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Completed Phase 2 Interventional

Safety and Efficacy of Topically Applied CTA018 in Plaque Psoriasis

ClinicalTrials.gov ID: NCT00384098

Public ClinicalTrials.gov record NCT00384098. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 2:37 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Parallel-group, 4-arm, 12-week Study to Evaluate the Safety and Efficacy of Topically Applied CTA018 vs Vehicle for the Treatment of Adult Subjects With Chronic Plaque Psoriasis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Vitamin D and its analogs are currently widely used for the treatment of psoriasis. The study drug (CTA018) is a novel analog of vitamin D, and this Phase 2 study will investigate the efficacy and safety of CTA018 in the treatment of psoriasis. Patients with chronic plaque psoriasis will receive one of three doses of CTA018 cream or vehicle (no study drug) daily for 12 weeks.

Study identification

NCT ID
NCT00384098
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
OPKO Health, Inc.
Industry
Enrollment
140 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2006
Primary completion
Apr 30, 2007
Completion
Apr 30, 2007
Last update posted
Sep 28, 2014

2006 – 2007

United States locations

U.S. sites
16
U.S. states
12
U.S. cities
15
Facility City State ZIP Site status
Radiant Research Tucson Arizona 85710
Dermatology Research of Arkansas PLLC Little Rock Arkansas 72205
Northwestern University Chicago Illinois 60611
Radiant Research, Kansas City Overland Park Kansas 66215
Mass General/ Brigham & Women's Boston Massachusetts 02215
Department of Dermatology, Mayo Clinic Rochester Minnesota 55905
UMDNJ-Robert Wood Johnson Medical School New Brunswick New Jersey 08903
New York University Medical Center New York New York 10016
Mount Sinai School of Medicine New York New York 10029
Buffalo Medical Group PC Williamsville New York 14221
Wake Forest University Health Sciences Winston-Salem North Carolina 27157
Radiant Research Cincinnati Ohio 45249
University Hospitals of Cleveland Cleveland Ohio 44106
Paddington Testing Co. Philadelphia Pennsylvania 19103
Radiant Research Inc. Anderson South Carolina 29621
Palmetto Clinical Trial Services LLC Greenville South Carolina 29607

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00384098, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 28, 2014 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00384098 live on ClinicalTrials.gov.

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