Oseltamivir Treatment for Children Less Than 24 Months of Age With Influenza
Public ClinicalTrials.gov record NCT00391768. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Pharmacokinetic/Pharmacodynamic and Safety Evaluation of Oseltamivir (Tamiflu®) for the Treatment of Children Less Than 24 Months of Age With Confirmed Influenza Infection (CASG 114)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to learn how to treat influenza in children less than 2 years of age. Tamiflu®, the drug being studied, is approved for treatment of children 1 year of age and older with influenza. Researchers want to learn more about the activity of Tamiflu® in the body to determine a dose of that is safe, well-tolerated, and effective in young children with influenza. Children less than 24 months of age with confirmed influenza will receive Tamiflu® 2 times a day for 5 days. Older participants will be enrolled first and younger children will be enrolled after the safety data is reviewed for older participants. Study procedures include blood samples, swabs from inside the nose, and body and nervous system evaluations. Participants may be involved in study related procedures for up to 37 days.
Study identification
- NCT ID
- NCT00391768
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 87 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Up to 23 Months
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2007 (Type not available)
- Primary completion
- Mar 2010 (Actual)
- Completion
- Apr 2010 (Actual)
- Last update posted
- May 1, 2013
2007 – 2010
United States locations
- U.S. sites
- 29
- U.S. states
- 19
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35117 | — |
| Arkansas Children's Hospital - Infectious Diseases | Little Rock | Arkansas | 72202-3500 | — |
| Miller Children's Hospital Long Beach - Bickerstaff Family Center | Long Beach | California | 90806-1701 | — |
| Children's Hospital of Orange County | Orange | California | 92868-3835 | — |
| Rady Children's Hospital San Diego | San Diego | California | 92123-4223 | — |
| Children's Hospital Colorado - Infectious Disease | Aurora | Colorado | 80045-7106 | — |
| Children's National Medical Center - Sheikh Zayed Campus - Infectious Disease | Washington D.C. | District of Columbia | 20010-2916 | — |
| University of Florida - Shands Children's Hospital | Gainesville | Florida | 32610-0296 | — |
| University of South Florida - Tampa General Hospital - Pediatrics | Tampa | Florida | 33606-3438 | — |
| Emory Children's Center - Pediatric Infectious Diseases | Atlanta | Georgia | 30322-1014 | — |
| Emory University School of Medicine - Emory Children's Center - Pediatric Infectious Diseases | Atlanta | Georgia | 30322 | — |
| Louisiana State University Health Shreveport - Pediatrics | Shreveport | Louisiana | 71103-4228 | — |
| University of Mississippi - Children's Infectious Diseases | Jackson | Mississippi | 39216-4505 | — |
| Washington University School of Medicine in St. Louis - Center for Clinical Studies | St Louis | Missouri | 63110-1010 | — |
| University of Nebraska Medical Center - Children's Hospital and Medical Center - Infectious Diseases | Omaha | Nebraska | 68114-4108 | — |
| Cohen Children's Medical Center - Pediatric Infectious Diseases | Manhasset | New York | 11030-3816 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| SUNY Upstate Medical University Hospital - Pediatrics | Syracuse | New York | 13210-2342 | — |
| Cincinnati Children's Hospital Medical Center - Infectious Diseases | Cincinnati | Ohio | 45229-3026 | — |
| MetroHealth Medical Center - Pediatric Infectious Disease | Cleveland | Ohio | 44109-1998 | — |
| Children's Hospital of Philadelphia - The Center for Pediatric Clinical Effectiveness | Philadelphia | Pennsylvania | 19104-3309 | — |
| Children's Hospital of Pittsburgh of UPMC - General Academic Pediatric | Pittsburgh | Pennsylvania | 15213-3205 | — |
| Rhode Island Hospital - Pediatrics | Providence | Rhode Island | 02903-4923 | — |
| Vanderbilt University - Pediatric - Infectious Diseases | Nashville | Tennessee | 37232-0011 | — |
| Parkland Memorial Hospital | Dallas | Texas | 75235-7708 | — |
| The University of Texas Southwestern Medical Center | Dallas | Texas | 75390-9063 | — |
| Cook Children's Infectious Disease Services | Fort Worth | Texas | 76104-2710 | — |
| University of Utah - Pediatric Pharmacology Program | Salt Lake City | Utah | 84108-1457 | — |
| Seattle Children's Hospital - Infectious Diseases | Seattle | Washington | 98105-3901 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00391768, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 1, 2013 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00391768 live on ClinicalTrials.gov.