Efficacy and Safety Study of Oral BG00012 With Active Reference in Relapsing-Remitting Multiple Sclerosis
Public ClinicalTrials.gov record NCT00451451. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Multicenter, Placebo-Controlled and Active Reference (Glatiramer Acetate) Comparison Study to Evaluate the Efficacy and Safety of BG00012 in Subjects With Relapsing-Remitting Multiple Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To determine if treatment with BG00012 can decrease the number of MS relapses during a certain time period. Other goals of the study are to determine if, over time, BG00012 treatment can decrease the number of certain types of brain lesions commonly seen in MS patients and slow down the time it takes for MS to get worse. Other objectives of the study are to determine the safety and tolerability of BG00012, as well as the effect it may have on tests and evaluations used to assess MS. Additionally, glatiramer acetate is being used to compare its benefits and risks with placebo and BG00012.
Study identification
- NCT ID
- NCT00451451
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,417 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 55 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2007 (Type not available)
- Primary completion
- Aug 2011 (Actual)
- Completion
- Aug 2011 (Actual)
- Last update posted
- Jan 26, 2015
2007 – 2011
United States locations
- U.S. sites
- 72
- U.S. states
- 29
- U.S. cities
- 72
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | — | — |
| Research Site | Cullman | Alabama | — | — |
| Research Site | Huntsville | Alabama | — | — |
| Research Site | Phoenix | Arizona | — | — |
| Research Site | La Jolla | California | — | — |
| Research Site | Loma Linda | California | — | — |
| Research Site | Pasadena | California | — | — |
| Research Site | Sacramento | California | — | — |
| Research Site | Walnut Creek | California | — | — |
| Research Site | Boulder | Colorado | — | — |
| Research Site | Colorado Springs | Colorado | — | — |
| Research Site | Fort Collins | Colorado | — | — |
| Research Site | Maitland | Florida | — | — |
| Research Site | Miami | Florida | — | — |
| Research Site | Naples | Florida | — | — |
| Research Site | Pompano Beach | Florida | — | — |
| Research Site | Sarasota | Florida | — | — |
| Research Site | St. Petersburg | Florida | — | — |
| Research Site | Tallahassee | Florida | — | — |
| Research Site | Tampa | Florida | — | — |
| Research Site | Augusta | Georgia | — | — |
| Research Site | Columbus | Georgia | — | — |
| Research Site | Meridan | Idaho | — | — |
| Research Site | Indianapolis | Indiana | — | — |
| Research Site | Kansas City | Kansas | — | — |
| Research Site | Louisville | Kentucky | — | — |
| Research Site | Shreveport | Louisiana | — | — |
| Research Site | Baltimore | Maryland | — | — |
| Research Site | Boston | Massachusetts | — | — |
| Research Site | Clinton Township | Michigan | — | — |
| Research Site | Grand Rapids | Michigan | — | — |
| Research Site | Dover | New Hampshire | — | — |
| Research Site | Lebanon | New Hampshire | — | — |
| Research Site | Freehold | New Jersey | — | — |
| Research Site | Teaneck | New Jersey | — | — |
| Research Site | Amherst | New York | — | — |
| Research Site | Buffalo | New York | — | — |
| Research Site | Cedarhurst | New York | — | — |
| Research Site | Mineola | New York | — | — |
| Research Site | Patchogue | New York | — | — |
| Research Site | Plainview | New York | — | — |
| Research Site | Staten Island | New York | — | — |
| Research Site | Stony Brook | New York | — | — |
| Research Site | Charlotte | North Carolina | — | — |
| Research Site | Winston-Salem | North Carolina | — | — |
| Research Site | Bellevue | Ohio | — | — |
| Research Site | Cleveland | Ohio | — | — |
| Research Site | Columbus | Ohio | — | — |
| Research Site | Edmond | Oklahoma | — | — |
| Research Site | Eugene | Oregon | — | — |
| Research Site | Medford | Oregon | — | — |
| Research Site | Portland | Oregon | — | — |
| Research Site | Philadelphia | Pennsylvania | — | — |
| Research Site | Pittsburgh | Pennsylvania | — | — |
| Research Site | Souderton | Pennsylvania | — | — |
| Research Site | Cordova | Tennessee | — | — |
| Research Site | Franklin | Tennessee | — | — |
| Research Site | Knoxville | Tennessee | — | — |
| Research Site | Memphis | Tennessee | — | — |
| Research Site | Nashville | Tennessee | — | — |
| Research Site | Dallas | Texas | — | — |
| Research Site | Galveston | Texas | — | — |
| Research Site | Houston | Texas | — | — |
| Research Site | Round Rock | Texas | — | — |
| Research Site | San Antonio | Texas | — | — |
| Research Site | Salt Lake City | Utah | — | — |
| Research Site | Burlington | Vermont | — | — |
| Research Site | Richmond | Virginia | — | — |
| Research Site | Seattle | Washington | — | — |
| Research Site | Tacoma | Washington | — | — |
| Research Site | Madison | Wisconsin | — | — |
| Research Site | Milwaukee | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 123 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00451451, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 26, 2015 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00451451 live on ClinicalTrials.gov.