Open-Label C1 Esterase Inhibitor (C1INH-nf) for the Prevention of Acute Hereditary Angioedema (HAE) Attacks
Public ClinicalTrials.gov record NCT00462709. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
LEVP2006-4 CHANGE 3 Trial (C1-Inhibitor in Hereditary Angioedema Nanofiltration Generation Evaluating Efficacy): Open-Label Use of C1INH-nf (Human) for the Prophylactic Treatment to Prevent HAE Attacks and as Treatment in Acute HAE Attacks
Study identification
- NCT ID
- NCT00462709
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Shire
- Industry
- Enrollment
- 146 participants
Conditions and interventions
Conditions
Interventions
- C1 esterase inhibitor [human] (C1INH-nf) Biological
Biological
Eligibility (public fields only)
- Age range
- 1 Year and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 26, 2006
- Primary completion
- Mar 30, 2009
- Completion
- Mar 30, 2009
- Last update posted
- Jun 7, 2021
2006 – 2009
United States locations
- U.S. sites
- 48
- U.S. states
- 29
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Consultants, Inc | Hoover | Alabama | 35216 | — |
| Allergy and Immunology Associates | Scottsdale | Arizona | 85251 | — |
| Allergy and Asthma Clinic of Northwest Arkansas | Bentonville | Arkansas | 72712 | — |
| UCLA-David Geffen School of Medicine | Los Angeles | California | 90095 | — |
| University of California, San Diego | San Diego | California | 92093 | — |
| Allergy and Asthma Associates of Santa Clara | San Jose | California | 95117 | — |
| Allergy and Asthma Clinical Research, Inc | Walnut Creek | California | 94598 | — |
| Allergy and Asthma Center | Fort Lauderdale | Florida | 33334 | — |
| Allergy and Asthma Center of East Orlando | Orlando | Florida | 32826 | — |
| Cleveland Clinic | Weston | Florida | 33331 | — |
| Family Allergy and Asthma Center | Atlanta | Georgia | 30342 | — |
| Atlanta Allergy and Asthma Clinic | Suwanee | Georgia | 30024 | — |
| University Consultants in Allergy & Immunology | Chicago | Illinois | 60612 | — |
| Welborn Clinic | Evansville | Indiana | 47713 | — |
| Private Practice | Liberal | Kansas | 67901 | — |
| Olathe Medical Center | Olathe | Kansas | 66061 | — |
| Graves-Gilbert Clinic | Bowling Green | Kentucky | 42101 | — |
| Family Asthma and Allergy Research Center | Louisville | Kentucky | 40215 | — |
| Asthma Allergy and Sinus Center | Waldorf | Maryland | 20602 | — |
| Institute for Asthma and Allergy | Wheaton | Maryland | 20902 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Grand Traverse Allergy | Traverse City | Michigan | 49684 | — |
| MeritCare Clinical Research | Bemidji | Minnesota | 56601 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| St. Louis University School of Medicine | St Louis | Missouri | 63110 | — |
| Nevada Access to Research and Education Society | Las Vegas | Nevada | 89102 | — |
| UMDNJ Asthma and Allergy Research Center | Newark | New Jersey | 07103 | — |
| Private Practice | Hastings-on-Hudson | New York | 10706 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| Allergy Partners of East Carolina | Greenville | North Carolina | 27858 | — |
| Legacy Pharma Research | Bismarck | North Dakota | 58501 | — |
| MeritCare Clinical Research | Fargo | North Dakota | 58122 | — |
| Nationwide Childrens Hospital Clinical Research | Columbus | Ohio | 43205 | — |
| Allergy Clinic of Tulsa | Tulsa | Oklahoma | 74133 | — |
| Oregon Medical Group | Eugene | Oregon | 97401 | — |
| Allergy Asthma and Dermatology Research Center | Lake Oswego | Oregon | 97035 | — |
| Penn State University | Hershey | Pennsylvania | 17033 | — |
| AARA Research Center | Dallas | Texas | 75231 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-1083 | — |
| University of Texas - Pediatric Pulmonary/Allergy and Immunology | Houston | Texas | 77030 | — |
| Allergy and Asthma Research Center | San Antonio | Texas | 78229 | — |
| Tyler County Hospital | Woodville | Texas | 75979 | — |
| Virginia Adult and Pediatric Allergy and Asthma | Richmond | Virginia | 23229 | — |
| Marycliff Allergy Specialists | Spokane | Washington | 99204 | — |
| Puget Sound Allergy, Asthma and Immunology | Tacoma | Washington | 98405 | — |
| St. Joseph's Hospital/Cornerstone Healthcare | Parkersburg | West Virginia | 26102 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00462709, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 7, 2021 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT00462709 live on ClinicalTrials.gov.