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Completed Phase 2 Interventional Results available

PARTNER: Panitumumab Added to Regimen for Treatment of Head aNd Neck Cancer Evaluation of Response

ClinicalTrials.gov ID: NCT00454779

Public ClinicalTrials.gov record NCT00454779. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 9:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Open-Label, Controlled, Phase II Trial of Combination Chemotherapy With or Without Panitumumab as First-line Treatment of Subjects With Metastatic or Recurrent Head and Neck Cancer, and Cross-over Second-line Panitumumab Monotherapy of Subjects Who Fail the Combination Chemotherapy…

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized, open-label, 2-arm, controlled, phase 2, multi-center, estimation clinical trial of docetaxel and cisplatin combination chemotherapy with and without panitumumab in the first-line treatment of subjects with metastatic or recurrent head and neck cancer, as well as a cross-over second-line panitumumab monotherapy of subjects who fail the chemotherapy only arm. This study will be conducted in the United States. Approximately 150 subjects with histologically or cytologically confirmed metastatic and/or recurrent SCCHN.

Study identification

NCT ID
NCT00454779
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Amgen
Industry
Enrollment
113 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2006
Primary completion
Jun 10, 2012
Completion
Dec 31, 2013
Last update posted
Oct 16, 2018

2007 – 2014

United States locations

U.S. sites
82
U.S. states
31
U.S. cities
70
Facility City State ZIP Site status
Research Site Tucson Arizona 85715
Research Site Jonesboro Arkansas 72401
Research Site Duarte California 91010
Research Site La Jolla California 92037
Research Site La Verne California 91750
Research Site Los Angeles California 90095
Research Site Santa Cruz California 95065
Research Site Aurora Colorado 80045
Research Site Denver Colorado 80210
Research Site Norwich Connecticut 06360
Research Site Newark Delaware 19713
Research Site Washington D.C. District of Columbia 20007
Research Site Washington D.C. District of Columbia 20010
Research Site Washington D.C. District of Columbia 20037
Research Site Washington D.C. District of Columbia 20422
Research Site Lakeland Florida 33805
Research Site Miami Florida 33176
Research Site New Port Richey Florida 34655
Research Site Orlando Florida 32806
Research Site Athens Georgia 30607
Research Site Griffin Georgia 30224
Research Site Marietta Georgia 30060
Research Site Centralia Illinois 62801
Research Site Elk Grove Village Illinois 60007
Research Site Evanston Illinois 60201
Research Site Park Ridge Illinois 60068
Research Site Zion Illinois 60099
Research Site Wichita Kansas 67214
Research Site Ashland Kentucky 41101
Research Site Lexington Kentucky 40536
Research Site Louisville Kentucky 40202-1703
Research Site Louisville Kentucky 40202
Research Site Paducah Kentucky 42003
Research Site Baltimore Maryland 21204
Research Site Baltimore Maryland 21237
Research Site Frederick Maryland 21701
Research Site Boston Massachusetts 02114
Research Site Ann Arbor Michigan 48106-0995
Research Site Lansing Michigan 48910
Research Site Pascagoula Mississippi 39581
Research Site Columbia Missouri 65201
Research Site Jefferson City Missouri 65109
Research Site St Louis Missouri 63110-1093
Research Site St Louis Missouri 63110
Research Site Billings Montana 59102
Research Site Omaha Nebraska 68114
Research Site Henderson Nevada 59074
Research Site Hackensack New Jersey 07601
Research Site Binghamton New York 13905
Research Site Mineola New York 11501
Research Site New York New York 10003
Research Site New York New York 10032
Research Site Nyack New York 10960
Research Site Rochester New York 14623
Research Site Syracuse New York 13210
Research Site The Bronx New York 10457
Research Site The Bronx New York 10467
Research Site Canton Ohio 44718
Research Site Cincinnati Ohio 45236
Research Site Dayton Ohio 45420
Research Site Toledo Ohio 43614
Research Site Oklahoma City Oklahoma 73104
Research Site Langhorne Pennsylvania 19047
Research Site Philadelphia Pennsylvania 19107
Research Site Scranton Pennsylvania 18510
Research Site Charleston South Carolina 29406
Research Site Charleston South Carolina 29425
Research Site Greenville South Carolina 29615
Research Site Memphis Tennessee 38120
Research Site Arlington Texas 76012
Research Site Corpus Christi Texas 78405
Research Site Corpus Christi Texas 78412
Research Site Dallas Texas 75201
Research Site Dallas Texas 75230
Research Site Dallas Texas 75234
Research Site Galveston Texas 77555-0158
Research Site San Antonio Texas 78229
Research Site Abingdon Virginia 24211
Research Site Chesapeake Virginia 23320
Research Site Morgantown West Virginia 26506
Research Site Madison Wisconsin 53792
Research Site Marshfield Wisconsin 54449

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00454779, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 16, 2018 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00454779 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →