Study to Evaluate Safety, Tolerability, and Effect of AL208 on Mild Cognitive Impairment Following Coronary Artery Bypass Graft Surgery
Public ClinicalTrials.gov record NCT00404014. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Study Designed to Evaluate the Safety, Tolerability, and Effect of a Single, Rising Dose of Intravenous AL-208, Followed by a Placebo-Controlled, Double-Blind, Parallel-Group Evaluation of a Single Dose of AL-208, on Mild Cognitive Impairment Following Coronary Artery Bypass Graft Surgery.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective is to compare mild cognitive impairment in the AL-208 group with the placebo group at 14 + - 3 days after CABG surgery
Study identification
- NCT ID
- NCT00404014
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 234 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 79 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2006 (Type not available)
- Primary completion
- Jun 2008 (Actual)
- Completion
- Jun 2008 (Actual)
- Last update posted
- Oct 24, 2012
2006 – 2008
United States locations
- U.S. sites
- 26
- U.S. states
- 16
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Physicians Clinical Research Corp. | Laguna Hills | California | 92653 | — |
| Sacramento Heart and Vascular Research Center | Sacramento | California | 95825 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Miami Research Associates | South Miami | Florida | 33143 | — |
| Piedmont Hospital Research Institute | Atlanta | Georgia | 30309 | — |
| The Atlanta Heart and Vascular Research Group | Atlanta | Georgia | 30342 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Chicago Heart Institute and Vein Clinic | Elk Grove Village | Illinois | 60007 | — |
| Illinois Heart and Vascular Foundation | Hindsdale | Illinois | 60521 | — |
| Indiana/Ohio Heart Cardiothoracic and Vascular Surgeons | Fort Wayne | Indiana | 46804 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| Cardiothoracic Associates | Flint | Michigan | 48532 | — |
| NYU Medical Center | New York | New York | 10016 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Carolina Cardiovascular Surgical Associates, PA | Raleigh | North Carolina | 27610 | — |
| Memory Assessment and Research Services | Wilmington | North Carolina | 28405 | — |
| St. Vincent Mary Medical Center | Toledo | Ohio | 43608 | — |
| Tulsa Clinical Resesarch, LLC | Tulsa | Oklahoma | 74104-5428 | — |
| Consultants in Cardiovascular Diseases Inc. | Erie | Pennsylvania | 16502 | — |
| Clinical Research Solutions, PC | Knoxville | Tennessee | 37920 | — |
| Vanderbilt University | Nashville | Tennessee | 37212 | — |
| Clinical Cardiovascular Research Center | Dallas | Texas | 75226 | — |
| St. Luke's Episcopal Hospital | Houston | Texas | 77030 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| Cardiac and Thoracic Surgical Associates, Ltd. | Mechanicsville | Virginia | 23116 | — |
| Multicare Health Systems | Tacoma | Washington | 98415 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00404014, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 24, 2012 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00404014 live on ClinicalTrials.gov.