Functional Neuroanatomy of Emotion Perception, Recognition, Learning, and Memory
Public ClinicalTrials.gov record NCT00458432. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study uses magnetic resonance imaging (MRI) to explore the areas of the brain involved in different types of mental processes, in particular, the brain regions involved in perception, recognition, learning, and memory. MRI uses a magnetic field and radio waves to produce images of body tissues and organs. In this study it is also used to measure blood flow in different regions of the brain while the subject is presented auditory or visual stimuli. The subject lies on a table that can slide in and out of the scanner (a narrow cylinder), wearing earplugs to muffle loud noises that occur during the scanning process. Subjects are in the scanner no more than 2 hours. Healthy, right-handed normal volunteers between 20 and 40 years of age who have at least a high school education may be eligible for this study. While undergoing MRI, participants are presented visual stimuli (pictures or geometric shapes on a projection screen) or auditory stimuli (tones played through a set of headphones). Unpleasant stimuli such as loud noise, electric shocks, heat, or tactile stimuli are administered occasionally. The intensity of these stimuli is similar to those experienced in practice sessions before the scanning. Participants receive between 30 and 60 visual or auditory stimuli during the scanning session, and each stimulus lasts about 1 second. In some studies participants are asked to move a joystick that controls a rating bar presented on a projection screen to indicate when they expect to receive these stimuli and how sure they are that they will occur. Heart rate, respiration rate, and sweat gland activity are monitored during the MRI sessions, using electrodes placed on the fingers to measure heart rate and sweat gland activity and a sensor strapped around the chest to measure respiration. Subjects are in the scanner no more than 2 hours. Following the experiment, subjects may be asked questions about their experiences during the study.
Study identification
- NCT ID
- NCT00458432
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 180 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 20 Years to 40 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 4, 2007
- Primary completion
- Aug 30, 2009
- Completion
- Aug 30, 2009
- Last update posted
- Jul 1, 2017
2007 – 2009
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| National Institutes of Health Clinical Center, 9000 Rockville Pike | Bethesda | Maryland | 20892 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00458432, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 1, 2017 · Synced Sep 12, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00458432 live on ClinicalTrials.gov.