ClinicalTrials.gov record
S0635: Erlotinib and Bevacizumab in Stage IIIB and IV Bronchioloalveolar Carcinoma
ClinicalTrials.gov ID: NCT00436332
Public ClinicalTrials.gov record NCT00436332. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Trial of the Combination of OSI-774 (ERLOTINIB; NSC-718781) and Bevacizumab (Rhumab VEGF; NSC-704865) in Stage IIIB and IV Bronchioloalveolar Carcinoma (BAC) and Adenocarcinoma With BAC Features (ADENOBAC)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving erlotinib together with bevacizumab may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving erlotinib together with bevacizumab works in treating patients with stage III or stage IV non-small cell lung cancer.
Study identification
- NCT ID
- NCT00436332
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 84 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2007 (Type not available)
- Primary completion
- Jul 20, 2019 (Actual)
- Completion
- Aug 20, 2019 (Actual)
- Last update posted
- Apr 2, 2020
2007 – 2019
United States locations
- U.S. sites
- 148
- U.S. states
- 15
- U.S. cities
- 112
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kaiser Permanente - Deer Valley | Antioch | California | 94531 | — |
| Alta Bates Summit Comprehensive Cancer Center | Berkeley | California | 94704 | — |
| Peninsula Medical Center | Burlingame | California | 94010 | — |
| Kaiser Permanente - Fremont | Fremont | California | 94538 | — |
| Kaiser Permanente Medical Center - Hayward | Hayward | California | 94545 | — |
| Tibotec Therapeutics - Division of Ortho Biotech Products, LP | Marysville | California | 95901 | — |
| Kaiser Permanente Medical Center - Oakland | Oakland | California | 94611 | — |
| Valley Medical Oncology Consultants - Pleasanton | Pleasanton | California | 94588 | — |
| Kaiser Permanente Medical Center - Redwood City | Redwood City | California | 94063 | — |
| Kaiser Permanente Medical Center - Richmond | Richmond | California | 94801 | — |
| Kaiser Permanente Medical Center - Roseville | Roseville | California | 95661 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| South Sacramento Kaiser-Permanente Medical Center | Sacramento | California | 95823 | — |
| Kaiser Permanente Medical Center - Sacramento | Sacramento | California | 95825 | — |
| Kaiser Permanente Medical Center - San Francisco Geary Campus | San Francisco | California | 94115 | — |
| California Pacific Medical Center - California Campus | San Francisco | California | 94118 | — |
| Kaiser Permanente Medical Center - Santa Teresa | San Jose | California | 95119 | — |
| Kaiser Foundation Hospital - San Rafael | San Rafael | California | 94903 | — |
| Sutter Health - Western Division Cancer Research Group | San Rafael | California | 94903 | — |
| Kaiser Permanente Medical Center - Santa Clara Kiely Campus | Santa Clara | California | 95051 | — |
| Kaiser Permanente Medical Center - Santa Rosa | Santa Rosa | California | 95403 | — |
| Kaiser Permanente Medical Center - South San Francisco | South San Francisco | California | 94080 | — |
| Kaiser Permanente Medical Facility - Stockton | Stockton | California | 95210 | — |
| Tahoe Forest Cancer Center | Truckee | California | 96161 | — |
| Kaiser Permanente Medical Center - Vacaville | Vacaville | California | 95688 | — |
| Kaiser Permanente Medical Center - Vallejo | Vallejo | California | 94589 | — |
| Sutter Solano Medical Center | Vallejo | California | 94589 | — |
| Kaiser Permanente Medical Center - Walnut Creek | Walnut Creek | California | 94596 | — |
| Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center | Hartford | Connecticut | 06105 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Northside Hospital Cancer Center | Atlanta | Georgia | 30342-1611 | — |
| Saint Joseph's Hospital of Atlanta | Atlanta | Georgia | 30342-1701 | — |
| CCOP - Atlanta Regional | Atlanta | Georgia | 30342 | — |
| WellStar Cobb Hospital | Austell | Georgia | 30106 | — |
| John B. Amos Cancer Center | Columbus | Georgia | 31904 | — |
| Charles B. Eberhart Cancer Center at DeKalb Medical Center | Decatur | Georgia | 30033 | — |
| Piedmont Fayette Hospital | Fayetteville | Georgia | 30214 | — |
| Northeast Georgia Medical Center | Gainesville | Georgia | 30501 | — |
| Gwinnett Medical Center | Lawrenceville | Georgia | 30045 | — |
| Kennestone Cancer Center at Wellstar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| Southern Regional Medical Center | Riverdale | Georgia | 30274-2600 | — |
| Harbin Clinic Cancer Center - Medical Oncology | Rome | Georgia | 30165 | — |
| Kaiser Permanente - Moanalua Medical Center and Clinic | Honolulu | Hawaii | 96819 | — |
| Decatur Memorial Hospital Cancer Care Institute | Decatur | Illinois | 62526 | — |
| Cardinal Bernardin Cancer Center at Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Regional Cancer Center at Memorial Medical Center | Springfield | Illinois | 62781-0001 | — |
| Cancer Center of Kansas, PA - Chanute | Chanute | Kansas | 66720 | — |
| Cancer Center of Kansas, PA - Dodge City | Dodge City | Kansas | 67801 | — |
| Cancer Center of Kansas, PA - El Dorado | El Dorado | Kansas | 67042 | — |
| Cancer Center of Kansas - Fort Scott | Fort Scott | Kansas | 66701 | — |
| Cancer Center of Kansas-Independence | Independence | Kansas | 67301 | — |
| Cancer Center of Kansas, PA - Kingman | Kingman | Kansas | 67068 | — |
| Lawrence Memorial Hospital | Lawrence | Kansas | 66044 | — |
| Cancer Center of Kansas, PA - Liberal | Liberal | Kansas | 67901 | — |
| Cancer Center of Kansas, PA - Newton | Newton | Kansas | 67114 | — |
| Cancer Center of Kansas, PA - Parsons | Parsons | Kansas | 67357 | — |
| Cancer Center of Kansas, PA - Pratt | Pratt | Kansas | 67124 | — |
| Cancer Center of Kansas, PA - Salina | Salina | Kansas | 67401 | — |
| Tammy Walker Cancer Center at Salina Regional Health Center | Salina | Kansas | 67401 | — |
| Cotton-O'Neil Cancer Center | Topeka | Kansas | 66606 | — |
| Cancer Center of Kansas, PA - Wellington | Wellington | Kansas | 67152 | — |
| Associates in Womens Health, PA - North Review | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas, PA - Medical Arts Tower | Wichita | Kansas | 67208 | — |
| Cancer Center of Kansas, PA - Wichita | Wichita | Kansas | 67214 | — |
| CCOP - Wichita | Wichita | Kansas | 67214 | — |
| Via Christi Cancer Center at Via Christi Regional Medical Center | Wichita | Kansas | 67214 | — |
| Cancer Center of Kansas, PA - Winfield | Winfield | Kansas | 67156 | — |
| Lucille P. Markey Cancer Center at University of Kentucky | Lexington | Kentucky | 40536-0093 | — |
| Saint Joseph Mercy Cancer Center | Ann Arbor | Michigan | 48106-0995 | — |
| CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | 48106 | — |
| Battle Creek Health System Cancer Care Center | Battle Creek | Michigan | 49017 | — |
| Mecosta County Medical Center | Big Rapids | Michigan | 49307 | — |
| Oakwood Cancer Center at Oakwood Hospital and Medical Center | Dearborn | Michigan | 48123-2500 | — |
| Genesys Hurley Cancer Institute | Flint | Michigan | 48503 | — |
| Hurley Medical Center | Flint | Michigan | 48503 | — |
| Genesys Regional Medical Center | Grand Blanc | Michigan | 48439 | — |
| Butterworth Hospital at Spectrum Health | Grand Rapids | Michigan | 49503 | — |
| CCOP - Grand Rapids | Grand Rapids | Michigan | 49503 | — |
| Lacks Cancer Center at Saint Mary's Health Care | Grand Rapids | Michigan | 49503 | — |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Grosse Pointe Woods | Michigan | 48236 | — |
| Foote Memorial Hospital | Jackson | Michigan | 49201 | — |
| Sparrow Regional Cancer Center | Lansing | Michigan | 48912-1811 | — |
| St. Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| Mercy General Health Partners | Muskegon | Michigan | 49443 | — |
| St. Joseph Mercy Oakland | Pontiac | Michigan | 48341-2985 | — |
| Mercy Regional Cancer Center at Mercy Hospital | Port Huron | Michigan | 48060 | — |
| Seton Cancer Institute at Saint Mary's - Saginaw | Saginaw | Michigan | 48601 | — |
| Munson Medical Center | Traverse City | Michigan | 49684 | — |
| St. John Macomb Hospital | Warren | Michigan | 48093 | — |
| Metro Health Hospital | Wyoming | Michigan | 49519 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| St. Vincent Healthcare Cancer Care Services | Billings | Montana | 59101 | — |
| Hematology-Oncology Centers of the Northern Rockies - Billings | Billings | Montana | 59102 | — |
| Billings Clinic - Downtown | Billings | Montana | 59107-7000 | — |
| Bozeman Deaconess Cancer Center | Bozeman | Montana | 59715 | — |
| St. James Healthcare Cancer Care | Butte | Montana | 59701 | — |
| Big Sky Oncology | Great Falls | Montana | 59405-5309 | — |
| Great Falls Clinic - Main Facility | Great Falls | Montana | 59405 | — |
| Sletten Cancer Institute at Benefis Healthcare | Great Falls | Montana | 59405 | — |
| Northern Montana Hospital | Havre | Montana | 59501 | — |
| St. Peter's Hospital | Helena | Montana | 59601 | — |
| Glacier Oncology, PLLC | Kalispell | Montana | 59901 | — |
| Kalispell Medical Oncology at KRMC | Kalispell | Montana | 59901 | — |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | — |
| Montana Cancer Specialists at Montana Cancer Center | Missoula | Montana | 59807-7877 | — |
| Montana Cancer Center at St. Patrick Hospital and Health Sciences Center | Missoula | Montana | 59807 | — |
| Wayne Memorial Hospital, Incorporated | Goldsboro | North Carolina | 27534 | — |
| Pardee Memorial Hospital | Hendersonville | North Carolina | 28791 | — |
| Mary Rutan Hospital | Bellefontaine | Ohio | 43311 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 45601 | — |
| Riverside Methodist Hospital Cancer Care | Columbus | Ohio | 43214-3998 | — |
| CCOP - Columbus | Columbus | Ohio | 43215 | — |
| Grant Medical Center Cancer Care | Columbus | Ohio | 43215 | — |
| Mount Carmel Health - West Hospital | Columbus | Ohio | 43222 | — |
| Doctors Hospital at Ohio Health | Columbus | Ohio | 43228 | — |
| Grady Memorial Hospital | Delaware | Ohio | 43015 | — |
| Fairfield Medical Center | Lancaster | Ohio | 43130 | — |
| Strecker Cancer Center at Marietta Memorial Hospital | Marietta | Ohio | 45750 | — |
| Knox Community Hospital | Mount Vernon | Ohio | 43050 | — |
| Licking Memorial Cancer Care Program at Licking Memorial Hospital | Newark | Ohio | 43055 | — |
| Community Hospital of Springfield and Clark County | Springfield | Ohio | 45505 | — |
| Mount Carmel St. Ann's Cancer Center | Westerville | Ohio | 43081 | — |
| Genesis - Good Samaritan Hospital | Zanesville | Ohio | 43701 | — |
| Hollings Cancer Center at Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| American Fork Hospital | American Fork | Utah | 84003 | — |
| Sandra L. Maxwell Cancer Center | Cedar City | Utah | 84720 | — |
| Logan Regional Hospital | Logan | Utah | 84321 | — |
| Jon and Karen Huntsman Cancer Center at Intermountain Medical Center | Murray | Utah | 84157 | — |
| Val and Ann Browning Cancer Center at McKay-Dee Hospital Center | Ogden | Utah | 84403 | — |
| Utah Valley Regional Medical Center - Provo | Provo | Utah | 84604 | — |
| Utah Cancer Specialists at UCS Cancer Center | Salt Lake City | Utah | 84106 | — |
| LDS Hospital | Salt Lake City | Utah | 84143 | — |
| Dixie Regional Medical Center - East Campus | St. George | Utah | 84770 | — |
| St. Joseph Cancer Center | Bellingham | Washington | 98225 | — |
| Olympic Hematology and Oncology | Bremerton | Washington | 98310 | — |
| Columbia Basin Hematology | Kennewick | Washington | 99336 | — |
| Skagit Valley Hospital Cancer Care Center | Mount Vernon | Washington | 98274 | — |
| Harrison Poulsbo Hematology and Onocology | Poulsbo | Washington | 98370 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Minor and James Medical, PLLC | Seattle | Washington | 98104 | — |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
| Group Health Central Hospital | Seattle | Washington | 98112 | — |
| Swedish Cancer Institute at Swedish Medical Center - First Hill Campus | Seattle | Washington | 98122-4307 | — |
| University Cancer Center at University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Cancer Care Northwest - Spokane South | Spokane | Washington | 99202 | — |
| Evergreen Hematology and Oncology, PS | Spokane | Washington | 99218 | — |
| Wenatchee Valley Medical Center | Wenatchee | Washington | 98801-2028 | — |
| Welch Cancer Center at Sheridan Memorial Hospital | Sheridan | Wyoming | 82801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00436332, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 2, 2020 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00436332 live on ClinicalTrials.gov.