Short Term Effects of PRX-03140 in Patients With Mild Alzheimer's Disease Being Treated With Aricept
Public ClinicalTrials.gov record NCT00384423. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Phase IIa Study to Assess the Short-Term Effects of PRX-03140 Alone and in Combination With Donepezil in Subjects With Mild Alzheimer's Disease.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PRX-03140 administered orally once daily for 14 days in subjects with mild Alzheimer's Disease who are using a stable, well-tolerated 10 mg dose of Aricept (donepezil) but continue to experience worsening AD symptoms.
Study identification
- NCT ID
- NCT00384423
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 80 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2006 (Type not available)
- Primary completion
- Oct 2007 (Actual)
- Completion
- Not listed
- Last update posted
- Jan 30, 2008
Started 2006
United States locations
- U.S. sites
- 17
- U.S. states
- 10
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| California Clinical Trials Medical Group, Inc | Paramount | California | 90723 | — |
| Southwest CLinical Research | Rancho Mirage | California | 94109 | — |
| Pacific Research Network, Inc | San Diego | California | 92103 | — |
| San Francisco Clinical Research Center | San Francisco | California | 94109 | — |
| Torrance Clinical Research | Torrance | California | 90505 | — |
| Research Center for Clinical Studies | Darien | Connecticut | 06820 | — |
| Miami Jewish Home and Hospital for the Aged | Miami | Florida | 33137 | — |
| Berma Research | Plantation | Florida | 33317 | — |
| Comprehensive NeuroScience, Inc | St. Petersburg | Florida | 33702 | — |
| Meridien Research | St. Petersburg | Florida | 33709 | — |
| Atlanta Center for Medical Research | Atlanta | Georgia | 30308 | — |
| J. Gary Booker, MD | Shreveport | Louisiana | 71104 | — |
| Neuroscience Research of the Berkshires | Pittsfield | Massachusetts | 01201 | — |
| Neurology Specialists | Dayton | Ohio | 45408 | — |
| Saint Johns Office Building | Tulsa | Oklahoma | 74104 | — |
| The Clinical Trial Center, LLC | Jenkintown | Pennsylvania | 19046 | — |
| Alliance for Neuro Research, LLC | Greenville | South Carolina | 29615 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00384423, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 30, 2008 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00384423 live on ClinicalTrials.gov.