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Terminated Phase 2 Interventional Results available

Brain Metastases In ErbB2-Positive Breast Cancer

ClinicalTrials.gov ID: NCT00437073

Public ClinicalTrials.gov record NCT00437073. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 9:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Study EGF107671 - a Phase II Study of Lapatinib Plus Topotecan or Lapatinib Plus Capecitabine in the Treatment of Recurrent Brain Metastases From ErbB2-Positive Breast Cancer Following Cranial Radiotherapy

Study identification

NCT ID
NCT00437073
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
22 participants

Conditions and interventions

Interventions

  • capecitabine Drug
  • topotecan Drug
  • lapatinib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2007
Primary completion
Dec 31, 2008
Completion
Jan 31, 2010
Last update posted
Oct 14, 2015

2007 – 2010

United States locations

U.S. sites
13
U.S. states
11
U.S. cities
13
Facility City State ZIP Site status
GSK Investigational Site Washington D.C. District of Columbia 20007
GSK Investigational Site Indianapolis Indiana 46202
GSK Investigational Site Sioux City Iowa 51101-1733
GSK Investigational Site Boston Massachusetts 02115
GSK Investigational Site Minneapolis Minnesota 55455
GSK Investigational Site Rochester Minnesota 55905
GSK Investigational Site Albuquerque New Mexico 87131-0001
GSK Investigational Site Cary North Carolina 27518
GSK Investigational Site Portland Oregon 97239
GSK Investigational Site Philadelphia Pennsylvania 19104
GSK Investigational Site Pittsburgh Pennsylvania 15213
GSK Investigational Site Spartanburg South Carolina 29303
GSK Investigational Site Dallas Texas 75230

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00437073, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 14, 2015 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00437073 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →