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Terminated Phase 3 Interventional Results available

A Study of Subcutaneous Mircera for the Treatment of Anemia in Peritoneal Dialysis Patients.

ClinicalTrials.gov ID: NCT00442416

Public ClinicalTrials.gov record NCT00442416. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 10:28 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Two-arm, Randomized, Open-label, Multicenter Study of Safety and Efficacy of Monthly Injections of RO0503821 Versus Epoetin Alfa in Peritoneal Dialysis Patients Who Self Inject or Receive In-center Injections.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This 2 arm study will compare the efficacy of monthly Mircera and epoetin alfa in peritoneal dialysis patients who self-inject at home or receive in-centre injections. The safety of subcutaneous (sc) Mircera and injection site reactions and patient satisfaction will also be assessed. Eligible patients will be randomized either to receive monthly sc injections of Mircera (and will be switched from sc epoetin alfa) at a starting dose of 120-360 micrograms, or to remain on standard of care sc epoetin alfa. Dose adjustments will be permitted to reach/maintain a hemoglobin level of 10-12g/dL. The anticipated time on study treatment is 3-12 months, and the target sample size is 380 individuals.

Study identification

NCT ID
NCT00442416
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
80 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2007
Primary completion
Dec 31, 2007
Completion
Dec 31, 2007
Last update posted
Aug 16, 2016

2007 – 2008

United States locations

U.S. sites
29
U.S. states
15
U.S. cities
29
Facility City State ZIP Site status
Not listed Birmingham Alabama 35213
Not listed Bakersfield California 93309
Not listed Chula Vista California 91910
Not listed Mountain View California 94041
Not listed San Leandro California 94578
Not listed Simi Valley California 93065
Not listed Whittier California 90602
Not listed Lakewood Colorado 80214
Not listed Stamford Connecticut 06902
Not listed Ocala Florida 34471
Not listed Pembroke Pines Florida 33028
Not listed Augusta Georgia 30901
Not listed Marietta Georgia 30060
Not listed Wichita Kansas 67214
Not listed Detroit Michigan 48236
Not listed Pontiac Michigan 48341
Not listed Flushing New York 11355
Not listed Syracuse New York 13212
Not listed Williamsville New York 14221
Not listed Dayton Ohio 45408
Not listed Toledo Ohio 43606
Not listed Tulsa Oklahoma 74120
Not listed Lewistown Pennsylvania 17044
Not listed Philadelphia Pennsylvania 19106
Not listed Dyersburg Tennessee 38024
Not listed San Antonio Texas 78215
Not listed Tyler Texas 75701
Not listed Alexandria Virginia 22304
Not listed Richmond Virginia 23229

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00442416, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 16, 2016 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00442416 live on ClinicalTrials.gov.

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