An Open-Label Study to Compare the Lipid Effects of Niacin ER and Simvastatin (NS) to Atorvastatin in Subjects With Hyperlipidemia or Mixed Dyslipidemia (SUPREME)
Public ClinicalTrials.gov record NCT00465088. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
SUPREME: A 12-Week, Open-Label, Multicenter Study to Compare the Lipid Effects of Niacin ER and Simvastatin (NS) to Atorvastatin in Subjects With Hyperlipidemia or Mixed Dyslipidemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To demonstrate that niacin ER and simvastatin (NS) tablets, when compared to atorvastatin (Lipitor®; Pfizer, Inc.), has superior high-density lipoprotein cholesterol (HDL-C) elevating effects at Week 12 in subjects with type II hyperlipidemia or mixed dyslipidemia who are currently off lipid-modifying therapy. This was a prospective, randomized, open-label, blinded endpoint (PROBE) study.
Study identification
- NCT ID
- NCT00465088
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 199 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2007 (Type not available)
- Primary completion
- Feb 2008 (Actual)
- Completion
- Not listed
- Last update posted
- Jun 13, 2011
Started 2007
United States locations
- U.S. sites
- 46
- U.S. states
- 18
- U.S. cities
- 46
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Anaheim | California | 92801 | — |
| Not listed | Huntington Park | California | 90255 | — |
| Not listed | Long Beach | California | 90822 | — |
| Not listed | Sacramento | California | 95825 | — |
| Not listed | Walnut Creek | California | 94598 | — |
| Not listed | Brooksville | Florida | 34613 | — |
| Not listed | Daytona Beach | Florida | 32117 | — |
| Not listed | Gainesville | Florida | 32605 | — |
| Not listed | Largo | Florida | 33770 | — |
| Not listed | Merritt Island | Florida | 32953 | — |
| Not listed | Miami | Florida | 33126 | — |
| Not listed | Pembroke Pines | Florida | 33026 | — |
| Not listed | Calhoun | Georgia | 30701 | — |
| Not listed | Decatur | Georgia | 30034 | — |
| Not listed | Dunwoody | Georgia | 30338 | — |
| Not listed | Boise | Idaho | 83704 | — |
| Not listed | Chicago | Illinois | 60607 | — |
| Not listed | Arkansas City | Kansas | 67005 | — |
| Not listed | Newton | Kansas | 67114 | — |
| Not listed | Shawnee Mission | Kansas | 66216 | — |
| Not listed | Topeka | Kansas | 55508 | — |
| Not listed | Wichita | Kansas | 67203 | — |
| Not listed | Auburn | Maine | 04210 | — |
| Not listed | Baltimore | Maryland | 21204 | — |
| Not listed | Missoula | Montana | 59808 | — |
| Not listed | Charlotte | North Carolina | 28204 | — |
| Not listed | High Point | North Carolina | 27262 | — |
| Not listed | Canfield | Ohio | 44406 | — |
| Not listed | Cincinnati | Ohio | 45242 | — |
| Not listed | Dayton | Ohio | 45458 | — |
| Not listed | Protland | Oregon | 97239 | — |
| Not listed | Chicora | Pennsylvania | 16025 | — |
| Not listed | Duncansville | Pennsylvania | 16635 | — |
| Not listed | Harleysville | Pennsylvania | 19438 | — |
| Not listed | Pittsburgh | Pennsylvania | 15206 | — |
| Not listed | Austin | Texas | 78752 | — |
| Not listed | Carrollton | Texas | 75006 | — |
| Not listed | Dallas | Texas | 75251 | — |
| Not listed | Houston | Texas | 77074 | — |
| Not listed | San Antonio | Texas | 78224 | — |
| Not listed | Magna | Utah | 84044 | — |
| Not listed | Salt Lake City | Utah | 84107 | — |
| Not listed | Richmond | Virginia | 23249 | — |
| Not listed | Gig Harbor | Washington | 98335 | — |
| Not listed | Menomonee Falls | Wisconsin | 53051 | — |
| Not listed | Milwaukee | Wisconsin | 53209 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00465088, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 13, 2011 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00465088 live on ClinicalTrials.gov.