Study of Apixaban for the Prevention of Thrombosis-related Events in Patients With Acute Medical Illness
Public ClinicalTrials.gov record NCT00457002. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-Blind, Parallel-group, Multi-center Study of the Safety and Efficacy of Apixaban for Prophylaxis of Venous Thromboembolism in Acutely Ill Medical Subjects During and Following Hospitalization.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to learn if apixaban can prevent blood clots in the leg (deep vein thrombosis \[DVT\]) and lung (pulmonary embolism \[PE\]) that sometimes occur within patients hospitalized for acute medical illness, and to learn how apixaban compares to enoxaparin (Lovenox®) for preventing these clots. The safety of apixaban will also be studied.
Study identification
- NCT ID
- NCT00457002
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 6,758 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2007 (Type not available)
- Primary completion
- May 2011 (Actual)
- Completion
- May 2011 (Actual)
- Last update posted
- Dec 8, 2015
2007 – 2011
United States locations
- U.S. sites
- 48
- U.S. states
- 27
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University Of Alabama At Birmingham Hospital | Birmingham | Alabama | 35294 | — |
| Heart Center Research, Llc | Huntsville | Alabama | 35801 | — |
| Arizona Pulmonary Specialists, Ltd. | Phoenix | Arizona | 85013 | — |
| Az Pulmonary Specialists Ltd | Scottsdale | Arizona | 85258 | — |
| Fort Smith Lung Center | Fort Smith | Arkansas | 72901 | — |
| Scripps Clinic/Scripps Health And Green Hospital | La Jolla | California | 92037 | — |
| Va Long Beach Healthcare System | Long Beach | California | 90822 | — |
| Univ. Of Southern Calif. /Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Dr. Felt Medical Office | Oakland | California | 94609 | — |
| Stanford University | Stanford | California | 94305 | — |
| Yale University School Of Medicine | New Haven | Connecticut | 06510 | — |
| Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| George Washington University | Washington D.C. | District of Columbia | 20037 | — |
| Florida Hospital Celebration Health | Celebration | Florida | 34747 | — |
| Research Alliance, Inc. | Clearwater | Florida | 33756 | — |
| Jacksonville Center For Clinical Research | Jacksonville | Florida | 32216 | — |
| Pensacola Lung Group | Pensacola | Florida | 32504 | — |
| Indian River Med. Ctr. | Vero Beach | Florida | 32960 | — |
| Atlanta Institute For Medical Research, Inc | Atlanta | Georgia | 30030 | — |
| Pulmonary & Critical Care Of Atlanta | Atlanta | Georgia | 30342 | — |
| Idaho Falls Infectious Diseases, Pllc | Idaho Falls | Idaho | 83404 | — |
| West Suburban Hospital | Oak Park | Illinois | 60302 | — |
| Infectious Disease Of Indiana Psc | Carmel | Indiana | 46032 | — |
| Cotton-O-Neil Clinical Research Center | Topeka | Kansas | 66604 | — |
| Louisiana State University Health Sciences Center-Shreveport | Shreveport | Louisiana | 71103 | — |
| Johns Hopkins University School Of Medicine | Baltimore | Maryland | 21205 | — |
| Franklin Square Hospital | Baltimore | Maryland | 21237 | — |
| Henry Ford Hospital, Transplant Institute | Detriot | Michigan | 48202 | — |
| University Of Missouri-Columbia | Columbia | Missouri | 65212 | — |
| Mercury Street Medical Group, Pllc | Butte | Montana | 59701 | — |
| Creighton University Medical Center | Omaha | Nebraska | 68131 | — |
| Morristown Memorial Hospital | Mornstown | New Jersey | 07962 | — |
| North Shore University Hospital | Manhasset | New York | 11030 | — |
| Staten Island University Hospital | Staten Island | New York | 10305 | — |
| Mission Hospital, Inc | Asheville | North Carolina | 28801 | — |
| South Oklahoma Heart Research | Oklahoma City | Oklahoma | 73135 | — |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| The Milton S Hershey Medical Center Of Penn. State Univ. | Hershey | Pennsylvania | 17033 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Palmetto Nephrology Pa | Orangeburg | South Carolina | 29118 | — |
| S. Carolina Pharmaceutical Research | Spartanburg | South Carolina | 29303 | — |
| Texas Health Presbyterian Dallas | Dallas | Texas | 75231 | — |
| Michael E. De Bakey Veteran Affairs Medical Center | Houston | Texas | 77030 | — |
| Sonterra Clinical Research | San Antonio | Texas | 78205 | — |
| Sonterra Clinical Research | San Antonio | Texas | 78258 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| University Of Utah Medical Center | Salt Lake City | Utah | 84132 | — |
| Mcguire Va Medical Center | Richmond | Virginia | 23249 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 248 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00457002, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 8, 2015 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00457002 live on ClinicalTrials.gov.