Cancer Vaccine Study for Unresectable Stage III Non-small Cell Lung Cancer (START)
Public ClinicalTrials.gov record NCT00409188. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-center Phase III Randomized, Double-blind Placebo-controlled Study of the Cancer Vaccine Stimuvax® (L-BLP25 or BLP25 Liposome Vaccine) in Non-small Cell Lung Cancer (NSCLC) Subjects With Unresectable Stage III Disease.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether the cancer vaccine tecemotide (L-BLP25) in addition to best supportive care is effective in prolonging the lives of subjects with unresectable stage III non-small cell lung cancer, compared to best supportive care alone. A local ancillary (sub) study in European centers will evaluate the immune response in peripheral blood after tecemotide (L-BLP25) or placebo vaccination.
Study identification
- NCT ID
- NCT00409188
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,513 participants
Conditions and interventions
Conditions
Interventions
- Tecemotide (L-BLP25) Biological
- Single low dose cyclophosphamide Drug
- Placebo Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2007 (Type not available)
- Primary completion
- Apr 2012 (Actual)
- Completion
- Apr 2015 (Actual)
- Last update posted
- Nov 20, 2015
2007 – 2015
United States locations
- U.S. sites
- 49
- U.S. states
- 24
- U.S. cities
- 44
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Saint Edward Mercy Medical Center | Fort Smith | Arkansas | 72901 | — |
| Pacific Cancer Medical Center | Anaheim | California | 92801 | — |
| Glendale Adventist Medical Center | Glendale | California | 91206 | — |
| Norris Cancer Hospital | Los Angeles | California | 90033 | — |
| Cedars-Sinai Outpatient Cancer Center at the Samuel Oschin Comprehensive Cancer Institute | Los Angeles | California | 90048 | — |
| Clinical Trials and Research Associates, Inc. | Montebello | California | 90640 | — |
| Desert Hematology Oncology Medical Group, Inc | Rancho Mirage | California | — | — |
| Stockton Hematology Oncology Medical Group, Inc. | Stockton | California | 95204 | — |
| University of Colorado Cancer Center | Denver | Colorado | 80045 | — |
| Pasco Hernando Oncology Associates P.A | Brooksville | Florida | 34613 | — |
| University of Miami, Sylvester Comprehensive Cancer Center | Miami | Florida | — | — |
| Pasco Hernando Oncology Associates, PA | New Port Richey | Florida | 34652 | — |
| Florida Hospital Memorial System | Ormond Beach | Florida | 32174 | — |
| Southern Illinois Hematology/Oncology | Centralia | Illinois | 62801 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Joliet Oncology-Hematology Associates, Ltd. | Joliet | Illinois | 60435 | — |
| Kentucky Cancer Center | Hazard | Kentucky | 41701 | — |
| Leonard J. Chabert Medical Center | Houma | Louisiana | — | — |
| Hematology and Oncology Specialists, LLC | Metarie | Louisiana | 70006 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| University of Maryland, Marlene and Steward Greenbaum Cancer Center | Baltimore | Maryland | — | — |
| Lahey Clinic | Burlington | Massachusetts | — | — |
| Oncology Care Associates | Saint Joseph | Michigan | 49085 | — |
| University of Minnesota Physicians, Masonic Cancer Center | Minneapolis | Minnesota | — | — |
| Saint Louis University Cance Center | St Louis | Missouri | — | — |
| Deaconess Billings Clinic | Billings | Montana | 59101 | — |
| Big Sky Oncology, Sletten Cancer Institute | Great Falls | Montana | 59405 | — |
| Nebraska Cancer Care, LLC | Hastings | Nebraska | 68901 | — |
| Southeast Nebraska Cancer Center | Lincoln | Nebraska | 68510 | — |
| St. Vincents Comprehensive Cancer Center | New York | New York | 10011 | — |
| Hematology Oncology Associates of Rockland | Nyack | New York | 10960 | — |
| Univ. of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | — |
| Carolinas Hematology-Oncology | Charlotte | North Carolina | 28203 | — |
| Hanover Medical Specialts PA | Wilmington | North Carolina | 28401 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Signal Point Clinical Research Center, LLC | Middletown | Ohio | 45042 | — |
| Southwestern Regional Medical Center | Tulsa | Oklahoma | 74133 | — |
| Southwestern Regional Medical Center | Tulsa | Oklahoma | — | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Univ. of Pennsylvania Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| The Jones Clinic, PC | Germantown | Tennessee | 38138 | — |
| Center for Oncology Research | Dallas | Texas | 75230 | — |
| John Peter Smith Center for Cancer Care | Fort Worth | Texas | 76104 | — |
| The Center for Cancer and Blood Disorders | Fort Worth | Texas | 76104 | — |
| Cancer Therapy & Research Center, Institute for Drug Development | San Antonio | Texas | 78229 | — |
| Fairfax-Northern Virginia Hematology Oncology, PC | Fairfax | Virginia | 22031 | — |
| Wheeling Hospital | Wheeling | West Virginia | 26003 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 241 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00409188, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 20, 2015 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00409188 live on ClinicalTrials.gov.