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Terminated Phase 2 Interventional Results available

A Study of E2007 In Patients With Parkinson's Disease

ClinicalTrials.gov ID: NCT00427011

Public ClinicalTrials.gov record NCT00427011. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 2:24 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of E2007 In Patients With Parkinson's Disease Who Experience End-of-Dose "Wearing-Off" Motor Fluctuations

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Phase IIb open-label extension study for patients with Parkinson's Disease. All patients will receive active study drug. The study will involve outpatient visits only. Patients who completed Study E2007-A001-214 (Cohorts I and II) and who meet inclusion/exclusion criteria will be enrolled and enter the 12-week Titration Phase (from "Dispense Study Drug" at Week 0 \[Visit 2\] through Week 12 \[Visit 7\]) followed by the Maintenance Phase (from Week 12 \[Visit 7\] to end of study).

Study identification

NCT ID
NCT00427011
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eisai Inc.
Industry
Enrollment
25 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2007
Primary completion
Mar 31, 2008
Completion
Mar 31, 2008
Last update posted
Feb 10, 2013

2007 – 2008

United States locations

U.S. sites
9
U.S. states
6
U.S. cities
9
Facility City State ZIP Site status
Pivotal Research Centers Peoria Arizona 85381
Clinical Trials Incorporated Little Rock Arkansas 72205
Pacific Neuroscience Medical Group Oxnard California 93030
Parkinson's Disease and Movement Disorders Center of Boca Raton Boca Raton Florida 33486
Brain Matters Research Delray Beach Florida 33445
Charlotte Neurological Services Port Charlotte Florida 33952
Suncoast Neuroscience Associates, Inc. St. Petersburg Florida 33701
Raleigh Neurology Associates Raleigh North Carolina 27607
Agape Medical Research Center, Inc. Lubbock Texas 79410

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00427011, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 10, 2013 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00427011 live on ClinicalTrials.gov.

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