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Completed Phase 3 Interventional

Effectiveness and Safety Trial of a New Ischemic Stroke Treatment Within 24 Hours From Stroke Onset (NEST-2)

ClinicalTrials.gov ID: NCT00419705

Public ClinicalTrials.gov record NCT00419705. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:58 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

NeuroThera® Effectiveness and Safety Trial - 2 (NEST-2) A Double Blind, Randomized, Controlled, Parallel Group, Multicenter, Pivotal Study to Assess the Safety and Effectiveness of the Treatment of Acute Ischemic Stroke With the NeuroThera® Laser System Within 24 Hours From Stroke Onset

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this pivotal study is to demonstrate safety and effectiveness of the NeuroThera® Laser System (referred to hereafter as NTS) in the treatment of Subjects diagnosed with acute ischemic stroke. The initiation of NTS treatment must be feasible for each Subject within 24 hours of stroke onset.

Study identification

NCT ID
NCT00419705
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
PhotoThera, Inc
Industry
Enrollment
660 participants

Conditions and interventions

Interventions

Device

Eligibility (public fields only)

Age range
40 Years to 90 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2006
Primary completion
Jun 30, 2008
Completion
Jun 30, 2008
Last update posted
Jun 8, 2011

2006 – 2008

United States locations

U.S. sites
51
U.S. states
25
U.S. cities
48
Facility City State ZIP Site status
Sparks Regional Medical Center Fort Smith Arkansas 72901
Alta Bates Summit Medical Center Berkeley California 94705
Scripps Encinitas Hospital Encinitas California 92024
Grossmont Hospital La Mesa California 91942
UCLA Medical Center Los Angeles California 90095
Tri City Medical Center Oceanside California 92056
Stanford Hospital and Clinics Palo Alto California 94305
Sharp Healthcare San Diego California 92123
Neurology Medical Group of Diablo Valley Walnut Creek California 94598
Swedish Medical Center Englewood Colorado 80113
The Stroke Center at Hartford Hospital Hartford Connecticut 06102
North Broward Medical Center Deerfield Beach Florida 33064
Holy Cross Hospital Fort Lauderdale Florida 33308
Health First Holmes Regional Medical Center Melbourne Florida 32901
Naples Community Hospital Naples Florida 34101
Munroe Regional Medical Center Ocala Florida 34474
Fawcett Memorial Hospital Port Charlotte Florida 33952
Dekalb Medical Center Decatur Georgia 30033
Dekalb Neurology Associates LLC Decatur Georgia 30033
The Queen's Medical Center Honolulu Hawaii 92822
Intensive Care Unit, Northwestern Memorial Hospital Chicago Illinois 60611
Loyola University Chicago Maywood Illinois 60153
Parkview Hospital Fort Wayne Indiana 46805
University of Kentucky Chandler Medical Center Lexington Kentucky 40536
Beth Israel Deaconess Medical Center Boston Massachusetts 02215
University Massachusetts Memorial Medical Center Worcester Massachusetts 01655
North Memorial Medical Center Robbinsdale Minnesota 55422
St. Luke's Hospital Kansas City Missouri 64111
Saint Louis University St Louis Missouri 63110
Benefis Healthcare East Campus Great Falls Montana 59405
Virtua Memorial Hospital of Burlington County Mount Holly New Jersey 08060
The Valley Hospital Ridgewood New Jersey 07450
Mission Hospitals - Memorial Campus Asheville North Carolina 28801
UNC Health Care Chapel Hill North Carolina 27514
Duke University Medical Center Durham North Carolina 27710
The Moses H. Cone Memorial Hospital Greensboro North Carolina 27401
Forsyth Medical Center Winston-Salem North Carolina 27103
The University Hospital Cincinnati Ohio 45219
The Cleveland Clinic Foundation Cleveland Ohio 44195
Providence Portland Hospital Portland Oregon 97213
Oregon Health & Science University - Oregon Stroke Center Portland Oregon 97239
Thomas Jefferson University Hospital Philadelphia Pennsylvania 19107
Hospital of University of Pennsylvania Philadelphia Pennsylvania 19140
Roper Hospital Charleston South Carolina 29401
Erlanger Health System Chattanooga Tennessee 37403
The Methodist Hospital Houston Texas 77030
Virginia Commonwealth University Medical Center Richmond Virginia 23298
Sentara Virginia Beach General Hospital Virginia Beach Virginia 23454
Winchester Medical Center Winchester Virginia 22601
Charleston Area Medical Center (CAMC) General Hospital Charleston West Virginia 25301
University of Wisconsin Hospital and Clinics Madison Wisconsin 53795

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00419705, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 8, 2011 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00419705 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →