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Terminated Phase 2 Interventional Results available

Azacitidine and Erythropoietin Versus Azacitidine Alone for Patients With Low-Risk Myelodysplastic Syndromes

ClinicalTrials.gov ID: NCT00379912

Public ClinicalTrials.gov record NCT00379912. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 7:00 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Randomized Trial With A Modified Dose & Schedule of Subcutaneously Administered Azacitidine & Erythropoietin v Azacitidine Alone in Patients With Low-Risk Myelodysplastic Syndromes (Less Than 11% Marrow & Peripheral Blood Blasts)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This trial is designed to explore a modified dose and schedule of azacitidine in order to more effectively address the needs of patients with low-risk myelodysplastic syndromes (MDS), i.e., to alter the natural history of the disease without excessive toxicity or burden. The administration of erythropoietin is designed to influence the differentiation of primitive hematopoietic cells in which azacitidine has reversed the abnormal phenotype to red blood cells for patients in whom inadequate production of red blood cells is the major clinical issue.

Study identification

NCT ID
NCT00379912
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Larry Cripe, MD
Other
Enrollment
15 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2006
Primary completion
Nov 30, 2008
Completion
Nov 30, 2008
Last update posted
Feb 13, 2018

2006 – 2008

United States locations

U.S. sites
9
U.S. states
4
U.S. cities
7
Facility City State ZIP Site status
Medical & Surgical Specialists, LLC Galesburg Illinois 61401
Indiana University Cancer Center Indianapolis Indiana 46202
Quality Cancer Center (MCGOP) Indianapolis Indiana 46202
Arnett Cancer Care Lafayette Indiana 47904
Horizon Oncology Center Lafayette Indiana 47905
Medical Consultants, P.C. Muncie Indiana 47303
Northern Indiana Cancer Research Consortium South Bend Indiana 46601
Center for Hematology-Oncology of S Michigan Jackson Michigan 49201
Methodist Cancer Center Omaha Nebraska 68114

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00379912, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 13, 2018 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00379912 live on ClinicalTrials.gov.

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