Efficacy And Safety Of Pregabalin For Pain Following Total Knee Replacement
Public ClinicalTrials.gov record NCT00442546. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-Blind Randomized, Placebo-Controlled Study Of The Efficacy And Safety Of Pregabalin In The Treatment Of Subjects With Post-Operative Pain Following Total Knee Arthroplasty (TKA)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Pregabalin added to the standard of care with dosing starting preoperatively and continuing for up to 6 weeks post surgery will decrease the intensity of post-operative pain following total knee replacement.
Study identification
- NCT ID
- NCT00442546
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 307 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2007 (Type not available)
- Primary completion
- Dec 2008 (Actual)
- Completion
- Dec 2008 (Actual)
- Last update posted
- Jan 22, 2021
2007 – 2008
United States locations
- U.S. sites
- 27
- U.S. states
- 13
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pfizer Investigational Site | Northport | Alabama | 35476 | — |
| Pfizer Investigational Site | Tuscaloosa | Alabama | 35401 | — |
| Pfizer Investigational Site | Tuscaloosa | Alabama | 35406 | — |
| Pfizer Investigational Site | Phoenix | Arizona | 85023 | — |
| Pfizer Investigational Site | Little Rock | Arkansas | 72205 | — |
| Pfizer Investigational Site | Miami | Florida | 331036 | — |
| Pfizer Investigational Site | Vero Beach | Florida | 32960 | — |
| Pfizer Investigational Site | Chicago | Illinois | 60612 | — |
| Pfizer Investigational Site | Galesburg | Illinois | 61401 | — |
| Pfizer Investigational Site | Lafayette | Louisiana | 70503 | — |
| Pfizer Investigational Site | New Iberia | Louisiana | 70563 | — |
| Pfizer Investigational Site | Baltimore | Maryland | 21218 | — |
| Pfizer Investigational Site | Egg Harbor | New Jersey | 08234 | — |
| Pfizer Investigational Site | Pomona | New Jersey | 08205 | — |
| Pfizer Investigational Site | Voorhees Township | New Jersey | 08043 | — |
| Pfizer Investigational Site | New York | New York | 10021 | — |
| Pfizer Investigational Site | Charlotte | North Carolina | 28207 | — |
| Pfizer Investigational Site | Columbus | Ohio | 43214 | — |
| Pfizer Investigational Site | Columbus | Ohio | 43215 | — |
| Pfizer Investigational Site | Upper Arlington | Ohio | 43220 | — |
| Pfizer Investigational Site | Allentown | Pennsylvania | 18103 | — |
| Pfizer Investigational Site | King of Prussia | Pennsylvania | 19406 | — |
| Pfizer Investigational Site | Philadelphia | Pennsylvania | 19107 | — |
| Pfizer Investigational Site | Pittsburgh | Pennsylvania | 15213-2582 | — |
| Pfizer Investigational Site | Pittsburgh | Pennsylvania | 15232 | — |
| Pfizer Investigational Site | Dallas | Texas | 75390 | — |
| Pfizer Investigational Site | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00442546, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 22, 2021 · Synced Oct 29, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00442546 live on ClinicalTrials.gov.