational Site | El Paso | Texas | 79902 | — |
| GSK Investigational Site | Fort Worth | Texas | 76104 | — |
| GSK Investigational Site | Houston | Texas | 77024 | — |
| GSK Investigational Site | Houston | Texas | 77030 | — |
| GSK Investigational Site | Round Rock | Texas | 78681 | — |
| GSK Investigational Site | San Antonio | Texas | 78229 | — |
| GSK Investigational Site | Tyler | Texas | 75702 | — |
| GSK Investigational Site | Waco | Texas | 76712 | — |
| GSK Investigational Site | Ogden | Utah | 84403 | — |
| GSK Investigational Site | Chesapeake | Virginia | 23320 | — |
| GSK Investigational Site | Fairfax | Virginia | 22031 | — |
| GSK Investigational Site | Richlands | Virginia | 24641 | — |
| GSK Investigational Site | Kirkland | Washington | — | — |
| GSK Investigational Site | Seattle | Washington | 98104 | — |
| GSK Investigational Site | Vancouver | Washington | 98684 | — |
| GSK Investigational Site | Yakima | Washington | 98902 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 336 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00374322, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 18, 2014 · Synced Oct 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00374322 live on ClinicalTrials.gov.