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Completed Phase 1 Interventional Results available

Investigational Agent AG-013736 In Combinations With Standard Of Care Treatments For Patient's With Advanced Solid Tumor

ClinicalTrials.gov ID: NCT00454649

Public ClinicalTrials.gov record NCT00454649. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 17, 2026, 8:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Dose-Finding Study Of The Anti-Angiogenesis Agent, AG-013736, In Combinations Of Paclitaxel/Carboplatin, Weekly Paclitaxel, Docetaxel, Capecitabine, Gemcitabine/Cisplatin and Pemetrexed/Cisplatin In Patients With Advanced Solid Tumors

Study identification

NCT ID
NCT00454649
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Pfizer
Industry
Enrollment
102 participants

Conditions and interventions

Conditions

Interventions

  • Axitinib + Capecitabine (Cohort 6) Drug
  • Axitinib + Capecitabine (Cohort 7) Drug
  • Axitinib + Docetaxel (Cohort 5) Drug
  • Axitinib + Docetaxel + Carboplatin (Cohort 4a) Drug
  • Axitinib + Gemcitabine + Cisplatin (Cohort 8) Drug
  • Axitinib + Paclitaxel (Cohort 4) Drug
  • Axitinib + Paclitaxel + Carboplatin (Cohort 1) Drug
  • Axitinib + Paclitaxel + Carboplatin (Cohort 2) Drug
  • Axitinib + Paclitaxel + Carboplatin (Cohort 3) Drug
  • Axitinib + Pemetrexed + Cisplatin (Cohort 9) Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2005
Primary completion
Jul 31, 2009
Completion
Mar 31, 2011
Last update posted
Apr 3, 2012

2005 – 2011

United States locations

U.S. sites
10
U.S. states
6
U.S. cities
8
Facility City State ZIP Site status
Pfizer Investigational Site Augusta Georgia 30909
Pfizer Investigational Site Augusta Georgia 30912
Pfizer Investigational Site Harvey Illinois 60426-4265
Pfizer Investigational Site Harvey Illinois 60426
Pfizer Investigational Site Tinley Park Illinois 60477
Pfizer Investigational Site Hobart Indiana 46342
Pfizer Investigational Site Munster Indiana 46321
Pfizer Investigational Site Philadelphia Pennsylvania 19111
Pfizer Investigational Site Houston Texas 77030-4009
Pfizer Investigational Site Kennewick Washington 99336

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00454649, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 3, 2012 · Synced May 17, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00454649 live on ClinicalTrials.gov.

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