ClinicalTrials.gov record
S0354, Anti-IL-6 Chimeric Monoclonal Antibody in Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy
ClinicalTrials.gov ID: NCT00433446
Public ClinicalTrials.gov record NCT00433446. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Study of CNTO 328, A Monoclonal Antibody Against Interleukin-6 (IL-6), in Patients With Hormone Refractory Prostate Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Monoclonal antibodies, such as anti-IL-6 chimeric monoclonal antibody, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. PURPOSE: This phase II trial is studying how well anti-IL-6 chimeric monoclonal antibody works in treating patients with metastatic prostate cancer that did not respond to hormone therapy.
Study identification
- NCT ID
- NCT00433446
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 62 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2007 (Type not available)
- Primary completion
- May 2009 (Actual)
- Completion
- Jul 2011 (Actual)
- Last update posted
- Feb 5, 2013
2007 – 2011
United States locations
- U.S. sites
- 123
- U.S. states
- 22
- U.S. cities
- 80
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Regional Medical Center | Anniston | Alabama | 36202 | — |
| Highlands Oncology Group - Springdale | Springdale | Arkansas | 72764 | — |
| Alta Bates Summit Comprehensive Cancer Center | Berkeley | California | 94704 | — |
| Peninsula Medical Center | Burlingame | California | 94010 | — |
| Glendale Memorial Hospital Comprehensive Cancer Center | Glendale | California | 91204 | — |
| Marin Cancer Institute at Marin General Hospital | Greenbrae | California | 94904 | — |
| Sutter Health - Western Division Cancer Research Group | Greenbrae | California | 94904 | — |
| USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | 90089-9181 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| California Pacific Medical Center - California Campus | San Francisco | California | 94118 | — |
| Sutter Solano Medical Center | Vallejo | California | 94589 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| M.D. Anderson Cancer Center at Orlando | Orlando | Florida | 32806 | — |
| Veterans Affairs Medical Center - Hines | Hines | Illinois | 60141 | — |
| Genesis Regional Cancer Center at Genesis Medical Center | Davenport | Iowa | 52803 | — |
| Cancer Center of Kansas, PA - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas, PA - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas, PA - El Dorado | El Dorado | Kansas | 67042 | — |
| Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| Cancer Center of Kansas, PA - Kingman | Kingman | Kansas | 67068 | — |
| Southwest Medical Center | Liberal | Kansas | 67901 | — |
| Cancer Center of Kansas, PA - Newton | Newton | Kansas | 67114 | — |
| Cancer Center of Kansas, PA - Parsons | Parsons | Kansas | 67357 | — |
| Cancer Center of Kansas, PA - Pratt | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas, PA - Salina | Salina | Kansas | 67042 | — |
| Cancer Center of Kansas, PA - Wellington | Wellington | Kansas | 67152 | — |
| Associates in Womens Health, PA - North Review | Wichita | Kansas | 67203 | — |
| Cancer Center of Kansas, PA - Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas, PA - Wichita | Wichita | Kansas | 67214 | — |
| CCOP - Wichita | Wichita | Kansas | 67214 | — |
| Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas, PA - Winfield | Winfield | Kansas | 67156 | — |
| Pennington Cancer Center at Baton Rouge General | Baton Rouge | Louisiana | 70806 | — |
| Mary Bird Perkins Cancer Center - Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Medical Center of Louisiana - New Orleans | New Orleans | Louisiana | 70112 | — |
| Saint Joseph Mercy Cancer Center | Ann Arbor | Michigan | 48106-0995 | — |
| CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | 48106 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0942 | — |
| Battle Creek Health System Cancer Care Center | Battle Creek | Michigan | 49017 | — |
| Mecosta County Medical Center | Big Rapids | Michigan | 49307 | — |
| Oakwood Cancer Center at Oakwood Hospital and Medical Center | Dearborn | Michigan | 48123-2500 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Butterworth Hospital at Spectrum Health | Grand Rapids | Michigan | 49503 | — |
| CCOP - Grand Rapids | Grand Rapids | Michigan | 49503 | — |
| Lacks Cancer Center at Saint Mary's Health Care | Grand Rapids | Michigan | 49503 | — |
| Metro Health Hospital | Grand Rapids | Michigan | 49506 | — |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Grosse Pointe Woods | Michigan | 48236 | — |
| Holland Community Hospital | Holland | Michigan | 49423 | — |
| Foote Memorial Hospital | Jackson | Michigan | 49201 | — |
| Sparrow Regional Cancer Center | Lansing | Michigan | 48912-1811 | — |
| St. Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| Ted B. Wahby Cancer Center at Mount Clemens General Hospital | Mount Clemens | Michigan | 48043 | — |
| Hackley Hospital | Muskegon | Michigan | 49442 | — |
| St. Joseph Mercy Oakland | Pontiac | Michigan | 48341-2985 | — |
| Mercy Regional Cancer Center at Mercy Hospital | Port Huron | Michigan | 48060 | — |
| Seton Cancer Institute at Saint Mary's - Saginaw | Saginaw | Michigan | 48601 | — |
| Munson Medical Center | Traverse City | Michigan | 49684 | — |
| St. John Macomb Hospital | Warren | Michigan | 48093 | — |
| University of Mississippi Cancer Clinic | Jackson | Mississippi | 39216 | — |
| CCOP - Cancer Research for the Ozarks | Springfield | Missouri | 65802 | — |
| St. John's Regional Health Center | Springfield | Missouri | 65804 | — |
| Hulston Cancer Center at Cox Medical Center South | Springfield | Missouri | 65807 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| Hematology-Oncology Centers of the Northern Rockies - Billings | Billings | Montana | 59101 | — |
| Northern Rockies Radiation Oncology Center | Billings | Montana | 59101 | — |
| St. Vincent Healthcare Cancer Care Services | Billings | Montana | 59101 | — |
| Billings Clinic - Downtown | Billings | Montana | 59107-7000 | — |
| Bozeman Deaconess Cancer Center | Bozeman | Montana | 59715 | — |
| St. James Healthcare Cancer Care | Butte | Montana | 59701 | — |
| Big Sky Oncology | Great Falls | Montana | 59405-5309 | — |
| Great Falls Clinic - Main Facility | Great Falls | Montana | 59405 | — |
| Sletten Cancer Institute at Benefis Healthcare | Great Falls | Montana | 59405 | — |
| Not listed | Great Falls | Montana | 59405 | — |
| St. Peter's Hospital | Helena | Montana | 59601 | — |
| Glacier Oncology, PLLC | Kalispell | Montana | 59901 | — |
| Kalispell Medical Oncology at KRMC | Kalispell | Montana | 59901 | — |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | — |
| Community Medical Center | Missoula | Montana | 59801 | — |
| Guardian Oncology and Center for Wellness | Missoula | Montana | 59804 | — |
| Montana Cancer Specialists at Montana Cancer Center | Missoula | Montana | 59807-7877 | — |
| Montana Cancer Center at St. Patrick Hospital and Health Sciences Center | Missoula | Montana | 59807 | — |
| Good Samaritan Cancer Center at Good Samaritan Hospital | Kearney | Nebraska | 68848-1990 | — |
| Tucker Center for Cancer Care at Orange Regional Medical Center | Middletown | New York | 10940-4199 | — |
| Interlakes Oncology/Hematology PC | Rochester | New York | 14623 | — |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Presbyterian Cancer Center at Presbyterian Hospital | Charlotte | North Carolina | 28233-3549 | — |
| Wayne Memorial Hospital, Incorporated | Goldsboro | North Carolina | 27534 | — |
| Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| Rutherford Hospital | Rutherfordton | North Carolina | 28139 | — |
| Legacy Mount Hood Medical Center | Gresham | Oregon | 97030 | — |
| Providence Milwaukie Hospital | Milwaukie | Oregon | 97222 | — |
| Legacy Good Samaritan Hospital & Comprehensive Cancer Center | Portland | Oregon | 97210 | — |
| Providence Cancer Center at Providence Portland Medical Center | Portland | Oregon | 97213-2967 | — |
| Adventist Medical Center | Portland | Oregon | 97216 | — |
| CCOP - Columbia River Oncology Program | Portland | Oregon | 97225 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| Legacy Emanuel Hospital and Health Center and Children's Hospital | Portland | Oregon | 97227 | — |
| Legacy Meridian Park Hospital | Tualatin | Oregon | 97062 | — |
| AnMed Cancer Center | Anderson | South Carolina | 29621 | — |
| CCOP - Upstate Carolina | Spartanburg | South Carolina | 29303 | — |
| Gibbs Regional Cancer Center at Spartanburg Regional Medical Center | Spartanburg | South Carolina | 29303 | — |
| Veterans Affairs Medical Center - San Antonio (Murphy) | San Antonio | Texas | 78209 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229-3900 | — |
| Cancer Therapy and Research Center | San Antonio | Texas | 78229 | — |
| University Hospital - San Antonio | San Antonio | Texas | 78229 | — |
| Danville Regional Medical Center | Danville | Virginia | 24541 | — |
| Ravenel Oncology Center at Memorial Hospital of Martinsville and Henry County | Martinsville | Virginia | 24115 | — |
| St. Joseph Cancer Center | Bellingham | Washington | 98225 | — |
| Olympic Hematology and Oncology | Bremerton | Washington | 98310 | — |
| Columbia Basin Hematology | Kennewick | Washington | 99336 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98104 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Minor and James Medical, PLLC | Seattle | Washington | 98104 | — |
| Group Health Central Hospital | Seattle | Washington | 98112 | — |
| Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle | Washington | 98122-4307 | — |
| Polyclinic First Hill | Seattle | Washington | 98122 | — |
| University Cancer Center at University of Washington Medical Center | Seattle | Washington | 98195-6043 | — |
| Cancer Care Northwest - Spokane South | Spokane | Washington | 99202 | — |
| Southwest Washington Medical Center Cancer Center | Vancouver | Washington | 98668 | — |
| Wenatchee Valley Medical Center | Wenatchee | Washington | 98801-2028 | — |
| Welch Cancer Center at Sheridan Memorial Hospital | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00433446, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 5, 2013 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00433446 live on ClinicalTrials.gov.