Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)
Public ClinicalTrials.gov record NCT00412360. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
Multi-center, Open Label, Randomized Trial Comparing Single Versus Double Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia (BMT CTN #0501)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a Phase III, randomized, open-label, multi-center, prospective study of single umbilical cord blood (UCB) transplantation versus double UCB transplantation in pediatric patients with hematologic malignancies.
Study identification
- NCT ID
- NCT00412360
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 224 participants
Conditions and interventions
Conditions
Interventions
- Single Umbilical Cord Blood Unit Transplant Biological
- Double Umbilical Cord Blood Unit Transplant Biological
- Total Body Irradiation Radiation
- Cyclophosphamide Drug
- Fludarabine Drug
- Cyclosporine A Drug
- Mycophenolate Mofetil Drug
Biological · Radiation · Drug
Eligibility (public fields only)
- Age range
- 1 Year to 21 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2006 (Type not available)
- Primary completion
- Mar 2014 (Actual)
- Completion
- Oct 2014 (Actual)
- Last update posted
- Oct 28, 2021
2006 – 2014
United States locations
- U.S. sites
- 36
- U.S. states
- 27
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35294 | — |
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| City of Hope National Medical Center | Duarte | California | 91010 | — |
| Childrens Hospital at Oakland | Oakland | California | 94609 | — |
| UCSD/Rady Childrens Hospital | San Diego | California | 92123 | — |
| University of California, San Francisco (Peds) | San Francisco | California | 94143 | — |
| The Children's Hospital of Denver | Denver | Colorado | 80218 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| University of Florida College of Medicine (Shands) | Gainesville | Florida | 32610 | — |
| Nemours Childrens Clinic | Jacksonville | Florida | 32207 | — |
| University of Miami | Miami | Florida | 33136 | — |
| All Children's Hospital | St. Petersburg | Florida | 33710 | — |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30322-1062 | — |
| Indiana University Medical Center | Indianapolis | Indiana | 46202 | — |
| University of Louisville/Kosiar Children's Hospital | Louisville | Kentucky | 40202 | — |
| Children's of New Orleans | New Orleans | Louisiana | 70118 | — |
| DFCI/Children's Hospital of Boston | Boston | Massachusetts | 02115 | — |
| University of Michigan Medical Center | Ann Arbor | Michigan | 48109 | — |
| Karmanos Cancer Institute/Children's Hospital of Michigan | Detroit | Michigan | 48201 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| University of Mississippi | Jackson | Mississippi | 39216 | — |
| Children's Mercy Hospital and Clinics | Kansas City | Missouri | 64108 | — |
| New York Medical College | Valhalla | New York | 10595 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Nationwide Children's Hospital | Columbus | Ohio | 43205-2696 | — |
| Oregon Health Sciences University | Portland | Oregon | 97239 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232-7610 | — |
| Children's Medical Center of Dallas | Dallas | Texas | 75235 | — |
| Cook Childrens Medical Center | Fort Worth | Texas | 76104 | — |
| Texas Transplant Institute | San Antonio | Texas | 78229 | — |
| Utah BMT/University of Utah Medical School | Salt Lake City | Utah | 84132 | — |
| Virgina Commonwealth University | Richmond | Virginia | 23298 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53211 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00412360, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 28, 2021 · Synced Nov 9, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00412360 live on ClinicalTrials.gov.