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Terminated Phase 2 Interventional Results available

Mitoxantrone, Prednisone Plus Sorafenib in Taxane-Refractory Metastatic Hormone Refractory Prostate Cancer (HRPC)

ClinicalTrials.gov ID: NCT00452387

Public ClinicalTrials.gov record NCT00452387. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 28, 2026, 12:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this research study is to determine if the combination of mitoxantrone, prednisone and sorafenib will improve the time to progression of advanced stage metastatic hormone-refractory prostate cancer.

Study identification

NCT ID
NCT00452387
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Enrollment
22 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 30, 2007
Primary completion
Jun 30, 2008
Completion
Dec 31, 2008
Last update posted
Sep 15, 2011

2007 – 2009

United States locations

U.S. sites
10
U.S. states
7
U.S. cities
10
Facility City State ZIP Site status
Wilshire Oncology Medical Group, Inc. La Verne California 91750 —
Peachtree Hematology Oncology Consultants Atlanta Georgia 30309 —
Central Georgia Cancer Care Macon Georgia 31201 —
Northwest Georgia Oncology Centers Marietta Georgia 30060 —
Hematology Oncology Centers of the Northern Rockies, PC Billings Montana 59101 —
Mid-Ohio Oncology/Hematology, Inc. Columbus Ohio 43213 —
Lancaster Cancer Center Lancaster Pennsylvania 17605 —
Pennsylvania Oncology Hematmology Associates Philadelphia Pennsylvania 19106 —
The West Clinic Memphis Tennessee 38120 —
Cancer Specialists of Tidewater Chesapeake Virginia 23320 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00452387, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 15, 2011 · Synced Sep 28, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00452387 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →