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Terminated Phase 2 Interventional

A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) Pain

ClinicalTrials.gov ID: NCT00418782

Public ClinicalTrials.gov record NCT00418782. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 26, 2026, 2:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A 2 Week, Randomized, Double Blind, Placebo And Positive Controlled, Parallel Group, Multicenter Study Of CE-224,535 In Subjects With Osteoarthritic Pain Of The Knee

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

CE-224535 is a new medication being developed as an analgesic and anti-inflammatory agent for the treatment of the signs and symptoms of osteoarthritis (OA). The purpose of this study is to evaluate the analgesic and anti inflammatory efficacy and safety of CE 224,535 versus placebo and naproxen treatment in patients with OA knee pain.

Study identification

NCT ID
NCT00418782
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
212 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2006
Primary completion
Not listed
Completion
Jul 31, 2007
Last update posted
Dec 4, 2018

2007

United States locations

U.S. sites
46
U.S. states
21
U.S. cities
42
Facility City State ZIP Site status
Pfizer Investigational Site Anniston Alabama 36207 —
Pfizer Investigational Site Bayou La Batre Alabama 36509 —
Pfizer Investigational Site Birmingham Alabama 35209 —
Pfizer Investigational Site Birmingham Alabama 35216 —
Pfizer Investigational Site Birmingham Alabama 35242 —
Pfizer Investigational Site Hot Springs Arkansas 71913 —
Pfizer Investigational Site Northridge California 91325 —
Pfizer Investigational Site Sacramento California 95825 —
Pfizer Investigational Site Tarzana California 91356 —
Pfizer Investigational Site Denver Colorado 80204 —
Pfizer Investigational Site Denver Colorado 80206 —
Pfizer Investigational Site Westminster Colorado 80030 —
Pfizer Investigational Site Clearwater Florida 33761 —
Pfizer Investigational Site DeFuniak Springs Florida 32435 —
Pfizer Investigational Site Destin Florida 32541 —
Pfizer Investigational Site Pensacola Florida 32503 —
Pfizer Investigational Site Chicago Illinois 60053 —
Pfizer Investigational Site Gurnee Illinois 60031 —
Pfizer Investigational Site Avon Indiana 46123 —
Pfizer Investigational Site Indianapolis Indiana 46250 —
Pfizer Investigational Site Gretna Louisiana 70056 —
Pfizer Investigational Site Kenner Louisiana 70065 —
Pfizer Investigational Site Metairie Louisiana 70002 —
Pfizer Investigational Site Baltimore Maryland 21218 —
Pfizer Investigational Site Frederick Maryland 21702 —
Pfizer Investigational Site Flowood Mississippi 39232 —
Pfizer Investigational Site Columbia Missouri 65212 —
Pfizer Investigational Site Kansas City Missouri 64114 —
Pfizer Investigational Site Missoula Montana 59802 —
Pfizer Investigational Site Trenton New Jersey 08611 —
Pfizer Investigational Site Beavercreek Ohio 45440 —
Pfizer Investigational Site Cincinnati Ohio 45242 —
Pfizer Investigational Site Kettering Ohio 45429 —
Pfizer Investigational Site Ashland Oregon 97520 —
Pfizer Investigational Site Eugene Oregon 97404 —
Pfizer Investigational Site Duncansville Pennsylvania 16635 —
Pfizer Investigational Site Summerville South Carolina 29485 —
Pfizer Investigational Site Collierville Tennessee 38017 —
Pfizer Investigational Site Knoxville Tennessee 37909-1900 —
Pfizer Investigational Site Memphis Tennessee 38104 —
Pfizer Investigational Site Bryan Texas 77802 —
Pfizer Investigational Site Longview Texas 75605 —
Pfizer Investigational Site San Antonio Texas 78213 —
Pfizer Investigational Site San Antonio Texas 78229 —
Pfizer Investigational Site Arlington Virginia 22205 —
Pfizer Investigational Site Spokane Washington 99216 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00418782, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 4, 2018 · Synced Sep 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00418782 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →