ClinicalTrials.gov record
Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer
ClinicalTrials.gov ID: NCT00381706
Public ClinicalTrials.gov record NCT00381706. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 16, 2026, 12:44 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized Phase II Study of ECF-C, IC-C, or FOLFOX-C in Metastatic Esophageal and GE Junction Cancer
Study identification
- NCT ID
- NCT00381706
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Alliance for Clinical Trials in Oncology
- Other
- Enrollment
- 245 participants
Conditions and interventions
Conditions
Interventions
- ECF Drug
- FOLFOX Drug
- IC Drug
- cetuximab Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 14, 2006
- Primary completion
- Mar 31, 2011
- Completion
- Oct 14, 2014
- Last update posted
- Sep 28, 2021
2006 – 2014
United States locations
- U.S. sites
- 227
- U.S. states
- 28
- U.S. cities
- 161
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Tunnell Cancer Center at Beebe Medical Center | Lewes | Delaware | 19958 | — |
| CCOP - Christiana Care Health Services | Newark | Delaware | 19713 | — |
| Lombardi Comprehensive Cancer Center at Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Rush-Copley Cancer Care Center | Aurora | Illinois | 60504 | — |
| St. Joseph Medical Center | Bloomington | Illinois | 61701 | — |
| Graham Hospital | Canton | Illinois | 61520 | — |
| Memorial Hospital | Carthage | Illinois | 62321 | — |
| University of Chicago Cancer Research Center | Chicago | Illinois | 60637-1470 | — |
| Decatur Memorial Hospital Cancer Care Institute | Decatur | Illinois | 62526 | — |
| Eureka Community Hospital | Eureka | Illinois | 61530 | — |
| Evanston Hospital | Evanston | Illinois | 60201-1781 | — |
| Galesburg Clinic, PC | Galesburg | Illinois | 61401 | — |
| Galesburg Cottage Hospital | Galesburg | Illinois | 61401 | — |
| Ingalls Cancer Care Center at Ingalls Memorial Hospital | Harvey | Illinois | 60426 | — |
| Mason District Hospital | Havana | Illinois | 62644 | — |
| Hopedale Medical Complex | Hopedale | Illinois | 61747 | — |
| Joliet Oncology-Hematology Associates, Limited - West | Joliet | Illinois | 60435 | — |
| McDonough District Hospital | Macomb | Illinois | 61455 | — |
| BroMenn Regional Medical Center | Normal | Illinois | 61761 | — |
| Community Cancer Center | Normal | Illinois | 61761 | — |
| Community Hospital of Ottawa | Ottawa | Illinois | 61350 | — |
| Oncology Hematology Associates of Central Illinois, PC - Ottawa | Ottawa | Illinois | 61350 | — |
| Cancer Treatment Center at Pekin Hospital | Pekin | Illinois | 61554 | — |
| Proctor Hospital | Peoria | Illinois | 61614 | — |
| CCOP - Illinois Oncology Research Association | Peoria | Illinois | 61615 | — |
| Oncology Hematology Associates of Central Illinois, PC - Peoria | Peoria | Illinois | 61615 | — |
| Methodist Medical Center of Illinois | Peoria | Illinois | 61636 | — |
| OSF St. Francis Medical Center | Peoria | Illinois | 61637 | — |
| Illinois Valley Community Hospital | Peru | Illinois | 61354 | — |
| Perry Memorial Hospital | Princeton | Illinois | 61356 | — |
| Swedish-American Regional Cancer Center | Rockford | Illinois | 61104-2315 | — |
| St. Margaret's Hospital | Spring Valley | Illinois | 61362 | — |
| Regional Cancer Center at Memorial Medical Center | Springfield | Illinois | 62781-0001 | — |
| Carle Cancer Center at Carle Foundation Hospital | Urbana | Illinois | 61801 | — |
| CCOP - Carle Cancer Center | Urbana | Illinois | 61801 | — |
| Elkhart General Hospital | Elkhart | Indiana | 46515 | — |
| Fort Wayne Medical Oncology and Hematology | Fort Wayne | Indiana | 46845 | — |
| Indiana University Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202-5289 | — |
| William N. Wishard Memorial Hospital | Indianapolis | Indiana | 46202 | — |
| Howard Community Hospital | Kokomo | Indiana | 46904 | — |
| Center for Cancer Therapy at LaPorte Hospital and Health Services | La Porte | Indiana | 46350 | — |
| Saint Anthony Memorial Health Centers | Michigan City | Indiana | 46360 | — |
| CCOP - Northern Indiana CR Consortium | South Bend | Indiana | 46601 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Saint Joseph Regional Medical Center | South Bend | Indiana | 46617 | — |
| South Bend Clinic | South Bend | Indiana | 46617 | — |
| McFarland Clinic, PC | Ames | Iowa | 50010 | — |
| Hematology Oncology Associates of the Quad Cities | Bettendorf | Iowa | 52722 | — |
| Cedar Rapids Oncology Associates | Cedar Rapids | Iowa | 52403 | — |
| Mercy Regional Cancer Center at Mercy Medical Center | Cedar Rapids | Iowa | 52403 | — |
| Mercy Capitol Hospital | Des Moines | Iowa | 50307 | — |
| CCOP - Iowa Oncology Research Association | Des Moines | Iowa | 50309 | — |
| John Stoddard Cancer Center at Iowa Methodist Medical Center | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates at John Stoddard Cancer Center | Des Moines | Iowa | 50309 | — |
| Medical Oncology and Hematology Associates at Mercy Cancer Center | Des Moines | Iowa | 50314 | — |
| Mercy Cancer Center at Mercy Medical Center - Des Moines | Des Moines | Iowa | 50314 | — |
| John Stoddard Cancer Center at Iowa Lutheran Hospital | Des Moines | Iowa | 50316 | — |
| Holden Comprehensive Cancer Center at University of Iowa | Iowa City | Iowa | 52242-1002 | — |
| Mercy Cancer Center at Mercy Medical Center - North Iowa | Mason City | Iowa | 50401 | — |
| McCreery Cancer Center at Ottumwa Regional | Ottumwa | Iowa | 52501 | — |
| Siouxland Hematology-Oncology Associates, LLP | Sioux City | Iowa | 51101 | — |
| Mercy Medical Center - Sioux City | Sioux City | Iowa | 51104 | — |
| St. Luke's Regional Medical Center | Sioux City | Iowa | 51104 | — |
| Medical Oncology and Hematology Associates - West Des Moines | West Des Moines | Iowa | 50266 | — |
| Hospital District Sixth of Harper County | Anthony | Kansas | 67003 | — |
| Cancer Center of Kansas, PA - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas, PA - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas, PA - El Dorado | El Dorado | Kansas | 67042 | — |
| Cancer Center of Kansas - Fort Scott | Fort Scott | Kansas | 66701 | — |
| Cancer Center of Kansas-Independence | Independence | Kansas | 67301 | — |
| Cancer Center of Kansas, PA - Kingman | Kingman | Kansas | 67068 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Southwest Medical Center | Liberal | Kansas | 67901 | — |
| Cancer Center of Kansas, PA - Newton | Newton | Kansas | 67114 | — |
| Menorah Medical Center | Overland Park | Kansas | 66209 | — |
| Cancer Center of Kansas, PA - Parsons | Parsons | Kansas | 67357 | — |
| Cancer Center of Kansas, PA - Pratt | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas, PA - Salina | Salina | Kansas | 67042 | — |
| Shawnee Mission Medical Center | Shawnee Mission | Kansas | 66204 | — |
| Cancer Center of Kansas, PA - Wellington | Wellington | Kansas | 67152 | — |
| Associates in Womens Health, PA - North Review | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas, PA - Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas, PA - Wichita | Wichita | Kansas | 67214 | — |
| CCOP - Wichita | Wichita | Kansas | 67214 | — |
| Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas, PA - Winfield | Winfield | Kansas | 67156 | — |
| CancerCare of Maine at Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Harry and Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center | Baltimore | Maryland | 21237 | — |
| Shore Regional Cancer Center at Memorial Hospital - Easton | Easton | Maryland | 21601 | — |
| Union Hospital of Cecil County | Elkton | Maryland | 21921 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Dana-Farber/Brigham and Women's Cancer Center | Boston | Massachusetts | 02115 | — |
| Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute | Boston | Massachusetts | 02115 | — |
| Lahey Clinic Medical Center - Burlington | Burlington | Massachusetts | 01805 | — |
| South Shore Hospital | South Weymouth | Massachusetts | 02190 | — |
| Baystate Regional Cancer Program at D'Amour Center for Cancer Care | Springfield | Massachusetts | 01199 | — |
| Saint Joseph Mercy Cancer Center | Ann Arbor | Michigan | 48106-0995 | — |
| CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | 48106 | — |
| Oakwood Cancer Center at Oakwood Hospital and Medical Center | Dearborn | Michigan | 48123-2500 | — |
| Green Bay Oncology, Limited - Escanaba | Escanaba | Michigan | 49431 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Grosse Pointe Woods | Michigan | 48236 | — |
| Dickinson County Healthcare System | Iron Mountain | Michigan | 49801 | — |
| Foote Memorial Hospital | Jackson | Michigan | 49201 | — |
| Borgess Medical Center | Kalamazoo | Michigan | 49001 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007-3731 | — |
| Bronson Methodist Hospital | Kalamazoo | Michigan | 49007 | — |
| Sparrow Regional Cancer Center | Lansing | Michigan | 48912-1811 | — |
| St. Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| St. Joseph Mercy Oakland | Pontiac | Michigan | 48341-2985 | — |
| Mercy Regional Cancer Center at Mercy Hospital | Port Huron | Michigan | 48060 | — |
| Seton Cancer Institute at Saint Mary's - Saginaw | Saginaw | Michigan | 48601 | — |
| Lakeland Regional Cancer Care Center - St. Joseph | Saint Joseph | Michigan | 49085 | — |
| Oncology Care Associates, PLLC | Saint Joseph | Michigan | 49085 | — |
| St. John Macomb Hospital | Warren | Michigan | 48093 | — |
| Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Mercy and Unity Cancer Center at Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Essentia Health - Duluth Clinic | Duluth | Minnesota | 55805-1983 | — |
| CCOP - Duluth | Duluth | Minnesota | 55805 | — |
| Miller - Dwan Medical Center | Duluth | Minnesota | 55805 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| Mercy and Unity Cancer Center at Unity Hospital | Fridley | Minnesota | 55432 | — |
| Hutchinson Area Health Care | Hutchinson | Minnesota | 55350 | — |
| Meeker County Memorial Hospital | Litchfield | Minnesota | 55355 | — |
| HealthEast Cancer Care at St. John's Hospital | Maplewood | Minnesota | 55109 | — |
| Minnesota Oncology - Maplewood | Maplewood | Minnesota | 55109 | — |
| Virginia Piper Cancer Institute at Abbott - Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center - Minneapolis | Minneapolis | Minnesota | 55415 | — |
| Veterans Affairs Medical Center - Minneapolis | Minneapolis | Minnesota | 55417 | — |
| Humphrey Cancer Center at North Memorial Outpatient Center | Robbinsdale | Minnesota | 55422-2900 | — |
| CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| Park Nicollet Cancer Center | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital Cancer Care Center | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| St. Francis Cancer Center at St. Francis Medical Center | Shakopee | Minnesota | 55379 | — |
| Ridgeview Medical Center | Waconia | Minnesota | 55387 | — |
| Minnesota Oncology - Woodbury | Woodbury | Minnesota | 55125 | — |
| Independence Regional Health Center | Independence | Missouri | 64050 | — |
| Truman Medical Center - Hospital Hill | Kansas City | Missouri | 64108 | — |
| Saint Luke's Cancer Institute at Saint Luke's Hospital | Kansas City | Missouri | 64111 | — |
| St. Joseph Medical Center | Kansas City | Missouri | 64114 | — |
| North Kansas City Hospital | Kansas City | Missouri | 64116 | — |
| Parvin Radiation Oncology | Kansas City | Missouri | 64116 | — |
| CCOP - Kansas City | Kansas City | Missouri | 64131 | — |
| Research Medical Center | Kansas City | Missouri | 64132 | — |
| Liberty Hospital | Liberty | Missouri | 64068 | — |
| Heartland Regional Medical Center | Saint Joseph | Missouri | 64506 | — |
| Missouri Baptist Cancer Center | St Louis | Missouri | 63131 | — |
| Arch Medical Services, Incorporated at Center for Cancer Care and Research | St Louis | Missouri | 63141 | — |
| CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | 68106 | — |
| Methodist Estabrook Cancer Center | Omaha | Nebraska | 68114 | — |
| Immanuel Medical Center | Omaha | Nebraska | 68122 | — |
| Alegant Health Cancer Center at Bergan Mercy Medical Center | Omaha | Nebraska | 68124 | — |
| Creighton University Medical Center | Omaha | Nebraska | 68131-2197 | — |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| CCOP - Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756-0002 | — |
| Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton | Marlton | New Jersey | 08053 | — |
| Newark Beth Israel Medical Center | Newark | New Jersey | 07112 | — |
| Frederick R. and Betty M. Smith Cancer Treatment Center | Sparta | New Jersey | 07871 | — |
| Cancer Institute of New Jersey at Cooper - Voorhees | Voorhees Township | New Jersey | 08043 | — |
| Fox Chase Virtua Health Cancer Program at Virtua West Jersey | Voorhees Township | New Jersey | 08043 | — |
| Veterans Affairs Medical Center - Buffalo | Buffalo | New York | 14215 | — |
| CCOP - Hematology-Oncology Associates of Central New York | East Syracuse | New York | 13057 | — |
| Charles R. Wood Cancer Center at Glens Falls Hospital | Glens Falls | New York | 12801 | — |
| Ralph Lauren Center for Cancer Care and Prevention | New York | New York | 10035 | — |
| Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | — |
| Our Lady of Mercy Medical Center Comprehensive Cancer Center | The Bronx | New York | 10466 | — |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Chapel Hill | North Carolina | 27599-7295 | — |
| Blumenthal Cancer Center at Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Wayne Memorial Hospital, Incorporated | Goldsboro | North Carolina | 27534 | — |
| Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| Kinston Medical Specialists | Kinston | North Carolina | 28501 | — |
| Summa Center for Cancer Care at Akron City Hospital | Akron | Ohio | 44309-2090 | — |
| Aultman Cancer Center at Aultman Hospital | Canton | Ohio | 44710-1799 | — |
| MetroHealth Cancer Care Center at MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210-1240 | — |
| St. Rita's Medical Center | Lima | Ohio | 45801 | — |
| Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest | Allentown | Pennsylvania | 18105 | — |
| St. Luke's Cancer Network at St. Luke's Hospital | Bethlehem | Pennsylvania | 18015 | — |
| Geisinger Cancer Institute at Geisinger Health | Danville | Pennsylvania | 17822-0001 | — |
| Dale and Frances Hughes Cancer Center at Pocono Medical Center | East Stroudsburg | Pennsylvania | 18301 | — |
| Geisinger Hazleton Cancer Center | Hazleton | Pennsylvania | 18201 | — |
| Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033-0850 | — |
| Lewistown Hospital | Lewistown | Pennsylvania | 17044 | — |
| Abramson Cancer Center of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104-4283 | — |
| Kimmel Cancer Center at Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | 19107-5541 | — |
| Joan Karnell Cancer Center at Pennsylvania Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Fox Chase Cancer Center - Philadelphia | Philadelphia | Pennsylvania | 19111-2497 | — |
| Frankford Hospital Cancer Center - Torresdale Campus | Philadelphia | Pennsylvania | 19114 | — |
| Hematology and Oncology Associates of Northeastern Pennsylvania | Scranton | Pennsylvania | 18508 | — |
| Geisinger Medical Group - Scenery Park | State College | Pennsylvania | 16801 | — |
| Mount Nittany Medical Center | State College | Pennsylvania | 16803 | — |
| Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center | Wilkes-Barre | Pennsylvania | 18711 | — |
| Mercy Hospital at Wilkes-Barre | Wilkes-Barre | Pennsylvania | 18765 | — |
| Susquehanna Cancer Center at Divine Providence Hospital | Williamsport | Pennsylvania | 17701 | — |
| McLeod Regional Medical Center | Florence | South Carolina | 29501 | — |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | — |
| Medical X-Ray Center, PC | Sioux Falls | South Dakota | 57105 | — |
| Sanford Cancer Center at Sanford USD Medical Center | Sioux Falls | South Dakota | 57117-5039 | — |
| Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center | Kingsport | Tennessee | 37662 | — |
| CCOP - Scott and White Hospital | Temple | Texas | 76508 | — |
| Mountainview Medical | Berlin Corners | Vermont | 05602 | — |
| Fletcher Allen Health Care - University Health Center Campus | Burlington | Vermont | 05401 | — |
| Danville Regional Medical Center | Danville | Virginia | 24541 | — |
| Southwest Virginia Regional Cancer Center at Wellmonth Health | Norton | Virginia | 24273 | — |
| Center for Cancer Treatment & Prevention at Sacred Heart Hospital | Eau Claire | Wisconsin | 54701 | — |
| Marshfield Clinic Cancer Care at Regional Cancer Center | Eau Claire | Wisconsin | 54701 | — |
| Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center | Green Bay | Wisconsin | 54301-3526 | — |
| Green Bay Oncology, Limited at St. Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| St. Mary's Hospital Medical Center - Green Bay | Green Bay | Wisconsin | 54303 | — |
| St. Vincent Hospital Regional Cancer Center | Green Bay | Wisconsin | 54307-3508 | — |
| Bay Area Cancer Care Center at Bay Area Medical Center | Marinette | Wisconsin | 54143 | — |
| Saint Joseph's Hospital | Marshfield | Wisconsin | 54449 | — |
| Medical Consultants, Limited | Milwaukee | Wisconsin | 53215 | — |
| Marshfield Clinic - Lakeland Center | Minocqua | Wisconsin | 54548 | — |
| Green Bay Oncology, Limited - Oconto Falls | Oconto Falls | Wisconsin | 54154 | — |
| Ministry Medical Group at Saint Mary's Hospital | Rhinelander | Wisconsin | 54501 | — |
| Marshfield Clinic - Indianhead Center | Rice Lake | Wisconsin | 54868 | — |
| Saint Michael's Hospital Cancer Center | Stevens Point | Wisconsin | 54481 | — |
| Green Bay Oncology, Limited - Sturgeon Bay | Sturgeon Bay | Wisconsin | 54235 | — |
| Marshfield Clinic - Wausau Center | Wausau | Wisconsin | 54401 | — |
| University of Wisconcin Cancer Center at Aspirus Wausau Hospital | Wausau | Wisconsin | 54401 | — |
| Marshfield Clinic - Weston Center | Weston | Wisconsin | 54476 | — |
| Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids | Wisconsin | 54494 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00381706, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2021 · Synced May 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00381706 live on ClinicalTrials.gov.