A Study of Mycophenolate Mofetil (CellCept) in Management of Patients With Lupus Nephritis.
Public ClinicalTrials.gov record NCT00377637. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Randomized, Active Controlled, Parallel Group, Multi-center Trial to Assess the Efficacy and Safety of Mycophenolate Mofetil (MMF) in Inducing Response and Maintaining Remission in Subjects With Lupus Nephritis.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This 2 arm study assessed the efficacy of Mycophenolate Mofetil (MMF; CellCept) compared to cyclophosphamide in inducing a response in patients with lupus nephritis, and the long term efficacy of MMF compared to azathioprine in maintaining remission and renal function. Patients were randomized to receive either MMF (1.5 g twice daily \[bid\]) or cyclophosphamide (0.5-1.0 g/m\^2 in monthly pulses) in the induction phase. Those patients meeting criteria for response were re-randomized for entry into the maintenance phase, to receive either MMF (1 g bid) or azathioprine (2 mg/kg/day).
Study identification
- NCT ID
- NCT00377637
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 370 participants
Conditions and interventions
Conditions
Interventions
- Mycophenolate mofetil (MMF) Drug
- Cyclophosphamide Drug
- Azathioprine Drug
- Placebo to Azathioprine Drug
- Placebo to Mycophenolate mofetil Drug
- Corticosteroid Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2005 (Type not available)
- Primary completion
- Mar 2007 (Actual)
- Completion
- Mar 2010 (Actual)
- Last update posted
- Dec 6, 2011
2005 – 2010
United States locations
- U.S. sites
- 28
- U.S. states
- 16
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Huntsville | Alabama | 35801 | — |
| Not listed | La Jolla | California | 92037 | — |
| Not listed | Los Angeles | California | 90095 | — |
| Not listed | San Francisco | California | 94143 | — |
| Not listed | San Leandro | California | 94578 | — |
| Not listed | Torrance | California | 90502 | — |
| Not listed | Miami | Florida | 33136 | — |
| Not listed | Atlanta | Georgia | 30303 | — |
| Not listed | Chicago | Illinois | 60611 | — |
| Not listed | Chicago | Illinois | 60637 | — |
| Not listed | Baltimore | Maryland | 21205 | — |
| Not listed | Boston | Massachusetts | 02115 | — |
| Not listed | Ann Arbor | Michigan | 48109-0358 | — |
| Not listed | Columbia | Missouri | 65212 | — |
| Not listed | Brooklyn | New York | 11203 | — |
| Not listed | Lake Success | New York | 11042 | — |
| Not listed | New York | New York | 10003 | — |
| Not listed | New York | New York | 10021 | — |
| Not listed | New York | New York | 10032 | — |
| Not listed | Chapel Hill | North Carolina | 27599-7280 | — |
| Not listed | Durham | North Carolina | 27710 | — |
| Not listed | Cleveland | Ohio | 44136 | — |
| Not listed | Columbus | Ohio | 43210 | — |
| Not listed | Oklahoma City | Oklahoma | 73104 | — |
| Not listed | Philadelphia | Pennsylvania | 19104 | — |
| Not listed | Pittsburgh | Pennsylvania | 15213 | — |
| Not listed | Charleston | South Carolina | 29425 | — |
| Not listed | Dallas | Texas | 75390 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 80 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00377637, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 6, 2011 · Synced Oct 16, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00377637 live on ClinicalTrials.gov.