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Completed Phase 2 Interventional Results available

A Dose Finding Study Of PF-00489791 In Patients With Mild To Moderate High Blood Pressure

ClinicalTrials.gov ID: NCT00422461

Public ClinicalTrials.gov record NCT00422461. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 7:45 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 2, RANDOMIZED, PLACEBO-CONTROLLED, DOSE-RANGING STUDY OF PF-00489791 IN SUBJECTS WITH STAGE 1 AND 2 ESSENTIAL HYPERTENSION USING AMBULATORY BLOOD PRESSURE MONITORING (ABPM)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety and blood pressure lowering effect of different doses of PF-00489791 in patients with mild to moderate high blood pressure

Study identification

NCT ID
NCT00422461
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pfizer
Industry
Enrollment
135 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 26, 2007
Primary completion
Jan 27, 2008
Completion
Jan 27, 2008
Last update posted
Oct 10, 2021

2007 – 2008

United States locations

U.S. sites
20
U.S. states
10
U.S. cities
18
Facility City State ZIP Site status
National Research Institute Los Angeles California 90057
Apex Research Institute Santa Ana California 92705
Orange County Research Center Tustin California 92780
University of Connecticut Health Center Farmington Connecticut 06030-3940
Chase Medical Research, LLC Waterbury Connecticut 06708
Jacksonville Center for Clinical Research Jacksonville Florida 32216
Andres Patron, DO, PA Pembroke Pines Florida 33026
Commonwealth Biomedical Research, LLC Madisonville Kentucky 42431
Twin Cities Clinical Research Brooklyn Center Minnesota 55430
Riser Medical Associates Picayune Mississippi 39466
Midwest Internists Clinical Research, P.C. St Louis Missouri 63141
Triangle Medical Research Associates, LLC Cary North Carolina 27518
Medical Research Associates of Charlotte, Inc Charlotte North Carolina 28277
Triangle Medical Research Associates Raleigh North Carolina 27609
Triangle Medical Research Raleigh North Carolina 27609
Piedmont Medical Research Associates Winston-Salem North Carolina 27103
Sterling Research Group limited Cincinnati Ohio 45246
New Orleans Center for Clinical Research Knoxville Tennessee 37920
Volunteer Research Group Knoxville Tennessee 37920
Clinical Research Associates Incorporated Nashville Tennessee 37203

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00422461, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 10, 2021 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00422461 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →