Placebo-Controlled Study of Perifosine + Single Agent Chemotherapy for Metastatic Cancer Patients
Public ClinicalTrials.gov record NCT00398879. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Placebo-Controlled Study of Perifosine in Combination With Single Agent Chemotherapy for Metastatic Cancer Patients
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is an exploratory phase 2, randomized placebo-controlled trial with stratification for disease and chemotherapy type. The study is subsequently closed to enrollment in all arms except patients with metastatic colorectal cancer which would be randomized to either capecitabine plus perifosine or capecitabine alone. The effects of perifosine may be manifested by increased time to progression, tumor regression reflected in partial or complete responses, or a combination of these outcomes. The primary goal of this trial is to obtain a preliminary and objective assessment of the effects of perifosine on time to progression.
Study identification
- NCT ID
- NCT00398879
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 381 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2005 (Type not available)
- Primary completion
- Dec 2010 (Actual)
- Completion
- Oct 2011 (Actual)
- Last update posted
- Mar 14, 2018
2005 – 2011
United States locations
- U.S. sites
- 49
- U.S. states
- 22
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AOI Pharmaceuticals Investigative Site | Tucson | Arizona | 85704 | — |
| AOI Pharmaceuticals Investigative Site | Beverly Hills | California | 90211 | — |
| AOI Pharmaceuticals Investigative Site | Deer Park | California | 94574 | — |
| AOI Pharmaceuticals Investigative Site | Monterey | California | 93940 | — |
| AOI Pharmaceuticals Investigative Site | Newport Beach | California | 92663 | — |
| AOI Pharmaceuticals Investigative Site | Pomona | California | 91767 | — |
| AOI Pharmaceuticals Investigative Site | Santa Rosa | California | 95403 | — |
| AOI Pharmaceuticals Investigative Site | Soquel | California | 95703 | — |
| AOI Pharmaceuticals Investigative Site | Stockton | California | 95207 | — |
| AOI Pharmaceuticals Investigative Site | Colorado Springs | Colorado | 80909 | — |
| AOI Pharmaceuticals Investigative Site | Greeley | Colorado | 80631 | — |
| AOI Pharmaceuticals Investigative Site | Middletown | Connecticut | 06457 | — |
| AOI Pharmaceuticals Investigative Site | Norwich | Connecticut | 06360 | — |
| AOI Pharmaceuticals Investigative Site | Aventura | Florida | 33180 | — |
| AOI Pharmaceuticals Investigative Site | Coral Springs | Florida | 33065 | — |
| AOI Pharmaceuticals Investigative Site | Lake City | Florida | 32055 | — |
| AOI Pharmaceuticals Investigative Site | Miami | Florida | 33176 | — |
| AOI Pharmaceuticals Investigative Site | Ormond Beach | Florida | 32174 | — |
| AOI Pharmaceuticals Investigative Site | Sebastian | Florida | 32958 | — |
| AOI Pharmaceuticals Investigative Site | Vero Beach | Florida | 32960 | — |
| AOI Pharmaceuticals Investigative Site | Augusta | Georgia | 30904 | — |
| AOI Pharmaceuticals Investigative Site | Lawrenceville | Georgia | 30045 | — |
| AOI Pharmaceuticals Investigative Site | Marietta | Georgia | 30060 | — |
| AOI Pharmaceuticals Investigative Site | Galesburg | Illinois | 61401 | — |
| AOI Pharmaceuticals Investigative Site | Park Ridge | Illinois | 60068 | — |
| AOI Pharmaceuticals Investigative Site | Louisville | Kentucky | 40202 | — |
| AOI Pharmaceuticals Investigative Site | Lafayette | Louisiana | 70506 | — |
| AOI Pharmaceuticals Investigative Site | Grand Rapids | Michigan | 49546 | — |
| AOI Pharmaceuticals Investigative Site | Kalamazoo | Michigan | 49048 | — |
| AOI Pharmaceuticals Investigative Site | Branson | Missouri | 65616 | — |
| AOI Pharmaceuticals Investigative Site | Billings | Montana | 59103 | — |
| AOI Pharmaceuticals Investigative Site | Great Falls | Montana | 59405 | — |
| AOI Pharmaceuticals Investigative Site | Albany | New York | 12208 | — |
| AOI Pharmaceuticals Investigative Site | Armonk | New York | 10504 | — |
| AOI Pharmaceuticals Investigative Site | Great Neck | New York | 11042 | — |
| AOI Pharmaceuticals Investigative Site | Wilmington | North Carolina | 28401 | — |
| AOI Pharmaceuticals Investigative Site | Dayton | Ohio | 45409 | — |
| AOI Pharmaceuticals Investigative Site | Pottsville | Pennsylvania | 17901 | — |
| AOI Pharmaceuticals Investigative Site | Sayre | Pennsylvania | 18840 | — |
| AOI Pharmaceuticals Investigative Site | Greenville | South Carolina | 29605 | — |
| AOI Pharmaceuticals Investigative Site | Chattanooga | Tennessee | 37404 | — |
| AOI Pharmaceuticals Investigative Site | Memphis | Tennessee | 38120 | — |
| AOI Pharmaceuticals Investigative Site | Dallas | Texas | 75231 | — |
| AOI Pharmaceuticals Investigative Site | Dallas | Texas | 75246 | — |
| AOI Pharmaceuticals Investigative Site | Tyler | Texas | 75702 | — |
| AOI Pharmaceuticals Investigative Site | Chesapeake | Virginia | 23320 | — |
| AOI Pharmaceuticals Investigative Site | Norfolk | Virginia | 23502 | — |
| AOI Pharmaceuticals Investigative Site | Spokane | Washington | 99218 | — |
| AOI Pharmaceuticals Investigative Site | Appleton | Wisconsin | 54915 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00398879, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 14, 2018 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00398879 live on ClinicalTrials.gov.