Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-611)
Public ClinicalTrials.gov record NCT00461591. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Placebo-Controlled, Double-Blind, Phase 3 Trial of Single Dose Intravesical Apaziquone (EOquin®) as a Surgical Adjuvant Instilled in the Early Postoperative Period in Patients Undergoing Transurethral Resection for Noninvasive Bladder Cancer (Protocol SPI-611)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to evaluate the 2-Year Recurrence Rate of bladder cancer in randomized patients with tumor histology Ta, G1-G2 who received TransUrethral Resection of Bladder Tumor (TURBT) plus apaziquone versus those who received TURBT plus placebo.
Study identification
- NCT ID
- NCT00461591
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 802 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2007 (Actual)
- Primary completion
- Jan 2012 (Actual)
- Completion
- Jan 2012 (Actual)
- Last update posted
- Mar 30, 2021
2007 – 2012
United States locations
- U.S. sites
- 74
- U.S. states
- 27
- U.S. cities
- 71
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Clinical Research Center, LLC | Anchorage | Alaska | 99508 | — |
| BCG Oncology | Phoenix | Arizona | 85032 | — |
| Sun Health Research Institute | Sun City | Arizona | 85032 | — |
| Urology Associates Medical Group | Burbank | California | 91505 | — |
| Urology Associates of Central CA | Fresno | California | 93720 | — |
| South Orange County Medical Research Center | Laguna Woods | California | 92653 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Cancer Research Dept/St. Joseph Hospital | Orange | California | 92868 | — |
| San Bernardino Urologic Association | San Bernardino | California | 92404 | — |
| VA Medical Center | San Francisco | California | 94121 | — |
| The Urology Center of Colorado | Denver | Colorado | 80211 | — |
| Connecticut Clinical Research Center | Middlebury | Connecticut | 06762 | — |
| Urologic Surgeons of Washington | Washington D.C. | District of Columbia | 20006 | — |
| Lakeland Regional Cancer Center | Lakeland | Florida | 33805 | — |
| Urology Consultants | Longwood | Florida | 32750 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Advanced Research Institute | New Port Richey | Florida | 34652 | — |
| Advanced Research Institute | New Port Richey | Florida | 34655 | — |
| Florida Foundation for Healthcare Research | Ocala | Florida | 34474 | — |
| Florida Urology Specialists | Sarasota | Florida | 34237 | — |
| Southeastern Research Group, Inc. | Tallahassee | Florida | 32308 | — |
| Gainesville Urology, PC | Gainesville | Georgia | 30501 | — |
| Urological Professional Association | Macon | Georgia | 31217 | — |
| North Idaho Urology | Coeur d'Alene | Idaho | 83814 | — |
| Idaho Urologic Institute, P.A. | Meridian | Idaho | 83642 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Urology Associates, SC | Mattoon | Illinois | 61938 | — |
| Speciality Care Research | Peoria | Illinois | 61614 | — |
| Northeast Indiana Research, LLC | Fort Wayne | Indiana | 46825 | — |
| Metropolitan Urology | Jeffersonville | Indiana | 47130 | — |
| Kansas City Urology Care, P.A. | Overland Park | Kansas | 66211 | — |
| Regional Urology, LLC | Shreveport | Louisiana | 71106 | — |
| Anne Arundel Urology | Annapolis | Maryland | 21401 | — |
| Myron Murdock, MD, LLC | Greenbelt | Maryland | 20770 | — |
| MMPC Urology | Grand Rapids | Michigan | 49546 | — |
| Lakeside Urology, PC | Saint Joseph | Michigan | 49085 | — |
| Michigan Institute of Urology, PC | Troy | Michigan | 48084 | — |
| Five Valleys Urology | Missoula | Montana | 59802 | — |
| Coastal Urological Associates, PA | Brick | New Jersey | 08724 | — |
| AdvanceMed Research | Lawrenceville | New Jersey | 08648 | — |
| Delaware Valley Urology, LLC-Marlton | Marlton | New Jersey | 08053 | — |
| Deleware Valley Urology, LLC-Washington Township | Sewell | New Jersey | 08080 | — |
| Delaware Valley Urology, LLC - Voorhees | Voorhees Township | New Jersey | 08043 | — |
| Delaware Valley Urology, LLC-Westampton | Woodlane | New Jersey | 08060 | — |
| Urology Group of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Capital Region Urological Surgeons | Albany | New York | 12208 | — |
| The Urological Institute of NE NY | Albany | New York | 12208 | — |
| Adult and Pediatric Urology | Carmel | New York | 10512 | — |
| Accumed Research Associates | Garden City | New York | 11530 | — |
| Urological Surgeons of Long Island, P.C. | Garden City | New York | 11530 | — |
| Hudson Valley Urology, PC | Kingston | New York | 12401 | — |
| University Urology Associates | New York | New York | 10016 | — |
| CNY Urology, PC | Oneida | New York | 13421 | — |
| Hudson Valley Urology | Poughkeepsie | New York | 12601 | — |
| Urology Associates of Rochester, LLC | Rochester | New York | 14618 | — |
| Center for Urologic Research of WNY, LLC | Williamsville | New York | 14221 | — |
| TriState Urologic Services PSC, Inc. | Cincinnati | Ohio | 45212 | — |
| Columbus Urology Research, LLC | Columbus | Ohio | 43220 | — |
| Oregon Urology Institute | Springfield | Oregon | 97477 | — |
| Urologic Consultants of South Eastern Pennsylvania | Bala-Cynwyd | Pennsylvania | 19026 | — |
| Urological Associates of Lancaster | Lancaster | Pennsylvania | 17604 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111-2497 | — |
| Triangle Urology Group | Pittsburgh | Pennsylvania | 15212 | — |
| Susquehenna Urology | Williamsport | Pennsylvania | 17701 | — |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | — |
| The Conrad Pearson Clinic | Germantown | Tennessee | 38138 | — |
| Corpus Christi Urology Group LLC | Corpus Christi | Texas | 78404 | — |
| Urology Clinics of North Texas | Dallas | Texas | 75231 | — |
| Urology San Antonio Research | San Antonio | Texas | 78229 | — |
| Mary Washington Hospital and Urology Associates of Fredericksburg | Fredericksburg | Virginia | 22401 | — |
| Urology of Virginia, PC | Norfolk | Virginia | 23502 | — |
| Urology of Virginia, PC | Virginia Beach | Virginia | 23454 | — |
| Integrity Medical Research, LLC | Mountlake Terrace | Washington | 98043 | — |
| Seattle Urological Associates | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00461591, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 30, 2021 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00461591 live on ClinicalTrials.gov.