Open-Label Extension Study of Rufinamide Given as Adjunctive Therapy in Patients With Refractory Partial Seizures
Public ClinicalTrials.gov record NCT00448539. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label Extension Study of Rufinamide Given as Adjunctive Therapy in Patients With Refractory Partial Seizures
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This was an open-label extension study in adolescent and adult (between 12 and 80 years old) participants who had completed their participation in Study E2080-A001-301. The main objective of this study was to evaluate the safety and efficacy of long-term administration of rufinamide for the control of epileptic seizures in participants who had refractory partial seizures despite treatment with a maximum of three approved antiepileptic drugs (AEDs).
Study identification
- NCT ID
- NCT00448539
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 286 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 15, 2007 (Actual)
- Primary completion
- May 14, 2010 (Actual)
- Completion
- May 14, 2010 (Actual)
- Last update posted
- Nov 22, 2019
2007 – 2010
United States locations
- U.S. sites
- 27
- U.S. states
- 17
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama Medical Center | Mobile | Alabama | 36693 | — |
| Clinical Trials, Inc. | Little Rock | Arkansas | 72205 | — |
| Bradenton Research Center | Bradenton | Florida | 34205 | — |
| University of Florida, The Neuroscience Institute at Shands | Jacksonville | Florida | 32209 | — |
| Pediatric Neurologists of Palm Beach | Loxahatchee Groves | Florida | 33470 | — |
| Pediatric Neurosciences, PA | Orlando | Florida | 32835 | — |
| Bay Medical Center | Panama City | Florida | 32405 | — |
| Child Neurology Associates, PC | Atlanta | Georgia | 30342 | — |
| Southern Illinois University Neurology and Pharmacology | Springfield | Illinois | 62794-9643 | — |
| McFarland Clinic PC | Ames | Iowa | 50010-3014 | — |
| John Hopkins Hospital, Dept. of Neurology | Baltimore | Maryland | 21287 | — |
| Hattiesburg Clinic | Hattiesburg | Mississippi | 39401 | — |
| Comprehensive Epilepsy Care Center for Children and Adults | Chesterfield | Missouri | 63017 | — |
| Dartmouth Medical School Neuroscience Center | Lebanon | New Hampshire | 03756-0001 | — |
| Five Towns Neuroscience Research | Cedarhurst | New York | 11516 | — |
| New York University Medical Centre, Comprehensive Epilepsy Center | New York | New York | 10016 | — |
| Weill Cornell Medical Center, Comprehensive Epilepsy Center | New York | New York | 10021 | — |
| Asheville Neurology Specialists | Asheville | North Carolina | 28806 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Medical University of Ohio at Toledo - Dept. of Neurology | Toledo | Ohio | — | — |
| Hospital of The University of Pennsylvania | Philadelphia | Pennsylvania | 19104-4204 | — |
| University of Pennsylvania Medical Center-Department of Neurology | Philadelphia | Pennsylvania | 19104-4283 | — |
| University of Tennessee Health Sciences Center, Dept. of Neurology | Memphis | Tennessee | 38105 | — |
| Access Clinical Trials, Inc | Nashville | Tennessee | 37203 | — |
| Neurological Clinic of Texas, P.A. | Dallas | Texas | 75230 | — |
| Texas Tech University Health Sciences Center, Dept. of Neuropsychiatry | El Paso | Texas | 79905 | — |
| Fletcher Allen Healthcare | Burlington | Vermont | 05401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00448539, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 22, 2019 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00448539 live on ClinicalTrials.gov.