S0337, Gemcitabine After Surgery in Treating Patients With Newly Diagnosed or Recurrent Bladder Cancer
Public ClinicalTrials.gov record NCT00445601. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Blinded Study of Immediate Post TURBT Instillation of Gemcitabine Versus Saline in Patients With Newly Diagnosed or Occasionally Recurring Grade I/II Superficial Bladder Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving gemcitabine directly into the bladder after surgery may kill more tumor cells. It is not yet known whether giving gemcitabine directly into the bladder is more effective than a placebo in treating bladder cancer. PURPOSE: This randomized phase III trial is studying gemcitabine to see how well it works when given directly into the bladder compared with a placebo after surgery in treating patients with newly diagnosed or recurrent bladder cancer.
Study identification
- NCT ID
- NCT00445601
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 406 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 120 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2007 (Type not available)
- Primary completion
- Jun 2017 (Actual)
- Completion
- Jun 2017 (Actual)
- Last update posted
- Jan 18, 2020
2007 – 2017
United States locations
- U.S. sites
- 70
- U.S. states
- 17
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California Davis Cancer Center | Sacramento | California | 95817 | — |
| University of Colorado Cancer Center at UC Health Sciences Center | Aurora | Colorado | 80045 | — |
| Urology Center of Colorado | Denver | Colorado | 80211 | — |
| Veterans Affairs Medical Center - Denver | Denver | Colorado | 80220 | — |
| St. Joseph Regional Medical Center | Lewiston | Idaho | 83501 | — |
| Cardinal Bernardin Cancer Center at Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| St. Rose Ambulatory and Surgery Center | Great Bend | Kansas | 67530 | — |
| Hays Medical Center | Hays | Kansas | 67601 | — |
| Hutchinson Hospital Corporation | Hutchinson | Kansas | 67502 | — |
| Kansas City Cancer Centers - West | Kansas City | Kansas | 66112 | — |
| Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | Kansas City | Kansas | 66160-7357 | — |
| Kansas City Cancer Centers - Southwest | Overland Park | Kansas | 66210 | — |
| Mount Carmel Regional Cancer Center | Pittsburg | Kansas | 66762 | — |
| Tammy Walker Cancer Center at Salina Regional Health Center | Salina | Kansas | 67401 | — |
| Kansas City Cancer Center - Shawnee Mission | Shawnee Mission | Kansas | 66204 | — |
| St. Francis Comprehensive Cancer Center | Topeka | Kansas | 66606 | — |
| Feist-Weiller Cancer Center at Louisiana State University Health Sciences | Shreveport | Louisiana | 71130-3932 | — |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109-0942 | — |
| Josephine Ford Cancer Center at Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| William Beaumont Hospital - Royal Oak Campus | Royal Oak | Michigan | 48073 | — |
| Truman Medical Center - Hospital Hill | Kansas City | Missouri | 64108 | — |
| Veterans Affairs Medical Center - Kansas City | Kansas City | Missouri | 64128 | — |
| Kansas City Cancer Centers - South | Kansas City | Missouri | 64131 | — |
| Kansas City Cancer Centers - North | Kansas City | Missouri | 64154 | — |
| Kansas City Cancer Centers - East | Lee's Summit | Missouri | 64064 | — |
| CCOP - Montana Cancer Consortium | Billings | Montana | 59101 | — |
| St. Vincent Healthcare Cancer Care Services | Billings | Montana | 59101 | — |
| Hematology-Oncology Centers of the Northern Rockies - Billings | Billings | Montana | 59102 | — |
| Billings Clinic - Downtown | Billings | Montana | 59107-7000 | — |
| Bozeman Deaconess Cancer Center | Bozeman | Montana | 59715 | — |
| St. James Healthcare Cancer Care | Butte | Montana | 59701 | — |
| Great Falls Clinic - Main Facility | Great Falls | Montana | 59405 | — |
| Sletten Cancer Institute at Benefis Healthcare | Great Falls | Montana | 59405 | — |
| Northern Montana Hospital | Havre | Montana | 59501 | — |
| St. Peter's Hospital | Helena | Montana | 59601 | — |
| Glacier Oncology, PLLC | Kalispell | Montana | 59901 | — |
| Kalispell Medical Oncology at KRMC | Kalispell | Montana | 59901 | — |
| Kalispell Regional Medical Center | Kalispell | Montana | 59901 | — |
| Montana Cancer Specialists at Montana Cancer Center | Missoula | Montana | 59807-7877 | — |
| Montana Cancer Center at St. Patrick Hospital and Health Sciences Center | Missoula | Montana | 59807 | — |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Blumenthal Cancer Center at Carolinas Medical Center | Charlotte | North Carolina | 28232-2861 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Oklahoma University Cancer Institute | Oklahoma City | Oklahoma | 73104 | — |
| Bay Area Hospital | Coos Bay | Oregon | 97420 | — |
| Knight Cancer Institute at Oregon Health and Science University | Portland | Oregon | 97239-3098 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234-6200 | — |
| M. D. Anderson Cancer Center at University of Texas | Houston | Texas | 77030-4009 | — |
| Baylor University Medical Center - Houston | Houston | Texas | 77030 | — |
| Methodist Hospital | Houston | Texas | 77030 | — |
| Veterans Affairs Medical Center - Houston | Houston | Texas | 77030 | — |
| Wilford Hall Medical Center | Lackland Air Force Base | Texas | 78236 | — |
| Veterans Affairs Medical Center - San Antonio (Murphy) | San Antonio | Texas | 78209 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229-3900 | — |
| Cancer Therapy and Research Center | San Antonio | Texas | 78229 | — |
| University Hospital - San Antonio | San Antonio | Texas | 78229 | — |
| Overlake Cancer Center at Overlake Hospital Medical Center | Bellevue | Washington | 98004 | — |
| Providence Centralia Hospital | Centralia | Washington | 98531-9027 | — |
| Providence Regional Cancer Partnership | Everett | Washington | 98201 | — |
| St. Francis Hospital | Federal Way | Washington | 98003 | — |
| Providence St. Peter Hospital Regional Cancer Center | Olympia | Washington | 98506-5166 | — |
| Good Samaritan Cancer Center | Puyallup | Washington | 98372 | — |
| Franciscan Cancer Center at St. Joseph Medical Center | Tacoma | Washington | 98405-3004 | — |
| Allenmore Hospital | Tacoma | Washington | 98405 | — |
| CCOP - Northwest | Tacoma | Washington | 98405 | — |
| MultiCare Regional Cancer Center at Tacoma General Hospital | Tacoma | Washington | 98405 | — |
| Madigan Army Medical Center - Tacoma | Tacoma | Washington | 98431 | — |
| St. Clare Hospital | Tacoma | Washington | 98499 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00445601, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 18, 2020 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00445601 live on ClinicalTrials.gov.