Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis
Public ClinicalTrials.gov record NCT00430677. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II/III Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Abatacept Versus Placebo on a Background of Mycophenolate Mofetil and Glucocorticosteroids in Subjects With Active Proliferative Glomerulonephritis Due to Systemic Lupus Erythematosus (SLE)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this clinical research study is to learn if addition of abatacept is safe and improves the effectiveness of treatment of patients with active lupus nephritis who are also taking mycophenolate mofetil (MMF) and corticosteroids.
Study identification
- NCT ID
- NCT00430677
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 423 participants
Conditions and interventions
Conditions
Interventions
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2007 (Type not available)
- Primary completion
- Sep 2010 (Actual)
- Completion
- Aug 2011 (Actual)
- Last update posted
- Mar 20, 2015
2007 – 2011
United States locations
- U.S. sites
- 14
- U.S. states
- 11
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University Of Alabama At Birmingham | Birmingham | Alabama | 35294 | — |
| Arizona Arthritis Center | Tucson | Arizona | 85724 | — |
| Wallace Rheumatic Study Center | Los Angeles | California | 90048 | — |
| University Of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Boston University School Of Medicine | Boston | Massachusetts | 02118 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Suny Downstate Medical Center | Brooklyn | New York | 11203 | — |
| Northshore Lij Health System | Lake Success | New York | 11042 | — |
| The Feinstein Institute For Medical Research | Manhasset | New York | 11030 | — |
| Suny Upstate Medical University | Syracuse | New York | 13210 | — |
| University Of North Carolina At Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Ok Medical Research Foundation | Oklahoma City | Oklahoma | 73104 | — |
| Rheumatology Consultants Pllc | Knoxville | Tennessee | 37909 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 70 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00430677, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 20, 2015 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00430677 live on ClinicalTrials.gov.