Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Active Ulcerative Colitis
Public ClinicalTrials.gov record NCT00408629. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Placebo-controlled Study of the Human Anti-TNF Monoclonal Antibody Adalimumab for the Induction and Maintenance of Clinical Remission in Subjects With Moderately to Severely Active Ulcerative Colitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This was a Phase 3, multicenter, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy and safety of the human anti-tumor necrosis factor (TNF) monoclonal antibody adalimumab (ADA) in patients with moderately to severely active ulcerative colitis (UC).
Study identification
- NCT ID
- NCT00408629
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 518 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2006 (Type not available)
- Primary completion
- Mar 2010 (Actual)
- Completion
- Mar 2010 (Actual)
- Last update posted
- May 3, 2011
2006 – 2010
United States locations
- U.S. sites
- 36
- U.S. states
- 21
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site Ref # / Investigator 5394 | Anaheim | California | 92801 | — |
| Site Ref # / Investigator 3753 | Wheat Ridge | Colorado | 80033 | — |
| Site Ref # / Investigator 3754 | Hamden | Connecticut | 06518 | — |
| Site Ref # / Investigator 12903 | Gainesville | Florida | 32607 | — |
| Site Ref # / Investigator 3747 | Hollywood | Florida | 33021 | — |
| Site Ref # / Investigator 5106 | Jacksonville | Florida | 32256 | — |
| Site Ref # / Investigator 11601 | Naples | Florida | 34102 | — |
| Site Ref # / Investigator 6846 | Sarasota | Florida | 34239 | — |
| Site Ref # / Investigator 3742 | Winter Park | Florida | 32789 | — |
| Site Ref # / Investigator 3760 | Zephyrhills | Florida | 33542 | — |
| Site Ref # / Investigator 3739 | Atlanta | Georgia | 30342 | — |
| Site Ref # / Investigator 7658 | Macon | Georgia | 31201 | — |
| Site Ref # / Investigator 5397 | Moline | Illinois | 61265 | — |
| Site Ref # / Investigator 7453 | Topeka | Kansas | 66606 | — |
| Site Ref # / Investigator 3759 | Annapolis | Maryland | 21401 | — |
| Site Ref # / Investigator 3762 | Annapolis | Maryland | 21401 | — |
| Site Ref # / Investigator 3738 | Lutherville | Maryland | 21093 | — |
| Site Ref # / Investigator 7472 | Troy | Michigan | 48098 | — |
| Site Ref # / Investigator 3744 | Rochester | Minnesota | 55905 | — |
| Site Ref # / Investigator 6088 | St Louis | Missouri | 63128 | — |
| Site Ref # / Investigator 3756 | Great Neck | New York | 11021 | — |
| Site Ref # / Investigator 3752 | Charlotte | North Carolina | 28207 | — |
| Site Ref # / Investigator 3758 | Jacksonville | North Carolina | 28546 | — |
| Site Ref # / Investigator 3745 | Cincinnati | Ohio | 45219 | — |
| Site Ref # / Investigator 7709 | Oklahoma City | Oklahoma | 73104 | — |
| Site Ref # / Investigator 3740 | Tulsa | Oklahoma | 74104 | — |
| Site Ref # / Investigator 3765 | Sayre | Pennsylvania | 18840 | — |
| Site Ref # / Investigator 3741 | Columbia | South Carolina | 29204 | — |
| Site Ref # / Investigator 3737 | Germantown | Tennessee | 38138 | — |
| Site Ref # / Investigator 6077 | Nashville | Tennessee | 37203 | — |
| Site Ref # / Investigator 5107 | Nashville | Tennessee | 37205 | — |
| Site Ref # / Investigator 3743 | Nashville | Tennessee | 37212-1610 | — |
| Site Ref # / Investigator 5398 | Ogden | Utah | 84405 | — |
| Site Ref # / Investigator 8064 | Spokane | Washington | 99202 | — |
| Site Ref # / Investigator 3750 | Spokane | Washington | 99204 | — |
| Site Ref # / Investigator 3761 | West Bend | Wisconsin | 53095 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 72 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00408629, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 3, 2011 · Synced Oct 30, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00408629 live on ClinicalTrials.gov.