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Completed Phase 2 Interventional Results available

Trabectedin in Treating Patients With Advanced, Persistent, or Recurrent Leiomyosarcoma of the Uterus

ClinicalTrials.gov ID: NCT00379145

Public ClinicalTrials.gov record NCT00379145. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 9:23 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Evaluation of Trabectedin (Yondelis, R279741) in the Treatment of Advanced, Persistent, or Recurrent Uterine Leiomyosarcomas

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

RATIONALE: Drugs used in chemotherapy, such as trabectedin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase II trial is studying how well trabectedin works in treating patients with advanced, persistent, or recurrent leiomyosarcoma of the uterus.

Study identification

NCT ID
NCT00379145
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Gynecologic Oncology Group
Network
Enrollment
20 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
Female
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 2007 (Type not available)
Primary completion
Jan 2012 (Actual)
Completion
Not listed
Last update posted
Dec 12, 2017

Started 2007

United States locations

U.S. sites
32
U.S. states
18
U.S. cities
28
Facility City State ZIP Site status
USC/Norris Comprehensive Cancer Center and Hospital Los Angeles California 90089-9181 —
Helen and Harry Gray Cancer Center at Hartford Hospital Hartford Connecticut 06102-5037 —
George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus New Britain Connecticut 06050 —
Washington Cancer Institute at Washington Hospital Center Washington D.C. District of Columbia 20010 —
MBCCOP - Medical College of Georgia Cancer Center Augusta Georgia 30912 —
Central Georgia Gynecologic Oncology Macon Georgia 31201 —
Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center Savannah Georgia 31403-3089 —
Robert H. Lurie Comprehensive Cancer Center at Northwestern University Chicago Illinois 60611-3013 —
Hinsdale Hematology Oncology Associates Hinsdale Illinois 60521 —
St. Vincent Indianapolis Hospital Indianapolis Indiana 46260 —
Holden Comprehensive Cancer Center at University of Iowa Iowa City Iowa 52242-1002 —
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore Maryland 21231-2410 —
West Michigan Cancer Center Kalamazoo Michigan 49007-3731 —
St. John's Regional Health Center Springfield Missouri 65804 —
Women's Cancer Center - Lake Mead Las Vegas Nevada 89102 —
University of New Mexico Cancer Center Albuquerque New Mexico 87131-5636 —
SUNY Downstate Medical Center Brooklyn New York 11203 —
Memorial Sloan-Kettering Cancer Center New York New York 10021 —
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill Chapel Hill North Carolina 27599-7295 —
Blumenthal Cancer Center at Carolinas Medical Center Charlotte North Carolina 28232-2861 —
Presbyterian Cancer Center at Presbyterian Hospital Charlotte North Carolina 28233-3549 —
Duke Comprehensive Cancer Center Durham North Carolina 27710 —
Case Comprehensive Cancer Center Cleveland Ohio 44106-5065 —
MetroHealth Cancer Care Center at MetroHealth Medical Center Cleveland Ohio 44109 —
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195 —
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center Columbus Ohio 43210-1240 —
Riverside Methodist Hospital Cancer Care Columbus Ohio 43214-3998 —
David L. Rike Cancer Center at Miami Valley Hospital Dayton Ohio 45409 —
Lake/University Ireland Cancer Center Mentor Ohio 44060 —
Oklahoma University Cancer Institute Oklahoma City Oklahoma 73104 —
Rosenfeld Cancer Center at Abington Memorial Hospital Abington Pennsylvania 19001 —
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center Madison Wisconsin 53792-6164 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00379145, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 12, 2017 · Synced Oct 24, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00379145 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →