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Completed Phase 2 Interventional

A Study of Aleglitazar in Patients With Type 2 Diabetes

ClinicalTrials.gov ID: NCT00388518

Public ClinicalTrials.gov record NCT00388518. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 12:59 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind Study to Investigate the Effect of Aleglitazar on Glycemic Control in Patients With Type 2 Diabetes Mellitus.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This 6 arm study will assess the efficacy, safety, tolerability and pharmacokinetics of aleglitazar therapy in patients with Type 2 diabetes. Patients will be randomised to one of 6 treatment arms, to receive one of 4 doses of aleglitazar, Actos as an open-label active comparator, or placebo. Aleglitazar will be administered starting from a dose of 0.05mg po daily, and Actos will be administered at a dose of 45mg once daily. The anticipated time on study treatment is 3-12 months, and the target sample size is 100-500 individuals.

Study identification

NCT ID
NCT00388518
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
332 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2006
Primary completion
Feb 29, 2008
Completion
Feb 29, 2008
Last update posted
Nov 1, 2016

2006 – 2008

United States locations

U.S. sites
18
U.S. states
13
U.S. cities
17
Facility City State ZIP Site status
Not listed Phoenix Arizona 85006
Not listed Phoenix Arizona 85029
Not listed Beverly Hills California 90211
Not listed Palm Springs California 92262
Not listed San Diego California 92161
Not listed Chiefland Florida 32626
Not listed Hollywood Florida 33023
Not listed West Palm Beach Florida 33401
Not listed Augusta Georgia 30909
Not listed Idaho Falls Idaho 83404
Not listed Chicago Illinois 60611
Not listed Baton Rouge Louisiana 70809
Not listed Baltimore Maryland 21229
Not listed Olive Branch Mississippi 38654
Not listed Hamilton New Jersey 08610
Not listed New Hyde Park New York 11042
Not listed Johnson City Tennessee 37604
Not listed Spokane Washington 99216

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 37 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00388518, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 1, 2016 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00388518 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →