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Completed Phase 4 Interventional Results available

An Open-label Study of Hydromorphone Oral Solution in Subjects Aged 28 Days to 16 Years for Postoperative Pain

ClinicalTrials.gov ID: NCT00465647

Public ClinicalTrials.gov record NCT00465647. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 1:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multi-center, Open-label, Dose Titration Study Pharmacokinetics/Pharmacodynamics, Safety, and Efficacy of Hydromorphone Oral Solution in Subjects From 28 Days to 16 Years of Age, Who Require Opioid Analgesics for Postoperative Pain

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of this study is to characterize the pharmacokinetics and pharmacodynamics of hydromorphone oral solution in pediatric subjects aged 28 days to 16 years inclusive. The secondary objectives are to characterize the safety and efficacy of hydromorphone oral solution in pediatric subjects aged 28 days to 16 years inclusive.

Study identification

NCT ID
NCT00465647
Recruitment status
Completed
Study type
Interventional
Phase
Phase 4
Lead sponsor
Purdue Pharma LP
Industry
Enrollment
116 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
28 Days to 16 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2007
Primary completion
Apr 30, 2009
Completion
Mar 31, 2010
Last update posted
Nov 17, 2015

2007 – 2010

United States locations

U.S. sites
14
U.S. states
10
U.S. cities
13
Facility City State ZIP Site status
Arkansas Children's Hospital Little Rock Arkansas 72202
Children's Hospital of Orange County - Pediatric Subspecialty Orange California 92868
Stanford University Medical Center Stanford California 94305
The Children's Hospital Aurora Colorado 80218
Yale-New Haven Children's Hospital New Haven Connecticut 06510
Jackson Memorial Hospital Miami Florida 33136
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
Saint Louis University - Department of Neurology and Psychiatry St Louis Missouri 63104
The University of North Carolina - CH Chapel Hill North Carolina 27599-7221
Duke University Medical Center Durham North Carolina 27710
Children's Hospital Medical Center of Akron Akron Ohio 44308
Children's Medical Center Dallas Texas 75235
Texas Children's Hospital / Baylor College of Medicine Houston Texas 77030
The University of Texas, Health Sciences Center at Houston Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT00465647, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 17, 2015 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT00465647 live on ClinicalTrials.gov.

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