First Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOX
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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT00384176. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.
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Official title
A Randomised, Double-blind, Multicentre Phase II/III Study to Compare the Efficacy of Cediranib (RECENTIN™, AZD2171) in Combination With 5-fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX), to the Efficacy of Bevacizumab in Combination With FOLFOX in Patients With Previously Untreated Metastatic Colorectal Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to see if Cediranib in combination with FOLFOX is effective in treating metastatic colorectal cancer and to see how it compares with Avastin (Bevacizumab) in combination with FOLFOX.
Study identification
- NCT ID
- NCT00384176
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 1,814 participants
Conditions and interventions
Conditions
Interventions
- Cediranib Drug
- Bevacizumab Drug
- 5-fluorouracil ( in FOLFOX) Drug
- Leucovorin (in FOLFOX) Drug
- Oxaliplatin (in FOLFOX) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 130 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 30, 2006 (Actual)
- Primary completion
- Nov 15, 2009 (Actual)
- Completion
- Aug 19, 2015 (Actual)
- Last update posted
- Apr 14, 2017
2006 – 2015
United States locations
- U.S. sites
- 44
- U.S. states
- 25
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Anniston | Alabama | — | — |
| Research Site | Birmingham | Alabama | — | — |
| Research Site | Casa Grande | Arizona | — | — |
| Research Site | Tucson | Arizona | — | — |
| Research Site | Hot Springs | Arkansas | — | — |
| Research Site | Palm Springs | California | — | — |
| Research Site | San Diego | California | — | — |
| Research Site | Fairfield | Connecticut | — | — |
| Research Site | Stamford | Connecticut | — | — |
| Research Site | Bay Pines | Florida | — | — |
| Research Site | Fort Meyers | Florida | — | — |
| Research Site | Port Saint Lucie | Florida | — | — |
| Research Site | Galesburg | Illinois | — | — |
| Research Site | Park Ridge | Illinois | — | — |
| Research Site | Quincy | Illinois | — | — |
| Research Site | Layfayette | Indiana | — | — |
| Research Site | New Albany | Indiana | — | — |
| Research Site | Alexandria | Louisiana | — | — |
| Research Site | Layfayette | Louisiana | — | — |
| Research Site | Hagerstown | Maryland | — | — |
| Research Site | Ann Arbor | Michigan | — | — |
| Research Site | Ypsilanti | Michigan | — | — |
| Research Site | St Louis | Missouri | — | — |
| Research Site | Great Falls | Montana | — | — |
| Research Site | Lincoln | Nebraska | — | — |
| Research Site | Summit | New Jersey | — | — |
| Research Site | Fresh Meadows | New York | — | — |
| Research Site | Northport | New York | — | — |
| Research Site | Rochester | New York | — | — |
| Research Site | Fayetteville | North Carolina | — | — |
| Research Site | New Bern | North Carolina | — | — |
| Research Site | Bismarck | North Dakota | — | — |
| Research Site | Cincinnati | Ohio | — | — |
| Research Site | Middletown | Ohio | — | — |
| Research Site | Zanesville | Ohio | — | — |
| Research Site | Coos Bay | Oregon | — | — |
| Research Site | Hilton Head Island | South Carolina | — | — |
| Research Site | Chattanooga | Tennessee | — | — |
| Research Site | Knoxville | Tennessee | — | — |
| Research Site | Nashville | Tennessee | — | — |
| Research Site | Austin | Texas | — | — |
| Research Site | White River Junction | Vermont | — | — |
| Research Site | Abingdon | Virginia | — | — |
| Research Site | Alexandria | Virginia | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 236 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00384176, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 14, 2017 · Synced Nov 14, 2026
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