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Completed Phase 2 Interventional Results available

PARTNER: Panitumumab Added to Regimen for Treatment of Head aNd Neck Cancer Evaluation of Response

ClinicalTrials.gov ID: NCT00454779

Public ClinicalTrials.gov record NCT00454779. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 4:50 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Open-Label, Controlled, Phase II Trial of Combination Chemotherapy With or Without Panitumumab as First-line Treatment of Subjects With Metastatic or Recurrent Head and Neck Cancer, and Cross-over Second-line Panitumumab Monotherapy of Subjects Who Fail the Combination Chemotherapy…

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized, open-label, 2-arm, controlled, phase 2, multi-center, estimation clinical trial of docetaxel and cisplatin combination chemotherapy with and without panitumumab in the first-line treatment of subjects with metastatic or recurrent head and neck cancer, as well as a cross-over second-line panitumumab monotherapy of subjects who fail the chemotherapy only arm. This study will be conducted in the United States. Approximately 150 subjects with histologically or cytologically confirmed metastatic and/or recurrent SCCHN.

Study identification

NCT ID
NCT00454779
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Amgen
Industry
Enrollment
113 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 1, 2007 (Actual)
Primary completion
Jun 11, 2012 (Actual)
Completion
Jan 1, 2014 (Actual)
Last update posted
Oct 17, 2018

2007 – 2014

United States locations

U.S. sites
82
U.S. states
31
U.S. cities
70
Facility City State ZIP Site status
Research Site Tucson Arizona 85715 —
Research Site Jonesboro Arkansas 72401 —
Research Site Duarte California 91010 —
Research Site La Jolla California 92037 —
Research Site La Verne California 91750 —
Research Site Los Angeles California 90095 —
Research Site Santa Cruz California 95065 —
Research Site Aurora Colorado 80045 —
Research Site Denver Colorado 80210 —
Research Site Norwich Connecticut 06360 —
Research Site Newark Delaware 19713 —
Research Site Washington D.C. District of Columbia 20007 —
Research Site Washington D.C. District of Columbia 20010 —
Research Site Washington D.C. District of Columbia 20037 —
Research Site Washington D.C. District of Columbia 20422 —
Research Site Lakeland Florida 33805 —
Research Site Miami Florida 33176 —
Research Site New Port Richey Florida 34655 —
Research Site Orlando Florida 32806 —
Research Site Athens Georgia 30607 —
Research Site Griffin Georgia 30224 —
Research Site Marietta Georgia 30060 —
Research Site Centralia Illinois 62801 —
Research Site Elk Grove Village Illinois 60007 —
Research Site Evanston Illinois 60201 —
Research Site Park Ridge Illinois 60068 —
Research Site Zion Illinois 60099 —
Research Site Wichita Kansas 67214 —
Research Site Ashland Kentucky 41101 —
Research Site Lexington Kentucky 40536 —
Research Site Louisville Kentucky 40202-1703 —
Research Site Louisville Kentucky 40202 —
Research Site Paducah Kentucky 42003 —
Research Site Baltimore Maryland 21204 —
Research Site Baltimore Maryland 21237 —
Research Site Frederick Maryland 21701 —
Research Site Boston Massachusetts 02114 —
Research Site Ann Arbor Michigan 48106-0995 —
Research Site Lansing Michigan 48910 —
Research Site Pascagoula Mississippi 39581 —
Research Site Columbia Missouri 65201 —
Research Site Jefferson City Missouri 65109 —
Research Site St Louis Missouri 63110-1093 —
Research Site St Louis Missouri 63110 —
Research Site Billings Montana 59102 —
Research Site Omaha Nebraska 68114 —
Research Site Henderson Nevada 59074 —
Research Site Hackensack New Jersey 07601 —
Research Site Binghamton New York 13905 —
Research Site Mineola New York 11501 —
Research Site New York New York 10003 —
Research Site New York New York 10032 —
Research Site Nyack New York 10960 —
Research Site Rochester New York 14623 —
Research Site Syracuse New York 13210 —
Research Site The Bronx New York 10457 —
Research Site The Bronx New York 10467 —
Research Site Canton Ohio 44718 —
Research Site Cincinnati Ohio 45236 —
Research Site Dayton Ohio 45420 —
Research Site Toledo Ohio 43614 —
Research Site Oklahoma City Oklahoma 73104 —
Research Site Langhorne Pennsylvania 19047 —
Research Site Philadelphia Pennsylvania 19107 —
Research Site Scranton Pennsylvania 18510 —
Research Site Charleston South Carolina 29406 —
Research Site Charleston South Carolina 29425 —
Research Site Greenville South Carolina 29615 —
Research Site Memphis Tennessee 38120 —
Research Site Arlington Texas 76012 —
Research Site Corpus Christi Texas 78405 —
Research Site Corpus Christi Texas 78412 —
Research Site Dallas Texas 75201 —
Research Site Dallas Texas 75230 —
Research Site Dallas Texas 75234 —
Research Site Galveston Texas 77555-0158 —
Research Site San Antonio Texas 78229 —
Research Site Abingdon Virginia 24211 —
Research Site Chesapeake Virginia 23320 —
Research Site Morgantown West Virginia 26506 —
Research Site Madison Wisconsin 53792 —
Research Site Marshfield Wisconsin 54449 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00454779, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 17, 2018 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT00454779 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →