SMP-986 Phase 2 Proof of Concept in Patients With Overactive Bladder Syndrome (OABS)
Public ClinicalTrials.gov record NCT00409539. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 10-week Randomised, DB, PG, PC Phase 2 Study to Investigate the Extent of Symptom Relief and the Safety and Tolerability of SMP-986 (20, 40, 80 and 120 mg) Administered Once Daily for 8 Weeks to Patients With Overactive Bladder Syndrome
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
SMP-986 is a compound being developed for the treatment of overactive bladder syndrome (OABS). This clinical study is designed to test the hypothesis that SMP-986 at doses of 20mg, 40mg, 80mg or 120mg provides greater symptom relief in OABS compared to placebo. The hypothesis will be tested by measuring the change in mean voids/24 hrs after treatment with SMP-986 compared to placebo, as well comparing the change in: the severity of urgency episodes, mean number of urgency episodes/24 hr, mean number of incontinence episodes/24 hr and the mean void volume/void between SMP-986 and placebo.
Study identification
- NCT ID
- NCT00409539
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 550 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 20 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2006
- Primary completion
- May 31, 2008
- Completion
- Jun 30, 2008
- Last update posted
- Dec 9, 2014
2006 – 2008
United States locations
- U.S. sites
- 21
- U.S. states
- 13
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Visions Clinical Research | Tuscon | Arizona | 85712 | — |
| Peninsula Urology Center | Atherton | California | 94027 | — |
| San Bernadino Urological Association Medical Group | San Bernadino | California | 92404 | — |
| 9040 Friars Road | San Diego | California | 92108 | — |
| South Florida Medical Research | Aventura | Florida | 33180 | — |
| Visions Clinical Research | Boynton Beach | Florida | 33437 | — |
| Florida Healthcare Research | Ocala | Florida | 34474 | — |
| Southern Research Group, Centre Point Boulevard | Tallahassee | Florida | 32308 | — |
| Atlanta Medical Research | Alpharetta | Georgia | 30005 | — |
| Urological Surgeons of IL | Kankakee | Illinois | 60901 | — |
| Regional Urology | Shreveport | Louisiana | 71106 | — |
| Accumed Research Associate | Garden City | New York | 11530 | — |
| Hudson Valley Urology | Kingston | New York | 12401 | — |
| New York Urological Associates, PC | New York | New York | 10022 | — |
| Hudson Valley Urology | Poughkeepsie | New York | 12601 | — |
| Unifour Medical Research | Hickory | North Carolina | 28601 | — |
| University of Pittsburg, Dept Urology | Pittsburgh | Pennsylvania | 15213 | — |
| Volunteer Research Group | Knoxville | Tennessee | 37920 | — |
| 5920 Saratoga Boulevard | Corpus Christi | Texas | 78414 | — |
| National Clinical Research Inc | Richmond | Virginia | 23294 | — |
| 801 W. 5th Avenue | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 48 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00409539, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 9, 2014 · Synced Sep 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00409539 live on ClinicalTrials.gov.