A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin
Public ClinicalTrials.gov record NCT00386100. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Parallel Group, Double-blind, Multi-center Study Comparing the Efficacy and Safety of AVANDAMET and Metformin After 80 Weeks of Treatment.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the longer-term glycemic effect of two medicines approved for initial treatment of type 2 diabetes. The study consists of a 2 week screening period (2 study visits), followed by an 80 week double-blind treatment period (11 study visits). Also, a sub-study was included to look at changes in bone mineral density (BMD) at the lumbar spine.
Study identification
- NCT ID
- NCT00386100
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 688 participants
Conditions and interventions
Conditions
Interventions
- Avandamet 6 mg/1500 mg (ttd) Drug
- Avandamet 4 mg/1000 mg (ttd) Drug
- Avandamet 2 mg/500 mg (ttd) Drug
- Avandamet 8 mg/ 2000 mg (ttd) Drug
- Metformin 500 mg (ttd) Drug
- Metformin 1000 mg (ttd) Drug
- Metformin 1500 mg (ttd) Drug
- Metformin 2000 mg (ttd) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2006 (Type not available)
- Primary completion
- Sep 2009 (Actual)
- Completion
- Sep 2009 (Actual)
- Last update posted
- Nov 23, 2016
2006 – 2009
United States locations
- U.S. sites
- 71
- U.S. states
- 29
- U.S. cities
- 68
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Tuscaloosa | Alabama | 35406 | — |
| GSK Investigational Site | Gilbert | Arizona | 85296 | — |
| GSK Investigational Site | Glendale | Arizona | 85308 | — |
| GSK Investigational Site | Phoenix | Arizona | 85020 | — |
| GSK Investigational Site | Tucson | Arizona | 85712 | — |
| GSK Investigational Site | Tucson | Arizona | 85745 | — |
| GSK Investigational Site | Alhambra | California | 91801 | — |
| GSK Investigational Site | Artesia | California | 90701 | — |
| GSK Investigational Site | Greenbrae | California | 94904 | — |
| GSK Investigational Site | Roseville | California | 95661 | — |
| GSK Investigational Site | Sacramento | California | 95825 | — |
| GSK Investigational Site | Wheat Ridge | Colorado | 80033 | — |
| GSK Investigational Site | Hialeah | Florida | 33013 | — |
| GSK Investigational Site | Ocala | Florida | 34471 | — |
| GSK Investigational Site | Kahului | Hawaii | 96732 | — |
| GSK Investigational Site | Peoria | Illinois | 61615 | — |
| GSK Investigational Site | Avon | Indiana | 46123 | — |
| GSK Investigational Site | Evansville | Indiana | 47710 | — |
| GSK Investigational Site | Evansville | Indiana | 47712 | — |
| GSK Investigational Site | Indianapolis | Indiana | 46254 | — |
| GSK Investigational Site | Waterloo | Iowa | 50702 | — |
| GSK Investigational Site | Slidell | Louisiana | 70461 | — |
| GSK Investigational Site | Sunset | Louisiana | 70584 | — |
| GSK Investigational Site | Elkridge | Maryland | 21075 | — |
| GSK Investigational Site | Chaska | Minnesota | 55318 | — |
| GSK Investigational Site | Minneapolis | Minnesota | 55407-3799 | — |
| GSK Investigational Site | City of Saint Peters | Missouri | 63376 | — |
| GSK Investigational Site | Excelsior Springs | Missouri | 64024 | — |
| GSK Investigational Site | St Louis | Missouri | 63110 | — |
| GSK Investigational Site | St Louis | Missouri | 63128 | — |
| GSK Investigational Site | Billings | Montana | 59102 | — |
| GSK Investigational Site | Las Vegas | Nevada | 89016 | — |
| GSK Investigational Site | Pahrump | Nevada | 89048 | — |
| GSK Investigational Site | Hamilton | New Jersey | 08690 | — |
| GSK Investigational Site | Albuquerque | New Mexico | 87102 | — |
| GSK Investigational Site | East Syracuse | New York | 13057 | — |
| GSK Investigational Site | Flushing | New York | 11355 | — |
| GSK Investigational Site | Kingston | New York | 12401 | — |
| GSK Investigational Site | Huntersville | North Carolina | 28078 | — |
| GSK Investigational Site | Canal Fulton | Ohio | 44614 | — |
| GSK Investigational Site | Canton | Ohio | 44718 | — |
| GSK Investigational Site | Cleveland | Ohio | 44195 | — |
| GSK Investigational Site | Columbus | Ohio | 43210 | — |
| GSK Investigational Site | Kettering | Ohio | 45429 | — |
| GSK Investigational Site | Mogadore | Ohio | 44260 | — |
| GSK Investigational Site | Wandsworth | Ohio | 44281 | — |
| GSK Investigational Site | Oregon City | Oregon | 97045 | — |
| GSK Investigational Site | Beaver | Pennsylvania | 15009 | — |
| GSK Investigational Site | Clairton | Pennsylvania | 15205 | — |
| GSK Investigational Site | Coatsville | Pennsylvania | 19320 | — |
| GSK Investigational Site | Erie | Pennsylvania | 16508 | — |
| GSK Investigational Site | Sewickley | Pennsylvania | 15143 | — |
| GSK Investigational Site | West Chester | Pennsylvania | 19382 | — |
| GSK Investigational Site | Clinton | South Carolina | 29325 | — |
| GSK Investigational Site | Columbia | South Carolina | 29201 | — |
| GSK Investigational Site | Pelzer | South Carolina | 29669 | — |
| GSK Investigational Site | Kingsport | Tennessee | 37660 | — |
| GSK Investigational Site | Corpus Christi | Texas | 78404 | — |
| GSK Investigational Site | Dallas | Texas | 75235 | — |
| GSK Investigational Site | Georgetown | Texas | 78626 | — |
| GSK Investigational Site | South Burlington | Vermont | 05403 | — |
| GSK Investigational Site | Burke | Virginia | 22015 | — |
| GSK Investigational Site | Manassas | Virginia | 20110 | — |
| GSK Investigational Site | Salem | Virginia | 24153 | — |
| GSK Investigational Site | Gig Harbor | Washington | 98335 | — |
| GSK Investigational Site | Graham | Washington | 98338 | — |
| GSK Investigational Site | Olympia | Washington | 98506 | — |
| GSK Investigational Site | Tacoma | Washington | 98405 | — |
| GSK Investigational Site | Vancouver | Washington | 98664 | — |
| GSK Investigational Site | Wenatchee | Washington | 98801 | — |
| GSK Investigational Site | Wauwatosa | Wisconsin | 53228 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00386100, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 23, 2016 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00386100 live on ClinicalTrials.gov.