ClinicalTrials.gov record
Strategies in Maintenance for Patients Receiving Long-term Therapy (S.I.M.P.L.E.) With MMX (Multi-Matrix System) Mesalamine for Ulcerative Colitis (UC)
ClinicalTrials.gov ID: NCT00446849
Public ClinicalTrials.gov record NCT00446849. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase IV, Multi-center, Open-label Study to Assess Clinical Recurrence Related to Compliance With Treatment With MMX Mesalamine 2.4g/Day Given Once Daily for the Maintenance of Quiescent Ulcerative Colitis (UC)
Study identification
- NCT ID
- NCT00446849
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Shire
- Industry
- Enrollment
- 290 participants
Conditions and interventions
Conditions
Interventions
- MMX Mesalamine Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2007
- Primary completion
- Aug 16, 2009
- Completion
- Aug 16, 2009
- Last update posted
- Jun 13, 2021
2007 – 2009
United States locations
- U.S. sites
- 62
- U.S. states
- 29
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Birmingham Gastroenterology Assoc. | Birmingham | Alabama | 35209 | — |
| Clopton Clinic | Jonesboro | Arkansas | 72401 | — |
| VA Medical Center - Long Beach | Long Beach | California | 90822 | — |
| Sharp Rees-Stealy Medical Group | San Diego | California | 92101 | — |
| Clinical Applications Laboratories, Inc. | San Diego | California | 92103 | — |
| South Denver Gastroenterology, P.C. | Englewood | Colorado | 80113 | — |
| The Center for GI Medicine of Fairfield & Westchester, P.C. | Greenwich | Connecticut | 06830 | — |
| Medical Research Center of Connecticut, LLC | Hamden | Connecticut | 06518 | — |
| Connecticut Gastroenterology Associates | New Haven | Connecticut | 06510 | — |
| Walter Reed Army Medical Center | Washington D.C. | District of Columbia | 20307 | — |
| Advanced Digestive Care, PA | Clearwater | Florida | 33756 | — |
| Southern Clinical Research Consultants | Hollywood | Florida | 33021 | — |
| Borland-Groover Clinic | Jacksonville | Florida | 32256 | — |
| United Medical Research | New Smyrna Beach | Florida | 32168 | — |
| Advanced Gastroenterology Associates | Palm Harbor | Florida | 34684 | — |
| Soapstone Ctr. for Clin. Rsrch | Decatur | Georgia | 30034 | — |
| Gastroenterology Assoc./Cen.GA | Macon | Georgia | 31201 | — |
| NW GA Gastroenterology | Marietta | Georgia | 30060 | — |
| Midwest Clinical Research Associates | Moline | Illinois | 61265 | — |
| Accelovance | Peoria | Illinois | 61602 | — |
| Rockford Gastroenterology Associates | Rockford | Illinois | 61107 | — |
| Indiana University Hospital | Indianapolis | Indiana | 46202 | — |
| Gastrointestinal Clinic of Quad Cities | Davenport | Iowa | 52807 | — |
| University of Iowa Hospital and Clinics | Iowa City | Iowa | 52242 | — |
| GI Associates | Overland Park | Kansas | 66212 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71103 | — |
| Digestive Disorders Associates Research Division | Annapolis | Maryland | 21401 | — |
| Maryland Clinical Trials | Annapolis | Maryland | 21401 | — |
| Maryland Digestive Disease Research, LLC | Laurel | Maryland | 20707 | — |
| Center for Digestive Health | Troy | Michigan | 48098 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| Center for Digestive and Liver Diseases | Mexico | Missouri | 65265 | — |
| Clinical Research Group of Montana, PLLC | Bozeman | Montana | 59718 | — |
| Marlboro Gastroenterology | Manalapan | New Jersey | 07726 | — |
| Western Suffolk Gastroenterology Associates, LLP | Bay Shore | New York | 11706 | — |
| Long Island Clinical Research Associates, LLP | Long Island City | New York | 11021 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Digestive Medicine of Long Island | New Hyde Park | New York | 11042 | — |
| Mount Sinai and Metropolitan Hospital | New York | New York | 10128 | — |
| Upstate Gastroentrology Associates | Troy | New York | 12180 | — |
| Peters Medical Research | High Point | North Carolina | 27262 | — |
| East Carolina Gastroenterology | Jacksonville | North Carolina | 28546 | — |
| Gastroenterology Associates | Beachwood | Ohio | 44122 | — |
| Consultants for Clinical Research, Inc. | Cincinnati | Ohio | 45219 | — |
| Digestive Health Network | Cincinnati | Ohio | 45220 | — |
| Gastro Consultants of Greater Cincinnati | Cincinnati | Ohio | 45242 | — |
| Gild Consultants, P.C. | Dayton | Ohio | 45415 | — |
| Central Sooner Research | Norman | Oklahoma | 73069 | — |
| Guthrie Clinic | Sayre | Pennsylvania | 18840 | — |
| ClinSearch | Chattanooga | Tennessee | 37404 | — |
| Gastroenterology of Midsouth | Germantown | Tennessee | 38138 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Houston Endoscopy & Research Center | Houston | Texas | 77024 | — |
| Gastroenterology Clinic of San Antonio | San Antonio | Texas | 78229 | — |
| Gastroenterology Associates of Tidewater | Chesapeake | Virginia | 23320 | — |
| New River Valley Research | Christiansburg | Virginia | 24073 | — |
| Inland Empire Gastroenterology, P.S. | Spokane | Washington | 99204 | — |
| Spokane Digestive Disease Center, P.S. | Spokane | Washington | 99204 | — |
| Wisconsin Center for Advanced Research | Milwaukee | Wisconsin | 53215 | — |
| Aurora Sinai Medical Center | Milwaukee | Wisconsin | 53233 | — |
| Aurora Health Center- Waukesha | Waukesha | Wisconsin | 53186 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00446849, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 13, 2021 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00446849 live on ClinicalTrials.gov.