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Completed Phase 2 Interventional Results available

Phase II Trial of Aprepitant & Palonosetron for CINV Prevention w FOLFOX

ClinicalTrials.gov ID: NCT00381862

Public ClinicalTrials.gov record NCT00381862. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 7, 2026, 12:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-Center, Trial to Evaluate the Efficacy & Tolerability of Aprepitant and Palonosetron for the Prevention of CINV in Colorectal Cancer (CRC) Patients Receiving FOLFOX

Study identification

NCT ID
NCT00381862
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
OHSU Knight Cancer Institute
Other
Enrollment
54 participants

Conditions and interventions

Interventions

  • aprepitant Drug
  • dexamethasone Drug
  • fluorouracil Drug
  • irinotecan hydrochloride Drug
  • leucovorin calcium Drug
  • oxaliplatin Drug
  • palonosetron hydrochloride Drug
  • quality-of-life assessment Procedure

Drug · Procedure

Eligibility (public fields only)

Age range
18 Years to 120 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2006
Primary completion
Feb 29, 2008
Completion
Jun 30, 2008
Last update posted
Jun 11, 2017

2006 – 2008

United States locations

U.S. sites
6
U.S. states
6
U.S. cities
6
Facility City State ZIP Site status
St. Josephs/Cander Hospital Savannah Georgia 31405
Kaiser Permanente Hilo Hawaii 86720
Ingalls Memorial Hospital Harvey Illinois 60426
Kansas City Cancer Center Kansas City Missouri 64104
OHSU Knight Cancer Institute Portland Oregon 97239-3098
Texas A & M university / Scott and White Clinic Temple Texas 76508

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00381862, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 11, 2017 · Synced May 7, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00381862 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →